Identifying stationary microbial interaction networks based on irregularly spaced longitudinal 16S rRNA gene sequencing data [0.03%]
基于不规则纵向16S rRNA基因测序数据识别稳态微生物互作网络
Jie Zhou,Jiang Gui,Weston D Viles et al.
Jie Zhou et al.
Introduction: The microbial interactions within the human microbiome are complex, and few methods are available to identify these interactions within a longitudinal microbial abundance framework. Existing methods typicall...
Diet-Microbiome Interactions Influence Lung Function in Chronic Obstructive Pulmonary Disease [0.03%]
肠道微生物与饮食的相互作用影响慢性阻塞性肺疾病的肺功能
Haowen Qiu,Rees Checketts,Mariah Kay Jackson et al.
Haowen Qiu et al.
Chronic Obstructive Pulmonary Disease (COPD) affects 30 million Americans. Previous epidemiologic work has shown that diet can impact pulmonary function in those with and without COPD. Diet is also a major driver of gut microbiome compositi...
Purified fibers in chemically defined synthetic diets destabilize the gut microbiome of an omnivorous insect model [0.03%]
化学定义的合成饮食中提纯的纤维会使一种杂食性昆虫模型的肠道微生物群失稳
Rachel Louise Dockman,Elizabeth A Ottesen
Rachel Louise Dockman
The macronutrient composition of a host's diet shapes its gut microbial community, with dietary fiber in particular escaping host digestion to serve as a potent carbon source for gut microbiota. Despite widespread recognition of fiber's imp...
Toll-like receptor 4 deletion partially protects mice from high fat diet-induced arterial stiffness despite perturbation to the gut microbiota [0.03%]
toll-like受体4缺失通过扰乱肠道菌群部分地保护小鼠免于高脂饮食引起的动脉硬化
Kayl E Ecton,Elliot L Graham,Briana D Risk et al.
Kayl E Ecton et al.
The present study aimed to determine the effects of toll-like receptor 4 (TLR4) deletion on high fat diet-induced aortic stiffness and gut microbiota alterations. We hypothesized that a high fat diet would result in perturbation of the gut ...
Treatment performance and microbial community structure in an aerobic granular sludge sequencing batch reactor amended with diclofenac, erythromycin, and gemfibrozil [0.03%]
添加双氯芬酸、红霉素和吉非罗齐的曝气颗粒污泥序批反应器处理性能及微生物群落结构研究
Kylie B Bodle,Rebecca C Mueller,Madeline R Pernat et al.
Kylie B Bodle et al.
This study characterizes the effects of three commonly detected pharmaceuticals-diclofenac, erythromycin, and gemfibrozil-on aerobic granular sludge. Approximately 150 μg/L of each pharmaceutical was fed in the influent to a sequencing bat...
Interactions between arsenic exposure, high-fat diet and NRF2 shape the complex responses in the murine gut microbiome and hepatic metabolism [0.03%]
砷暴露、高脂饮食和NRF2相互作用塑造小鼠肠道微生物组和肝脏代谢的复杂响应机制
Gabriele Schiro,Pengfei Liu,Matthew Dodson et al.
Gabriele Schiro et al.
Inorganic arsenic (iAs) exposure has been associated to various detrimental effects such as development of metabolic syndrome and type 2 diabetes via oxidative stress and induced prolonged activation of the NRF2 transcription factor. Such e...
Modulation of microbiome diversity and cytokine expression is influenced in a sex-dependent manner during aging [0.03%]
衰老过程中肠道微生物组多样性和细胞因子表达受性别影响而发生变化
Sarah E Webster,Duncan Vos,Thomas L Rothstein et al.
Sarah E Webster et al.
The microbiome and immune system have a unique interplay, which influences homeostasis within the organism. Both the microbiome and immune system play important roles in health and diseases of the aged including development of cancer, autoi...
Gut dysbiosis following organophosphate, diisopropylfluorophosphate (DFP), intoxication and saracatinib oral administration [0.03%]
有机磷化合物DFP中毒及口服saracatinib引起的肠道菌群失调
Meghan Gage,Akhil A Vinithakumari,Shankumar Mooyottu et al.
Meghan Gage et al.
Organophosphate nerve agents (OPNAs) act as irreversible inhibitors of acetylcholinesterase and can lead to cholinergic crisis including salivation, lacrimation, urination, defecation, gastrointestinal distress, respiratory distress, and se...
Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic asthma [0.03%]
基于肥胖性过敏哮喘小鼠模型的肠-肺轴元组学揭示与肺弹性增加相关的代谢网络及宿主-微生物互作机制
Victoria A Heinrich,Crystal Uvalle,Michelle L Manni et al.
Victoria A Heinrich et al.
Obesity and associated changes to the gut microbiome worsen airway inflammation and hyperresponsiveness in asthma. Obesogenic host-microbial metabolomes have altered production of metabolites that may influence lung function and inflammator...
Inulin supplementation prior to mild traumatic brain injury mitigates gut dysbiosis, and brain vascular and white matter deficits in mice [0.03%]
菊粉预处理通过减轻肠道菌群紊乱、脑血管和神经白质异常来缓解轻度颅脑损伤所致认知功能障碍小鼠模型的认知障碍
Lucille M Yanckello,Ya-Hsuan Chang,McKenna Sun et al.
Lucille M Yanckello et al.
Introduction: Mild traumatic brain injury (mTBI) has been shown to negatively alter bacterial diversity and composition within the gut, known as dysbiosis, in rodents and humans. These changes cause secondary consequences...