Sonlicromanol Mitigates Sepsis-induced Heart Injury via Mitochondrial and Pyroptosis Modulation [0.03%]
索利克罗曼诺尔通过线粒体和吡咯稀释调节缓解脓毒症诱导的心脏损伤
Xinxin Qi,Liang Zhao,Yan Zou
Xinxin Qi
Sepsis-induced myocardial dysfunction (SIMD) is a severe consequence of systemic infection, primarily driven by mitochondrial dysfunction, inflammation, and pyroptosis. Sonlicromanol, a mitochondrial redox-modulating therapeutic agent, has ...
The Impact of Lepidium meyenii (MACA) Supplementation on Basketball-related Performance and Antifatigue Ability: A Double-blind Crossover Study [0.03%]
马卡（Lepidium meyenii）补充对篮球相关表现和抗疲劳能力的影响：一项双盲交叉研究
Po-Sheng Wu,Shih-Hao Wu,Ren-Shiang Jiang et al.
Po-Sheng Wu et al.
Animal studies suggest that Lepidium meyenii (MACA) may reduce exercise-induced fatigue by improving blood lactate clearance. We hypothesized that MACA supplementation would therefore enhance performance in well-trained male basketball play...
Niujiaodihuang Detoxify Decoction Inhibits D-GalN/LPS-induced Hepatocyte Ferroptosis by Maintaining Mitochondrial Homeostasis Via OMA1-OPA1 Pathway [0.03%]
牛胶解毒方通过OMA1-OPA1通路维持线粒体稳态抑制D-GalN/LPS致小鼠肝细胞铁死亡
Yanping Lu,Henghui Sun,Qinyan Zhu et al.
Yanping Lu et al.
Niujiaodihuang Detoxify Decoction (NDD) has been shown to attenuate liver injury during acute liver failure by inhibiting ferroptosis, whereas the specific mechanism regulating ferroptosis remains to be elucidated. The LO2 liver cell injury...
Dry Cupping Attenuates Inflammation Markers and Rated Perceived Exertion in Table Tennis Players after Intensive Training [0.03%]
干拔罐可缓解 intensive training 后乒乓球运动员的炎症标志物和主观疲劳感
Yu-An Yeh,Chi-Cheng Lu,Yi-Ying Chen et al.
Yu-An Yeh et al.
High-intensity training induces inflammation, fatigue, and muscle damage in athletes. Cupping is popular for managing muscle stiffness and fatigue. This study investigated dry cupping's effects on training intensity perception, blood cell p...
SIRT3-mediated Mitochondrial Regulation Underlies Sonlicromanol's Protection against Cerebral Ischemia-reperfusion Injury in Rats [0.03%]
sonlicromanol通过SIRT3介导的线粒体调节保护 rats脑缺血再灌注损伤
Hanfu Zhang,Ugwah-Oguejiofor Chinenye Jane,Junhua Jin
Hanfu Zhang
Cerebral ischemia-reperfusion (IR) injury is a significant contributor to stroke-related morbidity, driven by mitochondrial dysfunction, oxidative stress, and inflammation. This study investigates the neuroprotective effects of sonlicromano...
Muscle Oxygenation during Prolonged Concentric and Eccentric Exercises in Well-trained Males [0.03%]
优秀男性运动员在长时间的离心和向心收缩运动中的肌肉氧合反应
Takashi Yamashita,Taisei Fujino,Yuta Kosuge et al.
Takashi Yamashita et al.
Understanding how training status influences muscle oxygen dynamics during resistance exercise is crucial for optimizing exercise prescriptions and performance adaptations. However, limited information is available regarding muscle oxygenat...
Combination Effect of Caffeine Intake and Thermotherapy on the Blood Levels of Human Irisin and Fibroblast Growth Factor 21 in Healthy Males [0.03%]
咖啡因摄入与热疗对人体健康男性血鸢尾素和成纤维细胞生长因子21水平联合作用的影响
Hye-Jin Lee,Tae-Hwan Park,Bah-Da Yun et al.
Hye-Jin Lee et al.
Caffeine is a widely consumed psychoactive substance known to influence physiological processes such as heat generation and autonomic nervous system activity. Fibroblast growth factor 21 (FGF-21) and irisin are the biomarkers associated wit...
CircERBB3 Targets miR-194-5p/PRMT3 to Promote Hepatocellular Carcinoma Progression [0.03%]
环状RNA CircERBB3通过靶向miR-194-5p/PRMT3促进肝癌进展
Shihao Jiang,Zhihao Bai,Jiaxin Li et al.
Shihao Jiang et al.
The role of circular RNAs in the progression of hepatocellular carcinoma (HCC) is still unclear. This study explored the oncogenic properties of circERBB3 in HCC and the underlying molecular mechanisms. After transfection, cell behaviors in...
Itaconate Attenuates Homocysteine-induced Nod-like Receptor Family Protein 3 Inflammasome-mediated Pyroptosis in Hippocampal Neurons: Involvement of Inhibiting Succinate Dehydrogenase Complex Subunit A Level [0.03%]
衣康酸通过抑制琥珀酸脱氢酶复合物亚基A水平减轻高同型半胱氨酸血症诱导的海马神经元NLRP3炎性小体介导的焦亡
Min Huang,Pan-Pan Zhang,Yi-Yun Tang et al.
Min Huang et al.
Elevated homocysteine (Hcy) levels are associated with various neurodegenerative diseases. Elucidating the pathogenesis of Hcy-associated neurotoxicity and exploring novel approaches for preventing and treating Hcy-induced neurotoxicity are...
Impact of Hyperglycemia on Streptococcus pneumoniae Virulence: Insights into Capsular Dynamics and Clinical Implications [0.03%]
高血糖对肺炎链球菌毒力的影响：荚膜动力学和临床意义的见解
Pin Wang
Pin Wang
Hyperglycemia, a diabetic condition, profoundly affects the pathogenicity of Streptococcus pneumoniae ( S . pneumoniae ), a leading etiologic pathogen of pneumonia. This review addresses a systematic understanding of how hyperglycemia affec...