Triple monoclonal protein-related kidney lesions in a patient with plasma cell dyscrasia: a case report [0.03%]
一例浆细胞异常患者 triple 单克隆蛋白相关性肾损害的病例报告
Arsalan Alvi,Alexander J Gallan,Nattawat Klomjit
Arsalan Alvi
A toxic monoclonal protein typically results in a single kidney pathology due to the specific biophysical characteristics of monoclonal proteins. Multiple monoclonal protein lesions are rarely reported and often portend a poor prognosis. We...
Commentary: Obstructive sleep apnea in the hemodialysis population: are clinicians putting existing scientific evidence into practice? [0.03%]
评论：血液透析人群中的阻塞性睡眠呼吸暂停：临床医生是否将现有的科学证据应用于实践中？
Aleena Jamal,Som P Singh,Fawad Qureshi
Aleena Jamal
Prognostic significance of fibrinogen levels in sepsis-associated acute kidney injury: unveiling a nonlinear relationship and clinical implications [0.03%]
纤维蛋白原水平在脓毒症相关急性肾损伤中的预后价值：揭示非线性关系及其临床意义
Manqin Chen,Xinbin Chen,Huaxiang Ling et al.
Manqin Chen et al.
Background: Fibrinogen plays a pivotal role in the inflammatory cascade and is intricately linked to the pathogenesis of sepsis. Nevertheless, its significance as a prognostic marker for sepsis-associated acute kidney inj...
Increased levels of antibodies to synaptopodin and annexin 1 in patients with primary podocytopathies [0.03%]
原发性足细胞疾病患者中synaptopodin和annexin A1抗体水平升高
Natalia V Chebotareva,Evgeniya A Charionovskaya,Evgenia A Biryukova et al.
Natalia V Chebotareva et al.
Introduction: Circulating anti-podocyte antibodies have been proposed as potential factors contributing to increased permeability in primary podocytopathies, such as Minimal Change Disease (MCD) and Focal Segmental Glomer...
Proteinuria and proximal tubular epithelial cells: correlation between immunofluorescence, histology, and degree of proteinuria [0.03%]
蛋白尿与近端小管上皮细胞：免疫荧光、组织学与蛋白尿程度的相关性研究
Maria Bernadette Cy Chow,Vedat Yildiz,Laura Biederman et al.
Maria Bernadette Cy Chow et al.
Proteins are filtered from the blood through the glomerular filtration barrier. Filtered proteins are reabsorbed by proximal tubular epithelial cells (PTECs), which have been shown to possess the ability to regulate protein reabsorption. Hi...
C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation [0.03%]
补体替代途径失调介导的肾小球疾病-C3肾小球病
Karin Heidenreich,Deepti Goel,P S Priyamvada et al.
Karin Heidenreich et al.
C3 glomerulopathy (C3G) is an ultra-rare complement-mediated kidney disease caused by to the deregulation of the alternative pathway (AP) of proximal complement. Consequently, all effector loops of the complement are active and can lead to ...
Desidustat: a novel PHD inhibitor for the treatment of CKD-induced anemia [0.03%]
Desidustat：一种用于治疗慢性肾脏病相关性贫血的新型脯氨酰羟化酶抑制剂
Amit Joharapurkar,Vrajesh Pandya,Harilal Patel et al.
Amit Joharapurkar et al.
Desidustat is a small molecule inhibitor of hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) discovered and developed by Zydus Lifesciences for the treatment of anemia associated with chronic kidney disease (CKD). This review summarizes...
The clinical course of SARS-CoV-2 infection in patients with glomerular diseases and evaluation of the subsequent risk of relapse [0.03%]
肾小球病患者感染SARS-CoV-2的临床过程及评估病情复发的风险
Sophia Lionaki,Evangelia Dounousi,Smaragdi Marinaki et al.
Sophia Lionaki et al.
Introduction: This study aimed to describe the clinical course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with glomerular diseases (GDs) and its impact on the probability of rela...
Inside CKD: a microsimulation modelling study projects the clinical and economic burden of chronic kidney disease in Hungary [0.03%]
CKD预估仿真研究：评估慢性肾脏病在匈牙利的临床和经济负担
Lilla Szabó,Luca Adél Halmai,Erzsébet Ladányi et al.
Lilla Szabó et al.
Objectives: The Inside CKD programme implemented a microsimulation modelling approach to project the clinical and economic burden of chronic kidney disease (CKD) between 2024 and 2027 in Hungary. ...
Quantifying measurement uncertainty in renal transplant biopsy assessment [0.03%]
肾移植活检评估中的测量不确定性的量化分析
Xavier Loizeau,Marina Romanchikova,Spencer A Thomas et al.
Xavier Loizeau et al.
Introduction: Renal transplant biopsies provide insights into graft health and support decision making. The current evidence on links between biopsy scores and transplant outcomes suggests there may be numerous factors af...