Liquid biopsy for monitoring minimal residual disease in localized and locally-advanced non-small cell lung cancer after radical-intent treatment [0.03%]
局部和局部晚期非小细胞肺癌根治性治疗后通过液体活检监测微小残留病灶
Héctor Aguilar,Belén López-Roldán,Anna Vilalta-Lacarra et al.
Héctor Aguilar et al.
Blood-based biomarkers investigation does not require invasive tissue biopsies and may explore diverse tumoral components such as proteins, microRNAs, circulating tumor cells, ctDNA, and exosomes and may better reflect tumor molecular heter...
In vitro size-selection of short circulating tumor DNA fragments from late-stage lung cancer patients enhance the detection of mutations and aneuploidies [0.03%]
晚期肺癌患者循环肿瘤DNA短片段的体外筛选可增强对突变和非整倍体的检测能力
Christoffer Trier Maansson,Louise Skov Thomsen,Laura Stokkebro et al.
Christoffer Trier Maansson et al.
Introduction: Recent studies have demonstrated differences between the fragment length profiles of cell-free DNA (cfDNA) from cancer patients and healthy individuals. This has led to the development of in vitro size-selec...
Technical evaluation of a novel digital PCR platform for detecting EGFR/KRAS mutations in NSCLC archived plasma specimens [0.03%]
新型数字PCR平台检测非小细胞肺癌存档血浆样本中的EGFR/KRAS突变的技术评估
Claudia Scimone,Francesco Pepe,Gianluca Russo et al.
Claudia Scimone et al.
Introduction: KRAS p.G12C hot spot mutations has rapidly modified diagnostic algorithm for lung cancer patients electing Non-Small Cell Lung Cancer (NSCLC) patients to target treatment. As regards, patients that harbor th...
Shivani Ravipati,Arghya Nath,Sumitaksha Banerjee et al.
Shivani Ravipati et al.
Recent advances in cancer treatment emphasize the pivotal role of extracellular vesicles (EVs), especially exosomes (a subpopulation of EVs, originating from endosomes). Exosomes are signaling molecules in the cellular system. Its molecular...
Clinical significance of genomic sequencing of circulating tumour cells (CTCs) in cancer [0.03%]
循环肿瘤细胞基因测序在癌症中的临床意义
Abdul Auwal,M Matakabbir Hossain,Tasfik Ul Haque Pronoy et al.
Abdul Auwal et al.
Circulating tumour cell (CTC), a rare subpopulations of tumour cells, plays a significant role in cancer metastasis and recurrence. The current review focuses on information of CTCs detection, enrichment, genome sequencing and investigating...
Nanobiotechnology: A smart platform of the future transform liquid biopsy era [0.03%]
纳米生物技术：改造液体活检时代的未来智能平台
Srijan Goswami,Palas Samanta,Manab Deb Adhikari
Srijan Goswami
Cancer is the leading cause of death worldwide. The most complicated fact about this disease is early diagnosis. Treatment at advanced stages of the disease is extremely challenging. We need an early cancer detection method. Nanotechnology-...
Clinical application of liquid biopsy genomic profiling in NSCLC: Asian perspectives [0.03%]
液体活检基因谱在非小细胞肺癌临床应用中的亚洲视角
Molly S C Li,Kevin K S Mok,Landon L Chan et al.
Molly S C Li et al.
Molecular profiling is essential for treatment of patients with advanced non-small cell lung cancer. Extensive evidence supports the clinical application of liquid biopsy in molecular profiling and thus has been incorporated into multiple i...
Plasma cell-free RNA PD-L1 or tissue PD-L1 protein expression and outcomes with first-line immunotherapy in metastatic non-small cell lung cancer [0.03%]
转移性非小细胞肺癌一线免疫治疗中血浆游离RNA PD-L1或组织PD-L1蛋白表达与结果的关系
Paul R Walker,Sriraksha Jayananda,Melisa Pasli et al.
Paul R Walker et al.
Background: Tissue programmed death ligand-1 (PD-L1) protein expression is associated with immune checkpoint inhibitor (ICI) treatment benefit in metastatic non-small cell lung cancer (NSCLC). However, tissue PD-L1 protei...
Clinical Impact of Multi-omics profiling of extracellular vesicles in cancer Liquid Biopsy [0.03%]
癌症液体活检中外泌体多组学分析的临床影响
Mrunal Kulkarni,Rishav Kar,Srestha Ghosh et al.
Mrunal Kulkarni et al.
Extracellular vesicles (EVs) are the cell's secreted component. It is majorly classified into microvesicles, apoptotic bodies, and exosomes. Exosomes play a significant role in cancer development and progression. Its molecular signature (DN...
Roles of Tumor-Educated Platelets (TEPs) in the biology of Non-Small Cell Lung Cancer (NSCLC): A systematic review. "Re-discovering the neglected biosources of the liquid biopsy family" [0.03%]
肿瘤教育血小板（TEP）在非小细胞肺癌（NSCLC）生物学中的作用：对液体活检家族中被忽视的生物来源的“重新发现”的系统性回顾。
Andrea Gottardo,Valerio Gristina,Alessandro Perez et al.
Andrea Gottardo et al.
Due to their interactions with the neoplasm, platelets undergo various proteomic and transcriptomic modifications, resulting in the development of what is known as the "Tumor-Educated Platelets (TEPs) phenotype". Consequently, in addition t...