Role of peroral cholangioscopy and pancreatoscopy in the diagnosis and treatment of biliary and pancreatic disease: past, present, and future [0.03%]
内镜胆道胰管子镜技术在胆胰疾病诊断和治疗中作用的过去、现在与未来
Harishankar Gopakumar,Neil R Sharma
Harishankar Gopakumar
Peroral cholangiopancreatoscopy was described as early as the 1950s. However, the small caliber of these ducts and the technological limitations in developing slender, maneuverable, high-definition scopes posed a challenge. Peroral cholangi...
Preventing acute diverticulitis. any roles for non-absorbable antibiotics? in search of evidence: a systematic review, meta-analysis, and trial sequential analysis [0.03%]
急性憩室炎的预防：非吸收性抗生素的作用吗？寻找证据：系统评价、-meta分析和序贯试验分析
Maurizio Koch,Alberto Enrico Maraolo,Giuseppe Natoli et al.
Maurizio Koch et al.
Background: Hospital admissions for diverticulitis, a complication of diverticular disease, are very much on the increase. Prevention of diverticulitis could cut costs and save lives. ...
Guilherme Grossi Lopes Cançado,Aline Coelho Rocha Candolo,Mateus Jorge Nardelli et al.
Guilherme Grossi Lopes Cançado et al.
Introduction: Cryptogenic chronic hepatitis is a growing cause of liver transplants, affecting 5%-15% of patients with chronic liver diseases. This study aimed to identify underlying causes of cryptogenic liver disease in...
Current and future opportunities for the management of primary biliary cholangitis [0.03%]
当前和未来原发性胆汁性胆管炎的治疗机遇
Sandra Naffouj,Jennifer Wang
Sandra Naffouj
Primary biliary cholangitis (PBC) is a rare immune-mediated chronic cholestatic liver disease that can progress to liver fibrosis and, ultimately, cirrhosis if left untreated. Since the pathogenesis of PBC is not well understood, curative t...
Intensified anti-TNF treatment downregulates the phenotype in ulcerative colitis: a 13-year prospective follow-up study [0.03%]
强化抗TNF治疗可降低溃疡性结肠炎表型：一项为期13年的前瞻性随访研究
Jon Florholmen,Rasmus Goll,Kay-Martin Johnsen
Jon Florholmen
Background: Moderate to severe ulcerative colitis (UC) is generally treated with a step-up algorithm from 5-aminosalicylic acid (5-ASA) to biological agents. There is no general recommendation if or when to de-escalate or...
A rare and severe complication after minimally invasive esophagectomy: First case of a left-sided tension pneumothorax caused by intrathoracic perforation of the herniated transverse colon. Case report and literature review [0.03%]
微创食管切除术后的罕见严重并发症：由横结肠膈疝穿孔所致左侧张力性气胸首例报告及文献回顾
Karim Mostafa,Carmen Wolf,Johannes Austrup et al.
Karim Mostafa et al.
Nowadays, a minimally invasive surgical approach is increasingly being chosen to treat distal esophageal tumors. Here, postoperative hiatal herniation has been identified as a potentially severe complication. In such cases, it is still not ...
Adalimumab biosimilar ABP 501 is equally effective and safe in long-term management of inflammatory bowel diseases patients when used as first biologic treatment or as replace of the ADA originator for a non-medical reason [0.03%]
阿达木单抗生物类似物ABP 501在作为初始治疗药物或由于非医学原因替换原研阿达木单抗时，可有效安全的长期管理炎症性肠病患者
Giammarco Mocci,Arianna Cingolani,Giorgia Orrù et al.
Giammarco Mocci et al.
Objective: Biosimilars represent a new opportunity for inflammatory bowel disease (IBD) treatment and economic sustainability of therapies. This study aimed to evaluate the efficacy and long-term safety of the adalimumab ...
Editorial: Gut microbiota and chemotherapy resistance of colorectal cancer [0.03%]
述评：肠道菌群与结直肠癌化疗耐药性
Yijia Wang,Xuehua Wan,Shaobin Hou
Yijia Wang
Editorial: Exploring the interplay between clinical and non-clinical outcomes for children and adults with inflammatory bowel disease [0.03%]
述评：炎症性肠病患儿及成人临床结局和非临床结局相互作用的影响因素探究
Angharad Vernon-Roberts,Tiffany Taft,Taryn Lores et al.
Angharad Vernon-Roberts et al.
Pallavi Garg,Kaushal Madan
Pallavi Garg
Acute-on-chronic liver failure (ACLF) is a complex health problem with a high short-term mortality. It is a form of end-stage liver disease (ESLD) characterized by acute hepatic insult on the background of an underlying chronic liver diseas...