Commentary on the "Relationship between visceral obesity and prognosis in patients with stage IVB cervical cancer receiving radiotherapy and chemotherapy" [0.03%]
有关盆腔器官肥胖与接受放化疗的IVB期宫颈癌患者预后关系的述评
Gnanaprakash Jeyaraj
Gnanaprakash Jeyaraj
Breast cancer risk associated with BRCA1 and BRCA2 pathogenic variants in the Eastern Chinese population [0.03%]
与中国东部人群BRCA1和BRCA2致病突变相关的乳腺癌风险
Sanjian Yu,Xia Qiu,Zezhou Wang et al.
Sanjian Yu et al.
Background: Population-based penetrance studies of breast cancer gene 1/2 (BRCA1/2) pathogenic or likely pathogenic (P/LP) variants in the Eastern Chinese population are currently lacking; thus, we aimed to investigate th...
Lei Liu,Peng Yuan,Xue Wang
Lei Liu
Dynamics of epithelial-mesenchymal plasticity driving cancer drug resistance [0.03%]
上皮间质可塑性驱动癌症药物耐药性的动态过程
Rashmi Bangarh,Reena V Saini,Adesh K Saini et al.
Rashmi Bangarh et al.
Epithelial-mesenchymal transition (EMT) promotes several cancers by increasing tumor cell motility, disrupting epithelial cell phenotypes, apical-basal polarity, and intracellular connections, and enhancing tumor resistance to immunotherapy...
Nomogram for predicting the risk and prognosis of lung metastasis of four subtypes of breast cancer: A population-based study from SEER [0.03%]
基于SEER的流行病学研究建立四种类型乳腺癌肺转移风险和预后的列线图预测模型
Yuanfang Xin,Guoxin Zhang,Qiuxia Dong et al.
Yuanfang Xin et al.
Background: Breast cancer (BC) is the most diagnosed cancer worldwide, and patients' survival decreases with metastasis. We conducted a retrospective study using data derived from the Surveillance, Epidemiology, and End R...
A Bayesian network meta-analysis of EGFR-tyrosine kinase inhibitor treatments in patients with EGFR mutation-positive non-small cell lung cancer [0.03%]
表皮生长因子受体酪氨酸激酶抑制剂治疗表皮生长因子受体突变阳性非小细胞肺癌的贝叶斯网络meta分析
Jianqiong Yin,Jing Huang,Min Ren et al.
Jianqiong Yin et al.
Background: To date, no direct comparisons have been performed to compare the effectiveness of all epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) against EGFR mutation-positive non-small cell lung...
Cardiotoxicity in platinum-based chemotherapy: Mechanisms, manifestations, and management [0.03%]
基于铂类的化疗引起的心脏毒性：机制、表现和管理措施
Betty Rachma,Merlyna Savitri,Henry Sutanto
Betty Rachma
Platinum-based chemotherapy, a cornerstone in the treatment of various malignancies, is often limited by its potential cardiotoxic effects. Understanding these effects is crucial for optimizing patient outcomes and guiding treatment decisio...
Risk of autoimmunity, cancer seeding, and adverse events in human trials of whole-tissue autologous therapeutic vaccines [0.03%]
关于自体组织治疗性疫苗人体试验的自身免疫、癌症种植和不良事件风险
Garrett Gianneschi,Anthony Scolpino,James Oleske
Garrett Gianneschi
Background: Whole-tissue autologous therapeutic vaccines (WATVs) are a form of cancer immunotherapy that use a patient's own pathological tissue. Concerns exist regarding the potential of WATVs to induce autoimmunity or t...
Exploring the significance of extracellular vesicles: Key players in advancing cancer and possible theranostic tools [0.03%]
探索细胞外囊泡的意义：推进癌症研究及可能的诊疗工具的重要角色
Bhaumik Patel,Shreyas Gaikwad,Sahdeo Prasad
Bhaumik Patel
Metastasis remains a critical challenge in cancer treatment and the leading cause of cancer-related mortality. Ongoing research has demonstrated the key role of extracellular vesicles (EVs) in facilitating communication between distant orga...