2024 transplant AI symposium: key AI models shaping the future of transplant care [0.03%]
2024移植AI研讨会:塑造未来移植护理的关键人工智能模型
Annabel Koivu,Ghazal Azarfar,Saba Maleki et al.
Annabel Koivu et al.
Experts in transplantation medicine and AI innovation came together to showcase advancements in AI applications with the potential to improve transplant outcomes. Ethical deployment, consolidation of multimodal data and supporting clinical ...
Immunosuppressive and antiinfectious regimens in vascular composite allograft recipients-a systematic review [0.03%]
血管复合移植受者的免疫抑制和抗感染方案-系统性回顾研究
Leonard Knoedler,Tobias Niederegger,Thomas Schaschinger et al.
Leonard Knoedler et al.
Introduction: Vascularized composite allotransplantation (VCA) has achieved significant clinical success, but lifelong immunosuppression remains essential to prevent rejection. Despite potent regimens, including tacrolimu...
Importing pancreata for transplantation: a single-center experience across evolving allocation eras [0.03%]
供胰腺移植的引入:单一中心在分配体系变迁中的经验总结
Riccardo Tamburrini,Stacey Hidalgo,Glen Leverson et al.
Riccardo Tamburrini et al.
Recent changes to allocation systems have increased the geographic distribution of pancreas offers, often originating from outside a transplant center's donor service area or region. The impact of this wider sharing on outcomes remains unce...
The role of macrophages in the mitigation by decitabine of acute allograft rejection [0.03%]
地西他滨通过调节巨噬细胞功能缓解急性和慢性同种异体移植物排斥反应的作用机制研究
William N Daccarett-Bojanini,Manuel Sollmann,Kristine M Yarnoff et al.
William N Daccarett-Bojanini et al.
Introduction: We have recently shown that the DNA hypomethylating agent decitabine (DAC) rescues lung allografts from acute rejection. This involves a mechanism that is dependent on host CD4+ FoxP3+ T cells for maximal be...
A study on the distribution of BK and JC polyomavirus in discarded donor kidneys [0.03%]
捐腎器官中BK病毒和JC病毒的分佈研究
Wouter T Moest,Aiko P J de Vries,Reshma A Lalai et al.
Wouter T Moest et al.
Introduction: BK polyomavirus (BKPyV) and JC polyomavirus (JCPyV) are thought to establish persistent, low-grade infections in the kidney. However, their specific intrarenal reservoirs remain unclear. To explore their loc...
Viola A Stögner,Dean M Pucciarelli,Lauren Harkins et al.
Viola A Stögner et al.
Introduction: Donor-recipient compatibility remains a central determinant of transplant success, yet conventional antigen-level human leukocyte antigen (HLA) matching provides limited resolution for predicting alloimmune ...
Comparative evaluation of five tacrolimus assays in transplant recipients: implications for optimizing therapeutic drug monitoring [0.03%]
评估移植受者的五种他克莫司检测方法:优化治疗药物监测的启示
Ivo N SahBandar,Zhen Zhao,Sabrina E Racine-Brzostek et al.
Ivo N SahBandar et al.
Tacrolimus is a widely used immunosuppressive therapy in transplant recipients, but its narrow therapeutic index necessitates accurate monitoring. Tacrolimus levels can be quantified using immunoassays (IAs) and liquid chromatography-tandem...
Thomas E. Starzl, M.D., Ph.D-the Sui Generis Medical Pioneer and Mentor [0.03%]
星一代医学拓荒者与导师托马斯·E·斯塔兹尔博士
John J Fung,Merit Remzi
John J Fung
As the "Father of Modern Transplantation", Dr. Starzl pioneered every aspect of organ transplantation: immunosuppression, organ procurement and preservation, tissue matching, surgical transplant technology, and the operational management of...
Glycocalyx kinetics and injury during liver procurement and transplantation as predictors of early graft dysfunction [0.03%]
肝脏获取与移植过程中糖萼动力学和损伤预测早期移植物功能障碍
Nassiba Beghdadi,Alexis Texier,Marc Antoine Allard et al.
Nassiba Beghdadi et al.
Introduction: Ischemia-reperfusion injury causes endothelial damage, partly through degradation of the glycocalyx. This study aimed to evaluate glycocalyx degradation from graft procurement to reperfusion and assess its p...
Impact of different blood group incompatibilities in kidney transplantation: a 15-year outcomes analysis from a large kidney transplant center [0.03%]
血型不相容对肾移植受者的长期影响分析
Dalia A Obeid,Dieter C Broering,Khalid A AlMeshari et al.
Dalia A Obeid et al.
Background: While ABO-incompatible kidney transplantation (ABOiKT) has demonstrated favorable short-term outcomes, data on its long-term effects remain limited. This study evaluated the short- and long-term clinical outco...