Endogenous vasopressin and vasopressin receptor 2 in bladder as anti-diuretic / anti-spasmodic targets for the treatment of multifactorial nocturia [0.03%]
内源性血管加压素和膀胱血管加压素受体2作为治疗多因素夜尿的抗利尿/抗痉挛靶点
Irina Zabbarova,Pradeep Tyagi,Youko Ikeda et al.
Irina Zabbarova et al.
Introduction: Nocturia, the urge to wake from sleep to void, is targeted sub-optimally by existing drugs that modulate circadian dysregulation of urine production in kidney without alleviating detrusor overactivity, a key...
Sensation kinetics identifies novel bladder sensation-capacity curve shapes during urodynamics in patients with urinary urgency [0.03%]
感觉动力学识别了间质性膀胱炎/膀胱疼痛综合征患者在尿动力学期间新的膀胱感觉-容量曲线形状
John E Speich,Annapoorani Narayanan,Mrudula Bandaru et al.
John E Speich et al.
Objective: Overactive bladder (OAB) is characterized by urinary urgency. To better characterize the relationship between bladder sensation and urgency, a tablet-based "Sensation Meter" was developed to enable construction...
Development, usability, and randomized pilot feasibility study of a mobile application prototype supporting self-management of accidental bowel leakage [0.03%]
移动应用支持失禁患者自我管理的开发、实用性和随即试点可行性研究
Donna Z Bliss,Olga V Gurvich,Joseph A Konstan et al.
Donna Z Bliss et al.
Aims: Patients need support in managing conservative interventions for fecal incontinence (FI). To address this need, a three-phased study aimed to develop and test the usability of a mobile application prototype (App-p) ...
Patients' experiences with self-management of conservative interventions for fecal incontinence [0.03%]
粪失禁患者保守治疗自我管理体验的研究
Donna Z Bliss,Marshall K Muehlbauer,Dominique Jamison et al.
Donna Z Bliss et al.
Aims: To describe patients' experience self-managing conservative interventions for fecal incontinence (FI) during usual FI care. Methods: ...
PROBING THE INTERPLAY OF PERFUSION AND PERMEABILITY IN BLADDER INFLAMMATION [0.03%]
探究膀胱炎中灌注与通透性的相互作用
P Tyagi,C Moon,Jun C Kang et al.
P Tyagi et al.
Mindfulness and Transcranial Direct Current Stimulation (tDCS) to Attenuate Situational Urgency Urinary Incontinence (UUI): A randomized pilot study [0.03%]
正念和经颅直流电刺激(tDCS)减轻急迫性尿失禁(UUI):一项随机试点研究
Cynthia A Conklin,Brian Coffman,Carol M Greco et al.
Cynthia A Conklin et al.
Introduction: Situational urgency urinary incontinence (UUI), triggered by situations such as approaching the front door and running water, accounts for up to half of all UUI episodes in women. We proposed a behavioral th...
A deeper exploration of functional connectivity of brain regions regulating bladder function in healthy adults [0.03%]
健康成年人调节膀胱功能脑区的功能连接的进一步探索
Arda Bayer,Kris Hoffman,Betsy Salazar et al.
Arda Bayer et al.
Functional magnetic resonance imaging (fMRI) has been the primary tool in human research for studying and advancing our understanding of neural control of the bladder. Although the current working model identifies several brain regions invo...
Unraveling the complexity of bladder-centric chronic pain by intravesical contrast enhanced MRI [0.03%]
基于膀胱的慢性疼痛的复杂性通过膀胱内对比增强MRI进行解析
Pradeep Tyagi,Jodi Maranchie,Rajiv Dhir et al.
Pradeep Tyagi et al.
Bladder pain, a common symptom associated with various urological conditions, poses a diagnostic challenge as existing imaging modalities fail to pinpoint the bladder as the definitive source of pain. While bladder pain is often linked to l...
Bladder capacity as a benchmark for patient stratification in interstitial cystitis/bladder pain syndrome [0.03%]
间质性膀胱炎/膀胱疼痛综合征患者分层中的标杆指标：膀胱容量
Maxwell Sandberg,Dylan T Wolff,Wyatt Whitman et al.
Maxwell Sandberg et al.
Objectives: In a previous study we reported that molecular profiling of bladder mucosal tissue from a modest number of IC/BPS patients resulted in a clear separation based on anesthetic bladder capacity (BC), with 400 cc ...
The many facets of perceived bladder health in women: Absence of symptoms and presence of healthy behaviors across the life course [0.03%]
女性膀胱健康的多面性：一生中健康行为的存在与否和症状的有无
Lisa Kane Low,Beverly Rosa Williams,Diane K Newman et al.
Lisa Kane Low et al.
Purpose: Qualitative studies exploring bladder health are rare compared to research focusing on lower urinary tract symptoms (LUTS). Our aim was to explore adolescent and adult women's perceptions about what constitutes a...