Gaps in the implementation of national core elements for sustainable antimicrobial use in the WHO-African region [0.03%]
非洲区域国家核心要素在可持续抗菌素使用实施中的缺口分析报告
Walter L Fuller,Aaron O Aboderin,Ali Yahaya et al.
Walter L Fuller et al.
Background: Antimicrobial resistance (AMR) has emerged as a leading global health and economic threat of the 21st century, with Africa bearing the greatest burden of mortality from drug-resistant infections. Optimization ...
Stephen Henry Gillespie
Stephen Henry Gillespie
Effects of age and pasture type on the concentration and prevalence of tetracycline and macrolide resistant Enterococcus species in beef cow-calf production system [0.03%]
年龄和放牧类型对牛肉生产体系中四环素和大环内酯耐药性肠球菌浓度和流行率的影响
Getahun E Agga,Hunter O Galloway,Annesly M P Netthisinghe
Getahun E Agga
Enterococci are a normal flora of the gastrointestinal tracts of humans and animals. Enterococci can also cause life-threatening nosocomial infections. Antimicrobial-resistant Enterococcus species have been reported in the feedlot and dairy...
Editorial: Preserving antibiotics: stewardship and effective treatment in low and middle income countries [0.03%]
论著：抗生素保藏：发展中世界的管理与有效治疗
Abdul Ghafur,Stephen H Gillespie
Abdul Ghafur
In vitro antimicrobial susceptibility of clinical isolates from adult and paediatric patients in Jordan: Antimicrobial Testing Leadership and Surveillance (ATLAS) 2010-2021 [0.03%]
2010-2021年期间约旦成人和儿童临床分离菌的体外抗菌药物敏感性：抗菌药物测试领导力与监测（ATLAS）
Dima Al Jammal,Julia Bachir,Jihane A Moussa et al.
Dima Al Jammal et al.
Objectives: To evaluate the in vitro antimicrobial susceptibilities of Gram-positive and Gram-negative isolates from patients in Jordan between 2010 and 2021, through the Antimicrobial Testing Leadership and Surveillance ...
Unguarded liabilities: Borrelia burgdorferi's complex amino acid dependence exposes unique avenues of inhibition [0.03%]
未被防护的脆弱性：复杂氨基酸需求揭示了伯氏疏螺旋体的独特抑制途径
Katrina J Holly,Arti Kataria,Daniel P Flaherty et al.
Katrina J Holly et al.
Recent reports from the Centers for Disease Control and Prevention approximate 500,000 cases of Lyme disease in the United States yearly, a significant economic burden on the healthcare system. The standard treatment for Lyme disease includ...
Mycobactin analogue interacting with siderophore efflux-pump protein: insights from molecular dynamics simulations and whole-cell assays [0.03%]
分子动力学模拟和全细胞试验揭示的一种结合铁载体流出泵蛋白的分枝菌酸类似物的相互作用机制
Mousumi Shyam,Abhishek Thakur,Caroline Velez et al.
Mousumi Shyam et al.
Introduction: In response to continued public health emergency of antimicrobial resistance (AMR), a significant key strategy is the discovery of novel mycobacterial efflux-pump inhibitors (EPIs) as potential adjuvants in ...
Examining pharmacoepidemiology of antibiotic use and resistance in first-line antibiotics: a self-controlled case series study of Escherichia coli in small companion animals [0.03%]
小型伴侣动物中大肠杆菌一線抗生素使用和抗藥性的 pharmacoepidemiology研究：自身對照病例系列研究
Olivia S K Chan,Wendy Wing Tak Lam,Tint Naing et al.
Olivia S K Chan et al.
Background: Clinicians need to prescribe antibiotics in a way that adequately treats infections, while simultaneously limiting the development of antibiotic resistance (ABR). Although there are abundant guidelines on how ...
Amy D Thompson,Desiree N Neville,Laura L Chapman et al.
Amy D Thompson et al.
Background: The 2018 Infectious Disease Committee of the American Academy of Pediatrics stated that up to 3 weeks or less of doxycycline is safe in children of all ages. Our goal was to examine trends in doxycycline treat...