Balancing Therapeutic Efficacy and Safety of MDMA and Novel MDXX Analogues as Novel Treatments for Autism Spectrum Disorder [0.03%]
MDMA和新型MDXX衍生物在自闭症光谱障碍治疗中疗效与安全性的平衡
Harpreet Kaur,Sedat Karabulut,James W Gauld et al.
Harpreet Kaur et al.
Autism spectrum disorder (ASD) encompasses a range of neurodevelopmental syndromes diagnostically characterized by deficits in social communication and social interaction and repetitive, inflexible patterns of behaviors, interests, and thou...
Psychedelic Commercialization: A Wide-Spanning Overview of the Emerging Psychedelic Industry [0.03%]
迷幻药商业化：对新兴迷幻药行业的广泛概述
Jacob S Aday,Brian S Barnett,Dan Grossman et al.
Jacob S Aday et al.
Background: In the wake of positive clinical trial outcomes of psychedelic-assisted psychotherapy for the treatment of various psychiatric disorders, there has been an influx of financial investment into psychedelic drug ...
Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psychedelic Med 2023;1(1):18-26; doi: 10.1089/psymed.2022.0002 [0.03%]
对Nayak等人关于Psilocybin与Escitalopram治疗抑郁症的试验的贝叶斯重新分析的更正《Psychedelic Med》2023;1(1):18-26; doi: 10.1089/psymed.2022.0002
[This corrects the article DOI: 10.1089/psymed.2022.0002.]. Copyright 2024, Mary Ann Liebert, Inc., publishers.
Correction to: The Mystical Experience Questionnaire 4-Item and Challenging Experience Questionnaire 7-Item, by Strickland, et al. Psychedelic Medicine 2024;2(1):33-43; doi: 10.1089/psymed.2023.0046 [0.03%]
对《神秘体验问卷4项和挑战性体验问卷7项》一文的更正，作者：Strickland等人. Psychedelic Medicine 2024;2(1):33-43; doi: 10.1089/psymed.2023.0046
[This corrects the article DOI: 10.1089/psymed.2023.0046.]. Copyright 2024, Mary Ann Liebert, Inc., publishers.
General Anesthesia Occludes Ketamine's Antidepressant Response in a Rodent Model of Chronic Stress [0.03%]
全身麻醉阻断氯胺酮在慢性应激小鼠模型中的抗抑郁反应
Daniel Markman,Andrzej Z Wasilczuk,Joseph Michael Cichon
Daniel Markman
Introduction: Psychedelic-induced experiences are thought to play an important role in the therapeutic actions of rapid-acting antidepressants. General anesthesia is one scenario in which patients can be rendered unconsci...
Divergent Effects of Ketamine and the Serotoninergic Psychedelic 2,5-Dimethoxy-4-Iodoamphetamine on Hippocampal Plasticity and Metaplasticity [0.03%]
氯胺酮和血清素致幻剂2,5-二甲氧基-4-碘苯胺对海马可塑性和元可塑性产生不同的影响
Zarmeen Zahid,Ziyad W Sultan,Bryan M Krause et al.
Zarmeen Zahid et al.
Introduction: Serotonergic psychedelics and ketamine produce rapid and long-lasting symptomatic relief in multiple psychiatric disorders. Evidence suggests that despite having distinct molecular targets, both drugs may ex...
A Multimodal Preclinical Assessment of MDMA in Female and Male Rats: Prohedonic, Cognition Disruptive, and Prosocial Effects [0.03%]
一种评估 MDMA 对雌雄大鼠多模态预临床效应的方法：促进快感、认知紊乱和社交积极作用
Abshir S Adam,Kayleigh S LaMalfa,Yasaman Razavi et al.
Abshir S Adam et al.
Background: Frontline antidepressants such as selective serotonin reuptake inhibitors (SSRIs) leave many patients with unmet treatment needs. Moreover, even when SSRIs reduce depressive symptoms, anhedonia, the loss of pl...
Double-Blind Comparison of the Two Hallucinogens Dextromethorphan and Psilocybin: Experience-Dependent and Enduring Psychological Effects in Healthy Volunteers [0.03%]
两种致幻剂右美沙芬和裸盖菇素的双盲比较：健康志愿者的经验依赖性和持久性心理影响
David S Mathai,Samantha Hilbert,Nathan D Sepeda et al.
David S Mathai et al.
Rationale: N-methyl-D-aspartate receptor-mediated dissociatives and serotonergic hallucinogens are being increasingly used in therapeutic interventions that involve nonordinary states of consciousness and may represent a ...
Applying Key Lessons from the Hospice and Palliative Care Movement to Inform Psychedelic-Assisted Therapy [0.03%]
汲取临终关怀和姑息治疗运动中的关键经验以指导迷幻药物辅助疗法的发展
Megan Miller,William E Rosa,Alden Doerner Rinaldi et al.
Megan Miller et al.
Background: Psychedelic-assisted therapy (PAT) has re-emerged as a promising intervention for addressing mental health conditions and existential concerns. Despite growing enthusiasm, PAT may be difficult to integrate int...
Tabernanthalog Reduces Motivation for Heroin and Alcohol in a Polydrug Use Model [0.03%]
_tabernanthalog在多药滥用模型中减少海洛因和酒精的求食行为
Jasper A Heinsbroek,Giuseppe Giannotti,Joel Bonilla et al.
Jasper A Heinsbroek et al.
Background: The potential use of psychedelic drugs as therapeutics for neuropsychiatric disorders has been limited by their hallucinogenic properties. To overcome this limitation, we developed and characterized tabernanth...