Mechanisms inducing differentiation of adult islet progenitor-like cells into functional islet-like organoids [0.03%]
调控成人类似干细胞定向分化为功能胰岛类器官的机制研究
Carly M Darden,Jayachandra Kuncha,Jeffrey T Kirkland et al.
Carly M Darden et al.
Introduction: Adult pancreatic tissue contains cell populations with latent regenerative potential, but the processes governing their expansion and differentiation into endocrine lineages remain unclear. ...
Cláudia Silva Souza,Niels Olsen Saraiva Camara,Thaís Alves-Silva
Cláudia Silva Souza
Chronic kidney disease (CKD) is recognized as one of the most significant public health issues globally, with approximately 40% of patients progressing to end-stage kidney disease (ESKD). Transplantation remains the most indicated option fo...
Standardized evaluation protocols for deceased and living liver donors: a practical framework for emerging liver transplant programs [0.03%]
尸体和活体肝移植供者的标准化评估方案：新兴肝脏移植项目的实用框架
Pablo Coste Murillo,Rodrigo Álvarez Buitrago,Vanessa López Jara et al.
Pablo Coste Murillo et al.
Background: Liver transplantation (LT) remains the definitive therapy for end-stage liver disease. However, significant variability in infrastructure, policy, and clinical practice continues to influence the implementatio...
100 most-cited publications in vascularized composite allotransplantation [0.03%]
实体器官与组织复合移植排异反应的最具影响力的100篇文章分析（SCI检索）
Pharel Njessi,Carter J Boyd,Palmina Petruzzo et al.
Pharel Njessi et al.
Background: Citation analysis is a useful bibliometric tool to identify impactful publications and trace the evolution of a specialty or a technique. In the past three decades, the research on vascularized composite allot...
The risk of kidney transplant graft loss in sensitized vs. unsensitized patients is modified by prior transplant status [0.03%]
既往移植史可改变供者特异性抗体阳性受者与阴性受者肾脏移植后移植物丢失的风险比
A Nicholson,K Tennankore,A J Vinson
A Nicholson
Background: A prior kidney transplant (KT) has been associated with an increased risk of graft loss following repeat transplantation. This study examined the risk of adverse posttransplant outcomes between patients with a...
24-hour ex vivo perfusion of vascularized composite allografts in a large animal total limb model [0.03%]
大型动物肢体移植血管化复合组织异种异体移植的24小时灌注实验研究
Çağdaş Duru,Alina Stoian,Felor Biniazan et al.
Çağdaş Duru et al.
Background: Static cold storage (SCS) at 4 °C remains the standard for preserving vascularized composite allotransplants (VCA) but limits viability to approximately 6 h. Ex-vivo perfusion offers a promising alternative. ...
Impaired graft survival in kidney transplants from expanded criteria donors with HLA-DR mismatch [0.03%]
供者扩展标准供体肾脏移植受者中存在HLA-DR不匹配时移植物存活率下降
Uwe Scheuermann,Philipp Rhode,Claudia Lehmann et al.
Uwe Scheuermann et al.
Human leukocyte antigen (HLA)-DR mismatches are known to increase the risk of graft rejection following kidney transplantation (KT). Especially in KT using grafts of lower quality from expanded criteria donors (ECD), the immune response pla...
Innovative approaches targeting innate immune cells to promote organ transplant tolerance [0.03%]
针对固有免疫细胞的创新方法促进器官移植耐受性
Chiyoshi Toyama,Angus W Thomson
Chiyoshi Toyama
Achieving long-term allograft survival while minimizing systemic immunosuppression (IS) remains a critical unmet need in transplantation. While adaptive immunity has traditionally been the primary focus of IS therapy, innate immune cells-th...
Machine perfusion for liver transplantation: opportunities and challenges for the next generation of transplant surgeons [0.03%]
机器灌注在肝移植中的应用：下一代移植外科医生的机会与挑战
Cody L Mullens,Kumaran Shanmugarajah,Glenn K Wakam
Cody L Mullens
Machine perfusion is reshaping liver transplantation by turning preservation from passive storage into an active, physiologic intervention. This review synthesizes randomized and real-world evidence on hypothermic oxygenated and normothermi...
Does sex matter? Longitudinal course and predictors of knowledge about immunosuppressant medication in patients after kidney transplantation: a KTx360° substudy [0.03%]
性别会影响移植物肾脏患者的免疫抑制剂药物相关知识的纵向进程和预测因素吗？来自KTx360°亚研究的结果
Mariel Nöhre,Deborah Meier,Julia Talamo et al.
Mariel Nöhre et al.
Background: To ensure long term graft and patient survival after kidney transplantation, the correct intake of the immunosuppressive medication is mandatory. To correctly administer the medication, specific knowledge is r...