Cancellation and Resumption of Elective Surgeries Over Time Across a National Sample of US Hospitals During the COVID-19 Pandemic [0.03%]
美国医院在COVID-19大流行期间择期手术的取消和恢复：基于全国范围住院医疗机构的分析
Kelly C Vranas,Deena Kelly Costa,Billie S Davis et al.
Kelly C Vranas et al.
Understanding Provider-Level Variation in Clinical Practice: A Longitudinal Survey of Corticosteroid Use in Septic Shock [0.03%]
纵向调查Septic Shock患者使用皮质类固醇的情况以了解提供者在临床实践中的差异性
Kanupriya Soni,Leigh A Bukowski,Billie S Davis et al.
Kanupriya Soni et al.
Background: Clinician practice patterns vary widely in the ICU, particularly in the context of therapies with moderate-quality evidence. A better understanding of the psychological factors underlying provider-level practi...
Association of Central Nervous System-Related Biomarkers With Hospital Delirium in Patients With Respiratory Failure in the ICU [0.03%]
ICU呼吸衰竭患者中枢神经系统相关生物标志物与医院内谵妄的关系研究
Andrew T Pham,Ryan A Peterson,Suzanne Slaughter et al.
Andrew T Pham et al.
Background: Delirium commonly occurs in critical illness and is associated with significant morbidity and mortality. Although risk reduction measures can mitigate the risk of delirium, identifying patients in whom deliriu...
Anti-CD14 treatment in patients with severe COVID-19: Clinical and biological effects in a Phase 2 randomized open-label adaptive platform clinical trial [0.03%]
抗CD14治疗重度新冠肺炎患者的临床和生物学效应：一项二期开放性适应性平台临床试验的结果
F Linzee Mabrey,Thomas R Martin,Carolyn S Calfee et al.
F Linzee Mabrey et al.
Background and research question: CD14-dependent innate immunity contributes to poor outcomes in COVID-19 pneumonia. We tested the clinical and biological efficacy of a blocking monoclonal antibody to CD14 (IC14) for trea...
Derivation and Validation of a Clinical and Endothelial Biomarker Risk Model to Predict Persistent Pediatric Sepsis-Associated Acute Respiratory Dysfunction [0.03%]
一种临床和内皮生物标志物风险模型的推导与验证 可以预测儿童持续性脓毒症相关急性呼吸功能障碍
James G Williams,Jane E Whitney,Scott L Weiss et al.
James G Williams et al.
Background: Sepsis-associated ARDS results in high morbidity and mortality in children. However, heterogeneity among patients makes identifying those at risk of persistent acute respiratory dysfunction challenging. Endoth...
A Descriptive Qualitative Study of Religion and Spirituality's Role in Critical Illness Decision-Making Among Black and White Family Caregivers [0.03%]
宗教和精神在黑人和白人家庭护工重症监护决策中作用的描述性定性研究
Oluwatumilara F Akeke,Dingyue Wang,Deborah Ejem et al.
Oluwatumilara F Akeke et al.
Background: Spiritual beliefs and spiritual support from clinicians can affect medical decision-making and coping during times of serious illness. Researc...
Acetaminophen and Clinical Outcomes in Sepsis: A Retrospective Propensity Score Analysis of the Ibuprofen in Sepsis Study [0.03%]
acetamin酚在脓毒症临床疗效的回顾性倾向评分分析：一项ibuprofen治疗脓毒症的研究
Sarah N Obeidalla,Gordon R Bernard,Lorraine B Ware et al.
Sarah N Obeidalla et al.
Background: The Ibuprofen in Sepsis Study (ISS) randomized trial found no difference in duration of shock, ARDS, or mortality with ibuprofen treatment for sepsis. However, higher use of acetaminophen, a known hemoprotein ...
Feasibility of In-Hospital Administration of a Tool to Predict Persistent Post-ICU Functional Impairment Among Older ICU Survivors: A Pilot Study [0.03%]
预测老年ICU幸存者出院后长期功能障碍的ICU内工具使用的可行性：一项试点研究
Julia A Stevenson,Terrence E Murphy,Baylah Tessier-Sherman et al.
Julia A Stevenson et al.
Background: A recent international consensus conference called for the development of risk prediction models to identify ICU survivors at increased risk of each of the post-ICU syndrome domains. We previously developed an...
Outcome Measures to Evaluate Functional Recovery in Survivors of Respiratory Failure: A Scoping Review [0.03%]
评估呼吸衰竭幸存者功能恢复的结局指标：系统综述
Kaitlyn Parrotte,Luz Mercado,Hope Lappen et al.
Kaitlyn Parrotte et al.
Background: Respiratory failure is a life-threatening condition affecting millions of individuals in the United States annually. Survivors experience persistent functional impairments, decreased quality of life, and cogni...
Predictors of Medical Mistrust Among Surrogate Decision-Makers of Patients in the ICU at High Risk of Death: A Pilot Study [0.03%]
重症监护室高危患者委托决定人的医疗不信任预测因素：一项试点研究
Scott T Vasher,Jeff Laux,Shannon S Carson et al.
Scott T Vasher et al.
Background: Medical mistrust may worsen communication between ICU surrogate decision-makers and intensivists. The prevalence of and risk factors for medical mistrust among surrogate decision-makers are not known. ...