Pectolinarigenin Induces Mitochondrion-dependent Apoptosis, Causes G2/M Arrest, and Inhibits Migration and Invasion in Rheumatoid Arthritis-Fibroblast-like Synoviocytes [0.03%]
pectorlinarigenin诱导滑膜成纤维细胞线粒体依赖性凋亡、G2 / M停滞并抑制类风湿关节炎的迁移和侵袭
Bing Zhang,Nan Wu,Ying-Hua Luo et al.
Bing Zhang et al.
Natural Defense against Atherosclerosis: The Therapeutic Potential of Torenia concolor Lindley var. Formosana Yamazaki Extract in Inhibiting the Formation of Macrophage-derived Foam Cells [0.03%]
天然抗动脉粥样硬化方法——台湾假紫花地丁提取物抑制巨噬细胞源性泡沫细胞形成的治疗潜力
Chia-Hui Chen,Li-Ching Cheng,Bei-Chia Guo et al.
Chia-Hui Chen et al.
C-C Chemokine Receptor 5 Deficiency Impairs Cardiac and Metabolic Homeostasis, Driving Heart Failure with Preserved Ejection Fraction-like Pathophysiology [0.03%]
C-C趋化因子受体5缺乏损害心脏和代谢稳态，引发射血分数保留的心力衰竭样病理生理学现象
Jiung-Pang Huang,Kuan-Hsing Chen,Chieh-Yu Chang et al.
Jiung-Pang Huang et al.
C-C chemokine receptor 5 (CCR5) regulates immune responses, inflammation, and tissue remodeling, but its baseline role in cardiac and metabolic homeostasis remains unclear. Using CCR5 knockout (KO) mice, we examined the effects of CCR5 defi...
Infectious Carcinogens Derived from Intestinal Microflora: Mechanisms of Microbial Transitions from Eubionts to Pathobionts [0.03%]
源自肠道菌群的传染性致癌物：微生物从正常共生菌向病原菌转变的机制
Yu-Chen Pai,Chung-Yen Huang,Li-Yu Lin et al.
Yu-Chen Pai et al.
A diverse community of microorganisms inhabits the gastrointestinal tract in a physiological state. While a symbiotic relationship exists between commensal bacteria and the healthy host, an imbalanced microbial population (dysbiosis) is ass...
Research Progress on the Effects of Lactylation Modification and m6A Methylation on Programmed Death in Cardiovascular Disease [0.03%]
乳酰化修饰及m６A甲基化调控心血管疾病程序性细胞死亡的研究进展
Chao Yu,Wei Wang,Wen-Sheng Xu et al.
Chao Yu et al.
Programmed cell death (PCD) plays a central regulatory role in the development and progression of cardiovascular diseases (CVD), and its dysregulated activation or inhibition is closely associated with pathological conditions such as myocar...
Gaussian Filter-Based Image Denoising Detects Hidden Sweat Glands and Enhances Reliability of Active Sweat Gland Density Measurements [0.03%]
基于高斯滤波的图像去噪能够检测隐藏汗腺并增强活性汗腺密度测量的可靠性
Seunghyun Lee,Tae-Hwan Park,Jong-In Park et al.
Seunghyun Lee et al.
The quantitative sudomotor axon reflex test (QSART, Iontophoresis of 10% ACh with 2 mA for 5 min) is widely used in perspiration studies. However, it faces challenges such as suboptimal image quality and misidentification of hidden sweat gl...
MiR-193b-3p Regulates Gasdermin-D/NLRP3 by Targeting the Signaling Axis Inhibition of Pyroptosis Attenuates Myocardial Ischemia-Reperfusion Injury [0.03%]
微小核糖核酸-193b通过靶向调控Gasdermin-D/炎性小体信号轴抑制心肌缺血再灌注损伤中的细胞焦亡现象
Chao Yu,Qiu-Ping Zhu,Wei Xie et al.
Chao Yu et al.
The complex pathogenesis of myocardial ischemia-reperfusion (I/R) injury is a major factor influencing clinical prognosis. It has been confirmed that microRNAs are involved in myocardial I/R injury, and that pyroptosis is closely associated...
Sonlicromanol Mitigates Sepsis-induced Heart Injury via Mitochondrial and Pyroptosis Modulation [0.03%]
索利克罗曼诺尔通过线粒体和吡咯稀释调节缓解脓毒症诱导的心脏损伤
Xinxin Qi,Liang Zhao,Yan Zou
Xinxin Qi
Sepsis-induced myocardial dysfunction (SIMD) is a severe consequence of systemic infection, primarily driven by mitochondrial dysfunction, inflammation, and pyroptosis. Sonlicromanol, a mitochondrial redox-modulating therapeutic agent, has ...
The Impact of Lepidium meyenii (MACA) Supplementation on Basketball-related Performance and Antifatigue Ability: A Double-blind Crossover Study [0.03%]
马卡（Lepidium meyenii）补充对篮球相关表现和抗疲劳能力的影响：一项双盲交叉研究
Po-Sheng Wu,Shih-Hao Wu,Ren-Shiang Jiang et al.
Po-Sheng Wu et al.
Animal studies suggest that Lepidium meyenii (MACA) may reduce exercise-induced fatigue by improving blood lactate clearance. We hypothesized that MACA supplementation would therefore enhance performance in well-trained male basketball play...
Niujiaodihuang Detoxify Decoction Inhibits D-GalN/LPS-induced Hepatocyte Ferroptosis by Maintaining Mitochondrial Homeostasis Via OMA1-OPA1 Pathway [0.03%]
牛胶解毒方通过OMA1-OPA1通路维持线粒体稳态抑制D-GalN/LPS致小鼠肝细胞铁死亡
Yanping Lu,Henghui Sun,Qinyan Zhu et al.
Yanping Lu et al.
Niujiaodihuang Detoxify Decoction (NDD) has been shown to attenuate liver injury during acute liver failure by inhibiting ferroptosis, whereas the specific mechanism regulating ferroptosis remains to be elucidated. The LO2 liver cell injury...