Layer-by-layer coated calcium carbonate nanoparticles for targeting breast cancer cells [0.03%]
逐层包覆的碳酸钙纳米颗粒用于靶向乳腺癌细胞研究
Filipa R Bastos,Diana Soares da Costa,Rui L Reis et al.
Filipa R Bastos et al.
Breast cancer is resistant to conventional treatments due to the specific tumour microenvironment, the associated acidic pH and the overexpression of receptors that enhance cells tumorigenicity. Herein, we optimized the synthesis of acidic ...
The shape of our gut: Dissecting its impact on drug absorption in a 3D bioprinted intestinal model [0.03%]
人体肠道的形状：在三维生物打印肠道模型中剖析其对药物吸收的影响
Maria Helena Macedo,Núria Torras,María García-Díaz et al.
Maria Helena Macedo et al.
The small intestine is a complex organ with a characteristic architecture and a major site for drug and nutrient absorption. The three-dimensional (3D) topography organized in finger-like protrusions called villi increases surface area rema...
In vitro evaluation of immune responses to bacterial hydrogels for the development of living therapeutic materials [0.03%]
体外评估细菌水凝胶诱发的免疫反应以开发活性治疗材料
Archana K Yanamandra,Shardul Bhusari,Aránzazu Del Campo et al.
Archana K Yanamandra et al.
In living therapeutic materials (LTMs), organisms genetically programmed to produce and deliver drugs are encapsulated in porous matrices acting as physical barriers between the therapeutic organisms and the host cells. LTMs consisting of e...
Recent progress of targeted nanocarriers in diagnostic, therapeutic, and theranostic applications in colorectal cancer [0.03%]
用于结直肠癌诊断、治疗和诊疗一体化应用的靶向纳米载体研究进展
Hira Choudhury,Manisha Pandey,Vilashini Saravanan et al.
Hira Choudhury et al.
Cancer at the lower end of the digestive tract, colorectal cancer (CRC), starts with asymptomatic polyps, which can be diagnosed as cancer at a later stage. It is the fourth leading cause of malignancy-associated mortality worldwide. Despit...
Advanced in vitro hemocompatibility assessment of biomaterials using a new flow incubation system [0.03%]
新型流动孵育系统的建立及血液相容性评价应用研究进展
Claudia Sperling,Manfred F Maitz,Vincent Körber et al.
Claudia Sperling et al.
Physiologically relevant in vitro hemocompatibility assessment of biomaterials remains challenging. We present a new setup that enables standardized whole blood incubation of biomedical materials under flow. A blood volume of 2 mL is recirc...
Towards nanostructured red-ox active bio-interfaces: Bioinspired antibacterial hybrid melanin-CeO2 nanoparticles for radical homeostasis [0.03%]
朝向纳米结构的红/紫杀菌活性生物界面：用于自由基稳态的仿生抗菌混合黑色素-CeO2纳米粒子
Giulio Pota,Brigida Silvestri,Giuseppe Vitiello et al.
Giulio Pota et al.
Redox-active nano-biointerfaces are gaining weight in the field of regenerative medicine since they can act as enzymes in regulating physiological processes and enabling cell homeostasis, as well as the defense against pathogen aggression. ...
Glioblastoma-targeted, local and sustained drug delivery system based on an unconventional lipid nanocapsule hydrogel [0.03%]
一种基于非常规脂质纳米胶囊水凝胶的胶质母细胞瘤靶向、局部和持续药物递送系统
Claire Gazaille,Elia Bozzato,Neda Madadian-Bozorg et al.
Claire Gazaille et al.
The objective of this work was to develop an implantable therapeutic hydrogel that will ensure continuity in treatment between surgery and radiochemotherapy for patients with glioblastoma (GBM). A hydrogel of self-associated gemcitabine-loa...
Combining microfluidics and coaxial 3D-bioprinting for the manufacturing of diabetic wound healing dressings [0.03%]
结合微流体和同铀3D生物打印技术制造糖尿病伤口愈合敷料
Costanza Fratini,Edward Weaver,Sofia Moroni et al.
Costanza Fratini et al.
Diabetic foot ulcers (DFUs) are a crucial complication of diabetes, as in a diabetic wound, each step of the physiological healing process is affected. This entails a more easily infectable wound, and delayed tissue regeneration due to the ...
Natural nanogels crosslinked with S-benzyl-L-cysteine exhibit potent antibacterial activity [0.03%]
S-苄基-l半胱氨酸交联的天然纳米凝胶具有强大的抗菌活性
Fang-Yu Chung,Cheng-Rung Huang,Chang-Shi Chen et al.
Fang-Yu Chung et al.
Biofilm-forming bacteria E. coli and P. aeruginosa have both exhibited resistance against multiple antibiotics in clinical settings. To find a solution, researchers have turned to antibacterial structurally modified from natural materials t...
Polymeric graphene oxide nanoparticles loaded with doxorubicin for combined photothermal and chemotherapy in triple negative breast cancer [0.03%]
聚多西他赛的石墨烯氧化物聚合纳米粒用于三阴性乳腺癌光热与化疗联合治疗
Asif Mohd Itoo,Milan Paul,Balaram Ghosh et al.
Asif Mohd Itoo et al.
Combining photothermal and chemotherapy is an emerging strategy for tumor irradiation in a minimally invasive manner, utilizing photothermal transduction agents and anticancer drugs. The present work developed a 2D carbon nanomaterial graph...