Purification and transcriptomic characterization of proliferative cells of Mesocestoides corti selectively affected by irradiation [0.03%]
辐照选择性影响的Mesocestoides corti增殖细胞的纯化及转录组特征分析
Alicia Costábile,María Fernanda Domínguez,Inés Guarnaschelli et al.
Alicia Costábile et al.
Flatworms depend on stem cells for continued tissue growth and renewal during their life cycles, making these cells valuable drug targets. While neoblasts are extensively characterized in the free-living planarian Schmidtea mediterranea, an...
Understanding the Cryptosporidium species and their challenges to animal health and livestock species for informed development of new, specific treatment strategies [0.03%]
理解Cryptosporidium物种及其对动物健康和家畜品种的挑战，以制定新的、特定的治疗策略
Hannah Rideout,Alasdair J C Cook,Anthony D Whetton
Hannah Rideout
Cryptosporidium species are parasitic organisms of vertebrates with a worldwide distribution. They have an important impact globally upon human and animal health, and livestock productivity. The life cycle of these species is complex and di...
Norma Bautista-Lopez,Momar Ndao
Norma Bautista-Lopez
The Polymerase Chain Reaction (PCR) test is a highly sensitive, specific, and rapid diagnostic tool for Chagas disease. Chagas disease is caused by the protozoan flagellate Trypanosoma cruzi and is endemic to the Americas. While conventiona...
Malaria and associated factors among under-five children in Borena pastoral communities, southern Ethiopia [0.03%]
埃塞俄比亚南部博雷纳游牧社区5岁以下儿童疟疾及其相关因素
Alqeer Aliyo,Wako Golicha,Anteneh Fikrie
Alqeer Aliyo
Background: Malaria continues to be an important threat to public health and infects millions of children under 5 years of age each year. Although Ethiopia has set targets for at-risk group interventions to eradicate and ...
Gabriela Eastham,Dane Fausnacht,Matthew H Becker et al.
Gabriela Eastham et al.
Schistosomiasis is a group of both acute and chronic parasitic trematode infections of the genus Schistosoma. Research into schistosomiasis has been minimal, leading to its classification as a neglected tropical disease, yet more than 140 m...
EhVps35, a retromer component, is involved in the recycling of the EhADH and Gal/GalNac virulent proteins of Entamoeba histolytica [0.03%]
EHVPS35（回肠蛋白成员）参与溶组织内阿米巴致病蛋白EhADH和Gal/GalNAc的循环利用
Joselin Díaz-Valdez,Rosario Javier-Reyna,Sarita Montaño et al.
Joselin Díaz-Valdez et al.
The retromer is a highly conserved eukaryotic complex formed by the cargo selective complex (CSC) and the sorting nexin (SNX) dimer subcomplexes. Its function is protein recycling and recovery from the endosomes to conduct the target molecu...
Identification of potent schistosomicidal compounds predicted as type II-kinase inhibitors against Schistosoma mansoni c-Jun N-terminal kinase SMJNK [0.03%]
基于II型激酶抑制剂预测的曼氏血吸虫c-Jun氨基末端激酶SMJNK强效schistosomicidal化合物鉴定
Bernardo P Moreira,Sandra G Gava,Simone Haeberlein et al.
Bernardo P Moreira et al.
Introduction: Schistosomiasis has for many years relied on a single drug, praziquantel (PZQ) for treatment of the disease. Immense efforts have been invested in the discovery of protein kinase (PK) inhibitors; however, gi...
Genetic variation of the Plasmodium falciparum circumsporozoite protein in parasite isolates from Homabay County in Kenya [0.03%]
肯尼亚霍马贝县疟原虫隔孢子体蛋白的基因变异
Michael Maina,Sebastian Musundi,Josiah Kuja et al.
Michael Maina et al.
The Plasmodium falciparum Circumsporozoite Protein (PfCSP) has been used in developing the RTS,S, and R21 malaria vaccines. However, genetic polymorphisms within Pfcsp compromise the effectiveness of the vaccine. Thus, it is essential to co...
Immunomodulatory properties of Leishmania tarentolae extracellular vesicles containing the Spike protein of SARS-CoV-2 [0.03%]
含有SARS-CoV-2刺突蛋白的Leishmania tarentolae细胞外囊泡的免疫调节特性
Ana Catalina Medina,Hamlet Acevedo Ospina,Albert Descoteaux
Ana Catalina Medina
Extracellular vesicles released by the protozoan parasite Leishmania display immunomodulatory properties towards mammalian immune cells. In this study, we have evaluated the potential of extracellular vesicles derived from the non-pathogeni...
From laboratory to clinical practice: an update of the immunological and molecular tools for neurocysticercosis diagnosis [0.03%]
从实验室到临床实践：更新神经囊尾蚴病免疫学和分子诊断工具
Luz M Toribio,Javier A Bustos,Hector H Garcia
Luz M Toribio
Neurocysticercosis (NCC) is caused by the invasion of Taenia solium larvae in the central nervous system (CNS) and stands as the predominant cause of epilepsy and other neurological disorders in many developing nations. NCC diagnosis is cha...