Exploring marine-derived compounds as potential anti-cancer agents: Mechanisms and therapeutic implications [0.03%]
海洋衍生化合物的抗癌潜力：机制和治疗意义研究
Nagaraju Bandaru,Yash Pramod Patil,Sumit Dilip Ekghara et al.
Nagaraju Bandaru et al.
Marine-derived compounds have emerged as a promising frontier in cancer research due to their remarkable structural diversity and broad-spectrum bioactivities. The marine environment, encompassing diverse organisms (e.g., sponges, algae, tu...
C-X-C chemokine receptor type 4 (CXCR4) antagonism in precision oncology: Clinical applications and future directions [0.03%]
精准肿瘤学中C-X-C趋化因子受体类型4（CXCR4）拮抗的应用及未来方向
Aswini Rajendran,Veronica Elumalai,Saranya Balasubramaniyam et al.
Aswini Rajendran et al.
Physiologically, the C-X-C chemokine receptor type 4 (CXCR4) signalling pathway regulates key aspects of tumor behavior (growth, metastasis, and immune evasion) and modulates immune system function. Anticancer researchers have identified pe...
Targeting immune checkpoint therapy: The role of manganese in tumor immunotherapy [0.03%]
靶向免疫检查点治疗：锰在肿瘤免疫治疗中的作用
Xingyao Lyu,Bixia Li,Zhijie Lin
Xingyao Lyu
Cancer immunotherapy has emerged as a promising complement to traditional treatments such as radiotherapy and chemotherapy. Although conventional therapies remain central to cancer management, the potential of immunotherapy is increasingly ...
Investigating hypoxia-inducible factor signaling in cancer: Mechanisms, clinical implications, targeted therapeutic strategies, and resistance [0.03%]
癌症中缺氧诱导因子信号通路的研究：机制、临床意义、靶向治疗策略及耐药性
Abdul Halim Shaikat,S M Asadul Karim Azad,Md Azizur Rahman Tamim et al.
Abdul Halim Shaikat et al.
Hypoxia, a hallmark of the tumor microenvironment (TME), drives cancer progression through immune modulation, angiogenesis promotion, metabolic reprogramming, and uncontrolled cell proliferation. This review explores the diverse functions o...
Survival outcomes associated with surgery, radiotherapy, and chemotherapy in metastatic vulvar cancer [0.03%]
转移性外阴癌手术、放疗和化疗与生存结果相关的联系
Md Faiazul Haque Lamem,Muaj Ibne Sahid
Md Faiazul Haque Lamem
Right atrial intimal sarcoma with liver metastasis: A case report and literature review [0.03%]
右房内膜肉瘤合并肝转移的病例报告及文献复习
Jiaen You,Zebing Liu,Kang He
Jiaen You
Primary cardiac tumors are rare and often present diagnostic challenges due to their non-specific symptoms and imaging characteristics. In this report, we present a case of right atrial intimal sarcoma (IS) with liver metastasis. A 49-year-...
Biplab Adhikari
Biplab Adhikari
•Yogurt consumption is linked to 20-40% lower colorectal cancer risk, especially proximal colon tumors with high Bifidobacterium levels.•Probiotics modulate gut microbiota, reduce inflammation, and produce protective metabolites against c...
Reduced cytomegalovirus reactivation and viremia without increasing GVHD after URD-PBSCT: A prospective study using targeted ATG dosing strategy [0.03%]
一种减少CMV再活化和血症而不增加GVHD的非清髓性异基因移植方案：靶向使用ATG的前瞻性研究
Sheng Chen,Lu Wang,Songhua Luan et al.
Sheng Chen et al.
Background: Anti-thymocyte globulin (ATG) is widely used in allogeneic hematopoietic stem cell transplantation (allo-HCT) to prevent severe graft-versus-host disease (GVHD) and graft failure. Insufficient ATG exposure may...
Improving research transparency: An interpretation of the updated consolidated standards of reporting trials 2025 guideline from the perspective of clinical trials in oncology [0.03%]
提高研究透明度——从肿瘤临床试验视角解读CONSORT 2025更新指南
Yaguang Peng,Peng Lyu,Xiaoxia Peng
Yaguang Peng
Pan-cancer gene signature analysis of macrophage polarization and compound prediction for reprogramming tumor-associated macrophages toward M1-like macrophages [0.03%]
泛癌症的基因签名分析巨噬细胞极化及用于将肿瘤相关巨噬细胞重编程为M1样巨噬细胞的化合物预测
Xiaojing Liu,Cheng Liu,Yuting Jin et al.
Xiaojing Liu et al.
Background: Resting tumor-associated macrophages (TAMs) are stimulated by the tumor microenvironment and can be primarily polarized into two subtypes: M1-and M2-like. M1-like TAMs promote inflammation and eradicate tumor ...