Sialic acid-decorated liposomes enhance the anti-cancer efficacy of docetaxel in tumor-associated macrophages [0.03%]
唾液酸修饰脂质体通过调节肿瘤相关巨噬细胞的极化增强多西他赛抗肿瘤功效
Nhan Phan Tran,Phuong Tran,So-Yeol Yoo et al.
Nhan Phan Tran et al.
Tumor-associated macrophages (TAMs) in the tumor microenvironment potentially enhance tumor growth and invasion through various mechanisms and are thus an essential factor in tumor immunity. The highly expressed siglec-1 receptors on the su...
Electro-conductive chitosan/graphene bio-nanocomposite scaffold for tissue engineering of the central nervous system [0.03%]
用于中枢神经系统组织工程的导电壳聚糖/石墨烯生物纳米复合支架
Souvik Ghosh,Megha Dhiman,Sumeet Gupta et al.
Souvik Ghosh et al.
Degenerative central nervous system (CNS) disorders and traumatic brain injuries are common nowadays. These may induce the loss of neuronal cells and delicate connections essential for optimal CNS function. The CNS tissue has restricted reg...
Antibacterial and bioactive multilayer electrospun wound dressings based on hyaluronic acid and lactose-modified chitosan [0.03%]
基于透明质酸和乳糖修饰壳聚糖的抗菌生物活性多层电纺伤口敷料
Martina Gruppuso,Gianluca Turco,Eleonora Marsich et al.
Martina Gruppuso et al.
Antibacterial multilayer electrospun matrices based on hyaluronic acid (HA) and a lactose-modified chitosan (CTL) were synthetized (i) by combining electrospun polycaprolactone (PCL) and polysaccharidic matrices in a bilayer device and (ii)...
Mesh and layered electrospun fiber architectures as vehicles for Lactobacillus acidophilus and Lactobacillus crispatus intended for vaginal delivery [0.03%]
用作阴道递送的兼具网状和分层结构的静电纺丝纤维负载乳酸菌（Lactobacillus acidophilus 和 Lactobacillus crispatus）的载体体系结构
Farnaz Minooei,Abhinav R Kanukunta,Mohamed Y Mahmoud et al.
Farnaz Minooei et al.
Bacterial vaginosis (BV) is a recurrent condition that affects millions of women worldwide. The use of probiotics is a promising alternative or an adjunct to traditional antibiotics for BV prevention and treatment. However, current administ...
Cobalt-doped hollow polydopamine for oxygen generation and GSH consumption enhanced chemo-PTT combined cancer therapy [0.03%]
用于癌症综合治疗的增强型化疗和光热疗的空心聚多巴胺钴掺杂催化剂生成氧气并消耗GSH
Shilong Wu,Qin Zhang,Qiyao Zhao et al.
Shilong Wu et al.
Nanotechnology has revolutionized the field of therapeutics by introducing a plethora of nanomaterials capable of enhancing traditional drug efficacy or paving the way for innovative treatment methods. Within this domain, we propose a novel...
Clofazimine nanoclusters show high efficacy in experimental TB with amelioration in paradoxical lung inflammation [0.03%]
克洛法齐明纳米颗粒在实验性结核病中显示高效，并可改善矛盾性肺部炎症
Krishna Jadhav,Agrim Jhilta,Raghuraj Singh et al.
Krishna Jadhav et al.
The rise of tuberculosis (TB) superbugs has impeded efforts to control this infectious ailment, and new treatment options are few. Paradoxical Inflammation (PI) is another major problem associated with current anti-TB therapy, which can com...
Apatite-coated outer layer eggshell membrane: A novel osteoinductive biohybrid composite for guided bone/tissue regeneration [0.03%]
新型生物杂化复合材料：apatite-coated外层蛋壳膜引导骨组织再生材料
Adriana Torres-Mansilla,Pedro Álvarez-Lloret,Ana Voltes-Martínez et al.
Adriana Torres-Mansilla et al.
Hybrid biomimetic materials aim to replicate the organic-inorganic constructs of mineralized tissues. During eggshell formation, the outer surface of the eggshell membrane (ESM) promotes calcium carbonate nucleation, while the inner one pre...
Multifunctional modifications of polyetheretherketone implants for bone repair: A comprehensive review [0.03%]
用于骨修复的聚醚醚酮植入物的多功能改性：全面综述
Wenzhuo Zheng,Dongxu Wu,Yaowen Zhang et al.
Wenzhuo Zheng et al.
Polyetheretherketone (PEEK) has emerged as a highly promising orthopedic implantation material due to its elastic modulus which is comparable to that of natural bone. This polymer exhibits impressive properties for bone implantation such as...
CD44-targeted nanoparticles for co-delivery of docetaxel and an Akt inhibitor against colorectal cancer [0.03%]
针对结直肠癌协同递送多西他赛和Akt抑制剂的CD44靶向型纳米颗粒疗法
Juan Gonzalez-Valdivieso,Reinaldo Vallejo,Soraya Rodriguez-Rojo et al.
Juan Gonzalez-Valdivieso et al.
New strategies to develop drug-loaded nanocarriers with improved therapeutic efficacy are needed for cancer treatment. Herein we report a novel drug-delivery nanosystem comprising encapsulation of the chemotherapeutic drug docetaxel (DTX) a...
Arginine-carboxylated pullulan, a potential antibacterial material for food packaging [0.03%]
一种潜在的食物包装抗菌材料：瓜尔胶-柠檬酸半酯改性普鲁兰糖复合体系
Lei Zhang,Jianrong Wu,Ziyun Shen et al.
Lei Zhang et al.
Pullulan possesses excellent film-forming properties and oxygen isolation capabilities. However, it exhibits limited antibacterial properties and poor water resistance, thereby hindering its application in the field of food preservation. In...