Sulfated poly(aspartic acid) coatings as next-generation biomimetic interfaces for blood-contacting devices [0.03%]
用于血液接触设备的仿生界面的硫酸化聚(天冬氨酸)涂层作为下一代生物界面
Cuong Hung Luu,Akriti Nepal,Nam-Trung Nguyen et al.
Cuong Hung Luu et al.
The increasing reliance on blood-contacting medical devices underscores the need for materials that minimise thrombosis and inflammation. Devices such as stents and dialysis membranes often face complications related to clot formation and m...
In vitro and ex vivo evaluation of a papain-loaded mucoadhesive buccal patch with potential antifibrotic and anticancer activity [0.03%]
一种具有潜在抗纤维化和抗癌活性的含木瓜蛋白酶粘膜粘附颊贴片的体外和 ex vivo 评价
Nandita Parida,Rekha Rani Kokkanti,Soumyajit Biswas et al.
Nandita Parida et al.
Oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC) are characterized by aberrant extracellular matrix remodeling, chronic inflammation, and limited responsiveness to current local treatment modalities. In this study, we ...
Oral delivery of liraglutide using CPP/hyaluronic acid-modified mesoporous silica nanoparticles: A virus-inspired strategy for intestinal absorption [0.03%]
一种肠道吸收的病毒启发策略：使用CPP/透明质酸修饰的中孔硅纳米颗粒口服递送利拉鲁肽
Narges Shams,Mehdi Esfandyari-Manesh,Mohammad Sharifzadeh et al.
Narges Shams et al.
Oral administration of peptide-based drugs offers improved patient compliance compared to injectable formulations. However, this route is hindered by several physiological barriers like enzymatic degradation, poor intestinal permeability, a...
Lysophosphatidic acid-induced upregulation of exosomal miR-221-3p from corneal stromal cells promotes corneal endothelial healing [0.03%]
角膜基质细胞衍生的富含miR-221-3P的外泌体促进角膜内皮愈合
Hung-Chi Chen,Yi-Jen Hsueh,Yaa-Jyuhn James Meir et al.
Hung-Chi Chen et al.
Corneal transparency maintenance relies on the water-pumping function of the corneal endothelium. Currently, corneal transplantation remains the only available treatment for corneal endothelial dysfunction, therefore, the development of alt...
Thermosensitive nanogel-based oxaliplatin delivery system for synergistic intratumoral radiofrequency chemotherapy [0.03%]
温敏性纳凝胶载奥沙利铂协同瘤内射频热化疗系统
Ling Li,Anna Liu,Cai Wang et al.
Ling Li et al.
To achieve sustained release and prolonged tumor retention of oxaliplatin (OXA), a thermosensitive OXA-loaded poly(N-isopropyl acrylamide-co-acrylic acid) nanogel (PAAs) was developed via a synergistic mixing-stirring method. The formulatio...
Regulation of osteogenic differentiation of boronized Ti6Al4V/HA composite involving TRIP13-PI3K/Akt signaling pathway [0.03%]
硼改性Ti6Al4V/HA复合材料通过TRIP13-PI3K/Akt信号通路调控成骨分化作用研究
Yihong Chen,Xiaojie Chen,Boyu Liu et al.
Yihong Chen et al.
Titanium and its alloys are widely used in dental implants owing to their excellent biocompatibility and corrosion resistance, despite their elastic moduli mismatch with bone and insufficient interfacial bioactivity which often restrict the...
Surface microstructure of PEEK scaffolds regulates osteogenic differentiation via the βPIX-RAC1-NOX1 pathway [0.03%]
PEEK支架表面微结构通过βPIX-RAC1-NOX1途径调节成骨分化
Zijian Yang,Bowen Zhang,Yihao Liu et al.
Zijian Yang et al.
Polyetheretherketone (PEEK) is widely applied in orthopedic implants, yet its intrinsic surface bioinertness limits stable osseointegration. Although a nature solution is modifying its surface to enhance cellular adhesion, other pathways re...
Tao Wang,Yuxuan Chen,Xuyang Zhang et al.
Tao Wang et al.
Breast cancer (BC) remains a global health challenge, with treatment limitations from systemic toxicity, poor drug bioavailability, and multidrug resistance (MDR). Recent advancements in nanotechnology have revolutionized drug delivery syst...
Theranostic platforms for skin tissue engineering: Bridging healing and real-time monitoring [0.03%]
皮肤组织工程的诊疗平台：愈合与实时监测之间的桥梁
Lidia Maeso,Mohammadsadegh Nadimifar,Saptarshi Biswas et al.
Lidia Maeso et al.
Chronic wounds are a major healthcare challenge, contributing to significant morbidity and reduced quality of life while imposing a substantial economic burden on healthcare systems. Traditional wound care approaches often fail to provide r...
Corrigendum to "Evaluating antimicrobial efficacy in medical devices: The critical role of simulating in use test conditions" [Biomater. Adv. 172 (2025), 214241] [0.03%]
关于“评估医疗器械的抗菌功效：模拟实际使用测试条件的关键作用”的勘误[Biomater. Adv. 172 (2025), 214241]
Sofia Wareham-Mathiassen,Mohammed Nateqi,Sai Achyuth Badrinarayanan et al.
Sofia Wareham-Mathiassen et al.
Published Erratum
Biomaterials advances. 2026 Jan 23:214729. DOI:10.1016/j.bioadv.2026.214729 2026