Chitosan/polydopamine/octacalcium phosphate composite microcarrier simulates natural bone components to induce osteogenic differentiation of stem cells [0.03%]
基于聚多巴胺的壳聚糖/八钙磷酸微载体通过模拟天然骨成分诱导干细胞成骨分化
Guodong Liu,Mengjiao Ma,Huiyi Yang et al.
Guodong Liu et al.
Natural polymers and minerals can be combined to simulate natural bone for repairing bone defects. However, bone defects are often irregular and pose challenges for their repair. To overcome these challenges, we prepared Chitosan/Polydopami...
Ryota Watanabe,Aira Matsugaki,Ozkan Gokcekaya et al.
Ryota Watanabe et al.
Postoperative bacterial infection is a serious complication of orthopedic surgery. Not only infections that develop in the first few weeks after surgery but also late infections that develop years after surgery are serious problems. However...
Subcutaneous angiogenesis induced by transdermal delivery of gel-in-oil nanogel dispersion [0.03%]
通过经皮给药诱导凝胶-油纳米凝胶分散液引起的皮下血管生成
Yi Zhang,Jannatul Fardous,Yuuta Inoue et al.
Yi Zhang et al.
Subcutaneous transplantation aims to enhance the growth and functionality of transplanted cells for therapeutic outcomes in tissue engineering. However, the limited subcutaneous vascular network poses a challenge. Conventional methods invol...
Fabrication of a micro/nanocomposite structure on the surface of high oxygen concentration titanium to promote bone formation [0.03%]
在高氧浓度下制备钛表面微纳米复合结构以促进骨形成
Huiwen Luo,Xiaoou Diao,Fei Qian et al.
Huiwen Luo et al.
This study investigated the properties of the micro/nano composite structure on the surface of high oxygen concentration titanium (HOC-Ti) after anodic oxidation modification (HOC-NT) and evaluated its biocompatibility as a dental implant m...
Amorphous solid dispersion augments the bioavailability of phloretin and its therapeutic efficacy via targeting mTOR/SREBP-1c axis in NAFLD mice [0.03%]
无定形固体分散体通过靶向mTOR/SREBP-1c轴增强白杨茋在治疗NASH小鼠中的生物利用度和疗效
Jyoti Chhimwal,Rakesh Kumar Dhritlahre,Prince Anand et al.
Jyoti Chhimwal et al.
The escalating incidences of non-alcoholic fatty liver disease (NAFLD) and associated metabolic disorders are global health concerns. Phloretin (Ph) is a natural phenolic compound, that exhibits a wide array of pharmacological actions inclu...
Edible coatings and films for shelf-life extension of fruit and vegetables [0.03%]
用于果蔬保鲜的可食性涂膜及包装薄膜技术研究进展
Shristy Chettri,Neha Sharma,Ashish M Mohite
Shristy Chettri
The execution of the edible coatings and films for food preservation; vegetables, fruits, meat, and dry fruits has been ladened in history. The study of literature portrays enough pieces of evidence dating back from centuries of coatings or...
Fabrication of a photo-crosslinkable fluoropolymer-passivated flexible neural probe and acute recording and stimulation performances in vivo [0.03%]
一种可用于体内急性记录和刺激的光交联含氟聚合物隔离柔性神经探针的制备方法及其性能研究
Yong Hee Kim,Ho Koo,Min Sun Kim et al.
Yong Hee Kim et al.
Herein, we fabricated fluorine-containing, polymer-based, flexible neural probes with fluorinated ethylene propylene (FEP) films as the substrates and photo-crosslinkable fluoropolymers as the passivation material. For fabrication, metal-fr...
Garlic extract enhances bioceramic bone scaffolds through upregulating ALP & BGLAP expression in hMSC-monocyte co-culture [0.03%]
大蒜提取物通过促进人骨髓间充质干细胞-单核细胞共培养中碱性磷酸酶和骨钙素的表达来增强生物陶瓷骨支架
Susmita Bose,Samuel F Robertson,Ashley A Vu
Susmita Bose
Bone homeostasis is predicated by osteoblast and osteoclast cell cycles where gene expressions are responsible for their differentiation from human mesenchymal stem cells (hMSC) and monocytes, respectively. The pro-osteogenic potential of a...
Confined synthesis of ternary FeCoMn single-atom nanozyme in N-doped hollow mesoporous carbon nanospheres for synergistic chemotherapy and chemodynamic cancer therapy [0.03%]
限域合成N掺杂中空介孔碳纳米球负载FeCoMn单原子纳米酶用于协同化疗和化学动力学癌症治疗
Yan-Wen Mao,Xu Zhang,Heng-Bo Li et al.
Yan-Wen Mao et al.
Recently, nanozymes show increasing biological applications and promising possibilities for therapeutic intervention, while their mediated therapeutic outcomes are severely compromised due to their insufficient catalytic activity and specif...
Multifunctional bioactive glasses with spontaneous degradation for simultaneous osteosarcoma therapy and bone regeneration [0.03%]
用于同时治疗骨肉瘤和骨再生的可自发降解多功能生物活性玻璃
Jiafei Gu,Xiaoling Liu,Ping Cui et al.
Jiafei Gu et al.
For the treatment of tumor-related bone defects resulting from surgical resection, simultaneous eradication of residual tumor cells and repair of bone defects represent a challenge. To date, photothermal therapy based on photothermal materi...