Plasma Ceramide C24:0/C16:0 Relates to Outcomes in Patients With Heart Failure With Preserved Ejection Fraction [0.03%]
血清 ceramide C24:0/C16:0 与射血分数保留心力衰竭患者预后相关性研究
Linda R Peterson,Stefan Gross,Marcus Dörr et al.
Linda R Peterson et al.
Background: Ceramides are complex sphingolipids with pleiotropic effects. The ratio of specific ceramides (plasma C24:0/C16:0) is inversely related to incident heart failure (HF) and all-cause death in large, community-ba...
Unfavorable Social Determinants of Health and Obesity: A Double Jeopardy for Premature Mortality [0.03%]
不利的社会决定因素与肥胖对过早死亡的叠加影响
Jerrin Philip,Kobina Hagan,Izza Shahid et al.
Jerrin Philip et al.
Background: Obesity is a well-established risk factor for cardiovascular disease and mortality, but its interplay with social determinants of health (SDoH) remains inadequately studied. Socioeconomic disadvantage can exac...
Joint Consideration of LDL-C and Polygenic Risk for Coronary Heart Disease Risk Assessment [0.03%]
冠心病风险评估中联合考虑LDL-C和多基因风险评分的影响
Carlos Iribarren,Meng Lu,Roberto Elosua et al.
Carlos Iribarren et al.
Plant-Based Diet Quality, Healthy Lifestyle, and Dementia Risk in Older Adults With Cardiometabolic Diseases [0.03%]
基于植物的饮食质量、健康生活方式与心血管代谢疾病老年人的认知衰退风险的关系研究
Michelle M Dunk,Abigail Dove,Jiao Wang et al.
Michelle M Dunk et al.
Background: Cardiometabolic diseases (CMDs; heart disease, stroke, and type 2 diabetes) are associated with dementia risk, but whether a healthy plant-based diet and other lifestyle behaviors can mitigate this risk is unc...
Cardiorespiratory Fitness, Multimorbidity Risk, and 15-Year Trajectories in Chronic Disease Accumulation: A Prospective Longitudinal Study [0.03%]
有氧运动能力、多发病风险和慢性疾病累积的15年轨迹：一项前瞻性纵向研究
Liyao Xu,Shuqi Wang,Maiwulamujiang Maimaitiyiming et al.
Liyao Xu et al.
Background: Cardiorespiratory fitness (CRF) has been linked to lower risk of individual chronic diseases, but little is known about the CRF in relation to multimorbidity. ...
Long-Term Survival Advantage of Total Arterial Revascularization in Elderly Patients Following Coronary Artery Bypass Grafting [0.03%]
老年患者冠状动脉旁路移植术后全动脉化优势的长期存活分析
Justin Ren,Christopher M Reid,Julian A Smith et al.
Justin Ren et al.
Background: Despite the evidence of clinical benefit, total arterial revascularization (TAR) remains underutilized in elderly patients undergoing coronary artery bypass grafting due to concerns about perceived surgical co...
Carl J Lavie,Charles Faselis,Peter Kokkinos
Carl J Lavie
Developing a Multilevel Polypill Implementation Bundle for Patients With Heart Failure With Reduced Ejection Fraction [0.03%]
开发用于射血分数降低的心力衰竭患者的多层次多药丸实施组合包
Justin C Chen,Colette DeJong,Mansi Agarwal et al.
Justin C Chen et al.
Background: A polypill that contains multiple guideline-directed medical therapies for heart failure with reduced ejection fraction (HFrEF) has been proposed to improve HFrEF outcomes. The factors affecting implementation...
A Fixed-Dose Solution for a Complex Problem: Can Polypills and Implementation Science Improve GDMT Uptake in HFrEF? [0.03%]
固定剂量方案解决复杂问题：合并疗法和实施科学能否提高HFrEF患者对GDMT的接受度？
Quan M Bui,Max Jason
Quan M Bui
Artificial Intelligence Methods Applied to Electronic Health Record Data for Health Equity in Clinical Trials [0.03%]
电子健康档案数据在临床试验中的健康公平性研究中的人工智能方法应用
Jonathan Breeze,Jack Wu,Josie Carmichael et al.
Jonathan Breeze et al.