Functional replacement of fetal bovine serum by extracts from Galdieria sulphuraria in muscle cell culture [0.03%]
热液红藻高尔第虫替代胎牛血清促进肌细胞体外培养功能初探
Svenja Hütker,Hanna Wellkamp,Verena Tellstroem et al.
Svenja Hütker et al.
The development of serum-free culture systems is a major challenge in the large-scale production of cultured meat, where myoblasts must be expanded and differentiated without the use of fetal bovine serum (FBS). FBS remains the gold standar...
Rosmarinic acid/Se4+ self-assembled nanoparticles for combinational therapy of triple-negative breast cancer [0.03%]
玫瑰酸/硒自组装纳米颗粒用于三阴性乳腺癌的联合治疗研究
Chong Qiu,Xinyu Zhou,Qingchao Tu et al.
Chong Qiu et al.
Triple-negative breast cancer (TNBC) presents a formidable clinical challenge due to its aggressive nature and limited treatment options, with immunotherapy often hampered by the immunosuppressive "cold" tumor microenvironment. To address t...
Engineering of green sterilization technology to obtain biocompatible aerogels: Supercritical CO2 versus ethylene oxide and gamma radiation [0.03%]
绿色灭菌技术工程以获得生物相容气凝胶：超临界二氧化碳对乙烯氧化和γ射线的影响
María Carracedo-Pérez,Antonella Caterina Boccia,Inés Ardao et al.
María Carracedo-Pérez et al.
The growing relevance of aerogels in biomedicine demands the choice of compatible sterilization techniques with these materials. Conventional methods, such as ethylene oxide (EO) and gamma radiation (γ-rays) sterilization, have significant...
Nanoplatform for renal ischemia-reperfusion injury repair: Modulating macrophage polarization, oxidative stress, and mitophagy [0.03%]
用于调节巨噬细胞极化、氧化应激和线粒体自噬的肾脏缺血再灌注损伤修复纳米平台
Mu He,Ting Liu,Hongchao Zhao et al.
Mu He et al.
Acute kidney injury (AKI) is a common clinical condition characterized by high morbidity and mortality rates, with a notable lack of effective therapeutic drugs. Complex pathological processes-such as oxidative stress overload, aberrant mac...
A dual-active biological scaffold with in situ loaded Abaloparatide and bone marrow-derived mesenchymal stem cells synergistically regulatory T cell to promote bone regeneration [0.03%]
一种双重活性生物支架通过原位加载艾伯洛帕肽和骨髓间充质干细胞协同调节T细胞促进骨骼再生
Mingyu Jia,Zhihong Chen,Huajian Zhou et al.
Mingyu Jia et al.
Bone defect repair remains a significant challenge faced in clinical practice. Bone tissue engineering has emerged as an effective approach for bone defect repair due to its ample donor source and remarkable repair efficacy. In this study, ...
Advances in functionalized biodegradable biliary stents: From material design to clinical translation [0.03%]
功能性可降解胆道支架研究进展：从材料设计到临床转化
Shuiguo Tang,Rongji Ye,Guanzhi Lai et al.
Shuiguo Tang et al.
Biliary stricture, primarily caused by inflammation, hepatobiliary and pancreatic malignancies and other pathological factors, often leads to impaired bile drainage and subsequent poor clinical outcomes. While biliary stent implantation has...
Paotianxiong polysaccharides as a stabilizer for protein nanoparticles and construction of an enhanced gastric acid-responsive hydrogel for delivery of fisetin to alleviate alcoholic gastric injury [0.03%]
炮天雄多糖作为蛋白质纳米颗粒的稳定剂及构建用于递送矢车菊素以缓解酒精性胃损伤的增强型胃酸响应水凝胶体系
Qiao Ren,Jiaxin Jiang,Chenghao He et al.
Qiao Ren et al.
Long-term excessive alcohol intake can easily lead to gastritis, gastric ulcer, and gastric bleeding. To address fisetin's (FIT) limitations in ameliorating alcohol-induced gastric injury while resolving stability issues of pH-driven albumi...
Nanoparticle-mediated Zn delivery impacts neural protein phosphatase activity [0.03%]
纳米颗粒介导的锌输送影响神经蛋白磷酸酶活性
André Nadais,Carolina Castro,Inês Martins et al.
André Nadais et al.
In recent years, the use of nanoparticles (NPs) in diagnosis and treatment of different disorders has been a matter of intensive research. Due to their physical and chemical properties, zinc oxide nanoparticles (ZnO NP) have been explored i...
Cellular uptake of anisotropic microparticles in 2D and 3D culture systems [0.03%]
各向异性的微颗粒在二维和三维培养系统中的胞吞作用
Navneet Kaur,Annie Scutte,Mary Jean Savitsky et al.
Navneet Kaur et al.
Three-dimensional (3D) cell culture models offer a more physiologically relevant alternative to traditional two-dimensional (2D) cultures by better replicating in vivo microenvironments, including extracellular matrix interactions, cell-cel...
Synthesis of N-substituted phenothiazine styrene monomers for amphiphilic fluorescence nanoparticles: structure-fluorescence relationship, from AIE to ACQ effect and drugs delivery systems [0.03%]
N-取代苯并噻嗪茋单体的合成用于两亲性荧光纳米粒子：从聚集诱导发光到聚集淬灭和药物输送系统效应的关系研究
Zengfang Huang,Xiaotong Zhang,Jinwen Tan et al.
Zengfang Huang et al.
Phenothiazines are highly active and attracting significant attention in various fields including biology and medicine, etc. Herein, several styryl phenothiazine derivatives including VPPA, VPBM, 3PVP and 4PVP were successfully synthesized,...