An essential Trypanosoma brucei protein kinase: a functional analysis of regulation and the identification of inhibitors [0.03%]
重要寄生虫蛋白激酶的功能分析及抑制剂的鉴定
Marilyn Parsons,Ben Parsons,Marissa Dean et al.
Marilyn Parsons et al.
Introduction: The protein serine/threonine kinase AEK1 is essential in the pathogenic stage of Trypanosoma brucei, the causative agent of African trypanosomiasis. AEK1 is a member of the AGC protein kinase family, althoug...
Comparison of molecular surveillance methods to assess changes in the population genetics of Plasmodium falciparum in high transmission [0.03%]
比较分子监测方法以评估高传播率地区恶性疟原虫种群遗传学的变化
Anita Ghansah,Kathryn E Tiedje,Dionne C Argyropoulos et al.
Anita Ghansah et al.
A major motivation for developing molecular methods for malaria surveillance is to measure the impact of control interventions on the population genetics of Plasmodium falciparum as a potential marker of progress towards elimination. Here w...
Jan R Mead
Jan R Mead
Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the small intestine and cause diarrheal illness in both immunocompetent and immunodeficient individuals. These infections may be more severe in immun...
Richard J Martin
Richard J Martin
Unravelling var complexity: Relationship between DBLα types and var genes in Plasmodium falciparum [0.03%]
解开var基因的复杂性：疟原虫中DBLα型和var基因之间的关系
Mun Hua Tan,Heejung Shim,Yao-Ban Chan et al.
Mun Hua Tan et al.
The enormous diversity and complexity of var genes that diversify rapidly by recombination has led to the exclusion of assembly of these genes from major genome initiatives (e.g., Pf6). A scalable solution in epidemiological surveillance of...