The role of molecular biomarkers in the diagnosis, prognosis, and treatment stratification of oral squamous cell carcinoma: A comprehensive review [0.03%]
分子生物标志物在口腔鳞状细胞癌的诊断，预后和治疗分层中的作用：全面综述
Saravanan Ravindran,Srinivasan Ranganathan,Karthikeyan R et al.
Saravanan Ravindran et al.
One of the most common cancers targeting the area of the head and neck is oral squamous cell carcinoma (OSCC), carrying a heavy global health cost. With a high incidence of metastasis and recurrence, the outlook for OSCC remains dismal desp...
Potential applications of gene expression profiles obtained from circulating extracellular vesicles in breast cancer [0.03%]
循环胞外囊泡获得的基因表达谱在乳腺癌中的潜在应用
Aritra Gupta,Siddharth Bhardwaj,Sayan Ghorai et al.
Aritra Gupta et al.
Background: Liquid biopsy-based biomarkers offer several advantages since they are minimally invasive, can be useful in longitudinal monitoring of the disease and have higher patient compliance. We describe a protocol usi...
Jessica Gasparello,Carlotta Ceccon,Valentina Angerilli et al.
Jessica Gasparello et al.
Circulating tumor DNA (ctDNA) is nowadays considered a robust source to search for druggable tumoral genetic alterations, and in some specific settings liquid biopsy (LB) is already part of the diagnostics scenario and it has successfully i...
Cell-free DNA as a complementary diagnostic tool for neglected tropical diseases towards achieving the WHO NTDs elimination by 2030 [0.03%]
细胞外DNA作为被忽视的热带疾病的互补诊断工具以实现世界卫生组织2030年消除NTDs的目标
Priscilla Osei-Poku,Lucienne Tritten,Fatima Fordjour et al.
Priscilla Osei-Poku et al.
Neglected Tropical Diseases (NTDs) continue to ravage the poorest regions of the world, with over 600 million people being affected in Sub-Saharan Africa. The global burden of NTDs within these regions is staggering, particularly post-COVID...
Cancer in a drop: Liquid biopsy highlights from San Antonio Breast Cancer Symposium (SABCS) 2024 [0.03%]
一滴中的癌症：圣安东尼奥乳腺癌 symposium (SABCS) 2024 液体活检亮点
Letizia Pontolillo,Mohamed A Gouda,Konstantinos Venetis et al.
Letizia Pontolillo et al.
Liquid biopsy into the clinics: Current evidence and future perspectives [0.03%]
液态活检在临床中的应用：当前的证据和未来的展望
Myrto Boukovala,C Benedikt Westphalen,Victoria Probst
Myrto Boukovala
As precision oncology has become a major part of the treatment landscape in oncology, liquid biopsies have developed as a particularly powerful tool as it surmounts several limitations of traditional tissue biopsies. These biopsies involve ...
NGS detection of gene rearrangements and METexon14 mutations in liquid biopsy of advanced NSCLC patients: A study of two Italian centers [0.03%]
晚期非小细胞肺癌患者液体活检中基因重排和MET外显子14突变的NGS检测：两个意大利中心的研究
Michela Verzè,Andrea Boscolo Bragadin,Roberta Minari et al.
Michela Verzè et al.
Introduction: ctDNA is a useful tool for NGS molecular profiling in advanced NSCLC patients. Its clinical applicability in patients with gene rearrangements is still limited due to a lower detection rate of these types of...
Putting comprehensive genomic profiling of ctDNA to work: 10 proposed use cases [0.03%]
全面基因组分析ctDNA的十种实际应用提案
Aakash Desai,Lincoln W Pasquina,Candice Nulsen et al.
Aakash Desai et al.
Liquid biopsy profiling of circulating tumor DNA (ctDNA) has become established as a compelling, pragmatic diagnostic in the care of cancer patients and is now endorsed by multiple cancer care guidelines. Moreover, ctDNA profiling technolog...
Sylvie Devalle,Veronica Aran,Cesar de Souza Bastos Júnior et al.
Sylvie Devalle et al.
Colon cancer (CC) is one of the most frequent cancers worldwide being responsible for over 500 thousand deaths in 2022. Its financial and human burden is expected to increase in the next decades accompanying the growing and aging of the glo...
Role of cell-free DNA and extracellular vesicles for diagnosis and surveillance in patients with glioma [0.03%]
无细胞DNA和胞外囊泡在胶质瘤患者诊断和监测中的作用
Busra Karacam,Elif Burce Elbasan,Imran Khan et al.
Busra Karacam et al.
Objectives: Liquid biopsy can be used to make the diagnosis, to screen treatment response, and to predict the prognosis. Extracellular vesicles (EVs) and cell-free DNA (cfDNA) sources are used as liquid biopsy biomarkers ...