Case report: Unveiling a less severe congenital nephrotic syndrome in a Rapa Nui patient with a NPHS1 Maori founder variant [0.03%]
病例报告：在一名携带波利尼西亚人NPHS1创始人突变的拉帕努伊综合征患者中揭示一种较轻的先天性肾病综合征
Paola Krall,Angélica Rojo,Anita Plaza et al.
Paola Krall et al.
Background: Congenital nephrotic syndrome (CNS) is a severe kidney disorder characterized by edema, massive proteinuria, and hypoalbuminemia that manifests in utero or within three months after birth. CNS affects 1-3 per ...
Arushi Nautiyal,Soumita Bagchi,Shyam Bihari Bansal
Arushi Nautiyal
Kidney transplantation provides the best form of kidney replacement therapy with improvement in quality of life and longevity. However, disparity exists in its availability, utilisation and outcomes, not only due to donor availability or fi...
Marco Aurelio Salvino,Alberto Mussetti,Marta Peña et al.
Marco Aurelio Salvino et al.
Cell therapy, specifically the revolutionary chimeric antigen receptor (CAR) T-cell therapy, has transformed the landscape of oncology, making substantial strides in practical treatment approaches. Today, established guidelines for diseases...
SGLT2 inhibitors in diabetic and non-diabetic kidney transplant recipients: current knowledge and expectations [0.03%]
钠-葡萄糖协同转运蛋白2抑制剂在糖尿病和非糖尿病肾脏移植受者中的应用：目前的研究成果与展望
Erietta Polychronopoulou,Fanny Bourdon,Daniel Teta
Erietta Polychronopoulou
The beneficial effect of sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been shown recently in numerous randomized controlled trials (RCT) and systematic reviews. According to KDIGO guidelines, SGLT2i currently represent a first ch...
Mario Alamilla-Sanchez,Juan Daniel Diaz Garcia,Valeria Yanez Salguero et al.
Mario Alamilla-Sanchez et al.
Acquired tubulopathies are frequently underdiagnosed. They can be characterized by the renal loss of specific electrolytes or organic solutes, suggesting the location of dysfunction. These tubulopathies phenotypically can resemble Bartter o...
Bioinformatics-driven identification of prognostic biomarkers in kidney renal clear cell carcinoma [0.03%]
基于生物信息学的肾透明细胞癌预后生物标志物识别研究
Varinder Madhav Verma,Sanjeev Puri,Veena Puri
Varinder Madhav Verma
Renal cell carcinoma (RCC), particularly the clear cell subtype (ccRCC), poses a significant global health concern due to its increasing prevalence and resistance to conventional therapies. Early detection of ccRCC remains challenging, resu...
NELL1 membranous nephropathy: clinical associations provide mechanistic clues [0.03%]
NELL1膜性肾病：临床相关性提供机制线索
Nicole K Andeen,Vanderlene L Kung,Rupali S Avasare
Nicole K Andeen
Neural epidermal growth factor-like 1 (NELL1) membranous nephropathy (MN) is notable for its segmental deposit distribution, IgG1 dominant deposits, and comparatively high rate of spontaneous remission. It has been associated with a variety...
Gender disparity in maintenance hemodialysis units in South India: a cross-sectional observational study [0.03%]
印度南部维持性血液透析中心的性别差异：一项横断面观察研究
Mythri Shankar,Gouri Satheesh,Kishan A et al.
Mythri Shankar et al.
Background: Diseases manifest differently according to gender in many medical specialties. However, sex differences in kidney diseases have not been well explored worldwide, especially in India. These differences could al...
The role of online hemodiafiltration with endogenous reinfusion in the treatment of systemic lupus erythematosus activity resistant to conventional therapy [0.03%]
在线性透析滤过联合内源性血浆再循环治疗难治性系统性红斑狼疮中的作用
Mohammed A Elghiriani,Salah S Naga,Ibtessam A Hameed et al.
Mohammed A Elghiriani et al.
Introduction: Lupus is a diverse autoimmune disease with autoantibody formation. Lupus nephritis carries a grave prognosis. Complement involvement, namely, C1q deficiency, is linked to activity and renal involvement and c...
Alterations in urinary ceramides, sphingoid bases, and their phosphates among patients with kidney disease [0.03%]
肾病患者尿液中丝氨醇衍生物的变化规律研究
Yoshifumi Morita,Eri Sakai,Hideaki Isago et al.
Yoshifumi Morita et al.
Background: To avoid an invasive renal biopsy, noninvasive laboratory testing for the differential diagnosis of kidney diseases is a desirable goal. As sphingolipids are demonstrated to be involved in the pathogenesis of ...