Overexpression of miR-204-5p Alleviates Osteogenic Differentiation and Calcification of Human Aortic Vascular Smooth Muscle Cells by Targeting Calcium/Calmodulin-dependent Protein Kinase 1 [0.03%]
miR-204-5p过表达通过靶向钙/钙调素依赖型蛋白激酶I缓解人主动脉血管平滑肌细胞的成骨分化及矿化作用
Chunli Wang,Mingzhi Xu,Yafei Bai et al.
Chunli Wang et al.
Vascular calcification (VC), a major complication in chronic kidney disease (CKD), is predominantly driven by osteoblastic differentiation. Recent studies have highlighted the crucial role of microRNAs in CKD's pathogenesis. Here, our resea...
Association between Uterine Adenomyosis and Infertility: Role of Axonemal Alteration in Apical Endometria [0.03%]
子宫腺肌症与不孕之间的联系：顶浆端粘附蛋白轴丝改变的作用
Khaleque N Khan
Khaleque N Khan
Uterine adenomyosis is an estrogen-dependent chronic inflammatory condition and may cause painful symptoms, abnormal uterine bleeding, and/or subfertility/infertility. It is characterized by the presence of endometrial glands and stroma wit...
Fatty Acid Binding Protein-4 Silencing Inhibits Ferroptosis to Alleviate Lipopolysaccharide-induced Injury of Renal Tubular Epithelial Cells by Blocking Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling [0.03%]
沉默脂肪酸结合蛋白-4通过阻断Janus激酶2/信号转导及转录激活因子3信号通路抑制铁死亡以缓解脂多糖诱导的肾小管上皮细胞损伤
Suo Xu,Jiye Luo,Yanli Wang et al.
Suo Xu et al.
Sepsis-induced kidney injury (SAKI) has been frequently established as a prevailing complication of sepsis which is linked to unfavorable outcomes. Fatty acid-binding protein-4 (FABP4) has been proposed as a possible target for the treatmen...
Tripartite Motif-containing Protein 11 Silencing Inhibits Proliferation and Glycolysis and Promotes Apoptosis of Esophageal Squamous Cell Carcinoma Cells by Inactivating Signal Transduction and Activation of Transcription Factor 3/c-Myc Signaling [0.03%]
三元基序含蛋白质11通过灭活信号转导及转录激活因子3/c-Myc通路抑制食管鳞癌细胞增殖、糖酵解及促进凋亡
Tingting Xuan
Tingting Xuan
Esophageal squamous cell carcinoma (ESCC) is a common type of human digestive tract cancer with poor survival. Tripartite motif-containing protein 11 (TRIM11) is an oncogene in certain cancers that can regulate glycolysis and signal transdu...
Acute Hyperoxia Improves Spinal Cord Oxygenation and Circulatory Function Following Cervical Spinal Cord Injury in Rats [0.03%]
急性高氧可改善颈椎脊髓损伤大鼠脊髓氧合及循环功能
Yen-Ting Lin,Elisa J Gonzalez-Rothi,Kun-Ze Lee
Yen-Ting Lin
Spinal cord injury is associated with spinal vascular disruptions that result in spinal ischemia and tissue hypoxia. This study evaluated the therapeutic efficacy of normobaric hyperoxia on spinal cord oxygenation and circulatory function a...
Athena Hsu Li,Yi-Ying Kuo,Shi-Bing Yang et al.
Athena Hsu Li et al.
As obesity has raised heightening awareness, researchers have attempted to identify potential targets that can be treated for therapeutic intervention. Focusing on the central nervous system (CNS), the key organ in maintaining energy balanc...
Sheng-Feng Tsai,Yu-Min Kuo
Sheng-Feng Tsai
Oxytocin (OXT), a neuropeptide originating from the hypothalamus and traditionally associated with peripheral functions in parturition and lactation, has emerged as a pivotal player in the central regulation of the autonomic nervous system ...
Effects of Arsenic-induced Diabetic Vascular Diseases through Mitogen-activated Protein Kinase Signaling Pathway: In vitro and In vivo Studies [0.03%]
砷通过活化丝裂原活化蛋白激酶信号途径诱导糖尿病血管病变的机制研究：体内外实验研究
Arsenic (As) is an environmental pollutant that causes endocrine disruption. Diabetes increases the risk of Blackfoot disease, which is a peripheral artery disease caused by chronic exposure to As through drinking water in Taiwan and Bangla...