Protocol and Statistical Analysis Plan for the Mode of Ventilation During Critical Illness (MODE) Trial [0.03%]
重症监护中通气模式研究（模式研究）方案与统计分析计划
Kevin P Seitz,Bradley D Lloyd,Li Wang et al.
Kevin P Seitz et al.
Background: For every critically ill adult receiving invasive mechanical ventilation, clinicians must select a mode of ventilation. The mode of ventilation determines whether the ventilator directly controls the tidal vol...
Acute Respiratory Failure From Early Pandemic COVID-19: Noninvasive Respiratory Support vs Mechanical Ventilation [0.03%]
早发型新冠肺炎急性呼吸衰竭的非侵入式呼吸支持与有创机械通气比较
Julia M Fisher,Vignesh Subbian,Patrick Essay et al.
Julia M Fisher et al.
Background: The optimal strategy for initial respiratory support in patients with respiratory failure associated with COVID-19 is unclear, and the initial strategy may affect outcomes. ...
Evidence Synthesis of Outcomes of Extracorporeal Membrane Oxygenation for Life-Threatening Asthma Exacerbations [0.03%]
危重哮喘急性发作体外膜肺氧合疗效的证据综合
Burton H Shen,Anica C Law,Kevin C Wilson
Burton H Shen
Variation in Sedative and Analgesic Use During the COVID-19 Pandemic and Associated Outcomes [0.03%]
新冠肺炎疫情下镇静剂和止痛药使用的变化及其相关结局
Justin M Rucci,Anica C Law,Scott Bolesta et al.
Justin M Rucci et al.
Background: Providing analgesia and sedation is an essential component of caring for many mechanically ventilated patients. The selection of analgesic and sedative medications during the COVID-19 pandemic, and the impact ...
Characterizing Cardiac Function in ICU Survivors of Sepsis: A Pilot Study Protocol [0.03%]
重症监护病房幸存的感染患者的 cardiac function 研究协议：一项试点研究
Kevin Garrity,Christie Docherty,Kenneth Mangion et al.
Kevin Garrity et al.
Background: Sepsis is one of the most common reasons for ICU admission and a leading cause of mortality worldwide. More than one-half of survivors experience significant physical, psychological, or cognitive impairments, ...
Use of Inhaled Epoprostenol in Patients With COVID-19 Receiving Humidified, High-Flow Nasal Oxygen Is Associated With Progressive Respiratory Failure [0.03%]
吸入伊洛前列素用于接受湿化高流量鼻导管吸氧的COVID-19患者的呼吸功能障碍进展相关
Andrew P Michelson,Patrick G Lyons,Nguyet M Nguyen et al.
Andrew P Michelson et al.
Background: The clinical benefit of using inhaled epoprostenol (iEpo) through a humidified high-flow nasal cannula (HHFNC) remains unknown for patients with COVID-19. ...
A Least Absolute Shrinkage and Selection Operator-Derived Predictive Model for Postoperative Respiratory Failure in a Heterogeneous Adult Elective Surgery Patient Population [0.03%]
异质性成人择期手术患者术后呼吸衰竭的预测模型——源于最小绝对收缩和选择算子的研究
Jacqueline C Stocking,Sandra L Taylor,Sili Fan et al.
Jacqueline C Stocking et al.
Background: Postoperative respiratory failure (PRF) is associated with increased hospital charges and worse patient outcomes. Reliable prediction models can help to guide postoperative planning to optimize care, to guide ...
Trajectories of Host-Response Subphenotypes in Patients With COVID-19 Across the Spectrum of Respiratory Support [0.03%]
接受不同程度呼吸支持的COVID-19患者的宿主反应亚表型轨迹研究
Michael Lu,Callie Drohan,William Bain et al.
Michael Lu et al.
Background: Hospitalized patients with severe COVID-19 follow heterogeneous clinical trajectories, requiring different levels of respiratory support and experiencing diverse clinical outcomes. Differences in host immune r...
Factors Influencing Influenza and COVID-19 Vaccine Decision-Making in the Post-ICU Period: A Secondary Analysis [0.03%]
重症监护后期流感和COVID-19疫苗决策的影响因素：二次分析
Stacey J Carter,Jana Lauderdale,Joanna L Stollings et al.
Stacey J Carter et al.
Background: The introduction of COVID-19 vaccines exposed volatility and hesitancy around vaccines. Some health care models, including ICU recovery clinics (ICU-RCs), are structured to provide vaccine counseling. However,...
Ex Vivo Endotoxin Stimulation of Blood for Predicting Survival in Patients With Sepsis: A Systematic Review [0.03%]
血液体外内毒素刺激用于预测脓毒症患者存活率的系统性回顾
Jonathan Wheelwright,E Scott Halstead,Amy Knehans et al.
Jonathan Wheelwright et al.
Background: Sepsis is a syndrome characterized by host immune dysfunction, with the extent of immunoparalysis differing among patients. Lipopolysaccharide (LPS) is used commonly to assess the immune function of critically...