Microfluidic coaxial 3D bioprinting of cell-laden microfibers and microtubes for salivary gland tissue engineering [0.03%]
基于微流体同轴技术的含细胞微纤维和微管三维生物打印及应用 saliva-gland组织工程
Yu Yin,Ephraim J Vázquez-Rosado,Danielle Wu et al.
Yu Yin et al.
Replacement therapy for the salivary gland (SG) remains an unmet clinical need. Xerostomia ("dry mouth") due to hyposalivation can result from injury or disease to the SG, such as salivary acinar death caused by radiation therapy (RT) for h...
Current application and modification strategy of marine polysaccharides in tissue regeneration: A review [0.03%]
海洋多糖在组织再生中的 current application 和 modification 策略：综述文章
Zhaokun Wang,Zhiwen Xu,Xuan Yang et al.
Zhaokun Wang et al.
Marine polysaccharides (MPs) are exceptional bioactive materials that possess unique biochemical mechanisms and pharmacological stability, making them ideal for various tissue engineering applications. Certain MPs, including agarose, algina...
Bioinspired mineralization of engineered living materials to promote osteogenic differentiation [0.03%]
仿生矿化工程活性材料以促进骨发生分化
Belén Parra-Torrejón,Vineetha Jayawarna,Aleixandre Rodrigo-Navarro et al.
Belén Parra-Torrejón et al.
In this work, Engineered Living Materials (ELMs), based on the combination of genetically-modified bacteria and mineral-reinforced organic matrices, and endowed with self-healing or regenerative properties and adaptation to specific biologi...
Anti HER-2 aptamer functionalized gold nanoparticles of dasatinib for targeted chemo-radiotherapy in breast cancer cells [0.03%]
一种针对乳腺癌细胞的靶向化疗放疗的功能化抗HER-2适配体的达沙替尼金纳米粒子
Mahdis Khorshid,Jaleh Varshosaz,Mahboubeh Rostami et al.
Mahdis Khorshid et al.
In the present study, gold nanoparticles functionalized with anti HER-2 aptamer were designed for effective targeted delivery of dasatinib (DSB) to breast cancer cells. Anti HER-2 aptamer attached to porous or plain gold nanoparticles were ...
The ad hoc chemical design of random PBS-based copolymers influences the activation of cardiac differentiation while altering the HYPPO pathway target genes in hiPSCs [0.03%]
基于PBS的随机共聚物的定制合成可影响诱导多能干细胞（hiPSC）中HYPPO通路靶基因，进而影响心脏分化激活
Giulia Guidotti,Robin Duelen,Nora Bloise et al.
Giulia Guidotti et al.
Cardiac tissue engineering is a cutting-edge technology aiming to replace irreversibly damaged cardiac tissue and restore contractile functionality. However, cardiac tissue engineering porous and perfusable scaffolds to enable oxygen supply...
Sustained growth factor delivery from bioactive PNIPAM-grafted-chitosan/heparin multilayers as a tool to promote growth and migration of cells [0.03%]
生物活性PNIPAM接枝壳聚糖/肝素多层膜持续递送生长因子促进细胞增殖和迁移
Yi-Tung Lu,Pei-Tzu Hung,Kui Zeng et al.
Yi-Tung Lu et al.
Delivery of growth factors (GFs) is challenging for regulation of cell proliferation and differentiation due to their rapid inactivation under physiological conditions. Here, a bioactive polyelectrolyte multilayer (PEM) is engineered by the...
Electromechanical and biological evaluations of 0.94Bi0.5Na0.5TiO3-0.06BaTiO3 as a lead-free piezoceramic for implantable bioelectronics [0.03%]
0.94Bi0.5Na0.5TiO3-0.06BaTiO3无铅压电陶瓷在植入式生物电子产品中的机电和生物学评价
Thomas A G Hall,Konstantinos Theodoridis,Stylianos Kechagias et al.
Thomas A G Hall et al.
Smart implantable electronic medical devices are being developed to deliver healthcare that is more connected, personalised, and precise. Many of these implantables rely on piezoceramics for sensing, communication, energy autonomy, and biol...
A new composite fabricated from hydroxyapatite, gelatin-MgO microparticles, and compatibilized poly(butylene succinate) with osteogenic functionality [0.03%]
一种具有成骨功能的羟基磷灰石、明胶-MgO微粒和相容改性的聚丁二酸丁二醇酯复合材料
Dung-Yi Wu,Shan-Shue Wang,Chin-San Wu
Dung-Yi Wu
In this study, thermally processed recycled fish teeth (FT) and fish scales, magnesium oxide (MgO), and biobased polyesters were fabricated into new bioactive and environmentally friendly composites. The magnesium oxide was encapsulated int...
Electrospun fiber-based micro- and nano-system for delivery of high concentrated quercetin to cancer cells [0.03%]
基于静电纺丝的微纳米系统用于高浓度芦丁输送以作用于癌细胞的研究
Andrzej Hudecki,Iwona Rzeszutek,Anna Lewińska et al.
Andrzej Hudecki et al.
The anticancer potential of quercetin (Q), a plant-derived flavonoid, and underlining molecular mechanisms are widely documented in cellular models in vitro. However, biomedical applications of Q are limited due to its low bioavailability a...
Andreas P Kourouklis,Julius Kaemmel,Xi Wu et al.
Andreas P Kourouklis et al.
Alternative engineering approaches have led the design of implants with controlled physical features to minimize adverse effects in biological tissues. Similar efforts have focused on optimizing the design features of percutaneous VAD drive...