Recent advances in plant polyphenol-based adhesive hydrogels for biomedical applications [0.03%]
基于植物多酚的用于生物医学应用的粘合性水凝胶近期研究进展
Yajun Chen,Xue Guo,Yuxin Zhang et al.
Yajun Chen et al.
Plant polyphenol-based hydrogels have gained widespread attention due to their unique and outstanding properties such as adhesion, antibacterial, self-healing and biocompatibility. The adhesion performance of these hydrogels can be systemat...
Nanoceria-mediated redox modulation for periodontal management: Mechanisms, applications, and challenges [0.03%]
纳米氧化铈介导的牙周疾病氧化还原调控：机制、应用及挑战
Xin Chen,Song Chen,Yi Hou
Xin Chen
Periodontitis is caused by dental plaque that triggers the host immune responses by the dysregulation of reactive oxygen species (ROS), leading to the destruction of local tissues such as gingiva, periodontal ligament, and alveolar bone. Wi...
Thermo-responsive in situ hydrogel enables superior rectal administration and local efficacy of 5-ASA in inflammatory bowel disease [0.03%]
热响应原位水凝胶使5-ASA治疗炎症性肠病的直肠给药性能和局部疗效更优异
Elena Giuliano,Angela Costagliola di Polidoro,Agnese Gagliardi et al.
Elena Giuliano et al.
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract that severely compromises quality of life. First-line therapy with 5-aminosalicylic acid (5-ASA) is limited by poor aqueous solubil...
3D-printed GelMA-Fe-GQD magneto-hydrogel as a smart platform for triple-negative breast cancer hyperthermia [0.03%]
用于三阴性乳腺癌热疗的3D打印GelMA-Fe-GQD磁性水凝胶智能平台
Mohammad Suhaan Dar,Niroj Kumar Sahu
Mohammad Suhaan Dar
Designing multifunctional hydrogels that combine structural tunability with therapeutic responsiveness remains a key challenge in translational cancer nanomedicine. Here, we report the development of a GelMA-Fe-GQDs nanocomposite hydrogel e...
A nanoengineered coating with dual antioxidant and immunomodulatory functions on titanium implants for osteoregeneration in osteoporosis [0.03%]
一种纳米工程涂层具有抗氧化和免疫调节功能可促进骨缺损的骨再生治疗骨质疏松症的钛种植体
Zijian Wang,Rui Yu,Ying Zhou et al.
Zijian Wang et al.
Poor implant-bone integration under osteoporotic conditions remains a critical clinical challenge. The osteoporotic microenvironment, characterized by excessive oxidative stress, immune homeostasis imbalance, and persistent chronic inflamma...
Luteolin/polyvinyl alcohol/sodium alginate hydrogel enhances fibroblast-mediated tissue repair and facilitates pressure injury healing [0.03%]
木犀草素/聚乙烯醇/海藻酸钠水凝胶增强成纤维细胞介导的组织修复并促进压力性损伤愈合
Wenyi Huang,Tongshan Su,Jiacheng Fan et al.
Wenyi Huang et al.
This study aimed to elucidate the mechanism through which luteolin/polyvinyl alcohol/sodium alginate (Lut/PVA/SA) hydrogel promotes the healing of pressure injury (PI), thereby offering optimized strategies for clinical management. Four for...
Construction of growth plate organoids via a layered induction based in vitro 3D cultivation system [0.03%]
基于分层诱导的体外三维培养体系的生长板类器官构建
Xianggang Wang,Pan Li,Mohammad Nour Muselmani et al.
Xianggang Wang et al.
Serious injury to the growth plate often leads to bony bridge formation, resulting in halted long bone growth, angular deformities, and limb length discrepancies. These problems persist unaddressed in the clinic. In this study, we engineere...
Micelle-integrated hydrogel combined with pH-response boosts eye burns therapy by inhibiting neovascularization, regulating inflammation and bacteriostasis [0.03%]
结合pH响应抑制新生血管、调节炎症和抑菌的胶束集成水凝胶眼部烧伤治疗研究
Yahong Li,Xinyuan Wang,Meina Wu et al.
Yahong Li et al.
Corneal neovascularization (CNV) is a sight-threatening pathological process that poses the challenge of controlling inflammation, preventing infection, and thereby inhibiting angiogenesis. To address this, we developed a novel pH-responsiv...
Mechanical instability as a signature of viscoelastic decoupling at the tumor-brain interface [0.03%]
肿瘤-大脑界面粘弹性脱钩的机械不稳定标志
Jan Saip Aunan-Diop,Ancuta Ioana Friismose,Emi Hojo et al.
Jan Saip Aunan-Diop et al.
Brain tumors alter the viscoelastic equilibrium of surrounding tissue, but how these changes shape the mechanics of tumor-brain coupling remains unclear. This study introduces mechanical instability mapping, a voxelwise measure of imbalance...
Use of collagen from marine origin for bone tissue regeneration in preclinical in vivo studies: a systematic review and quality evaluation [0.03%]
预临床在体研究中用于骨组织再生的海洋胶原蛋白的使用：系统评价和质量评估
Mario García-González,Francisco Vidal-Negreira,Antonio González-Cantalapiedra et al.
Mario García-González et al.
The rising demand for safe and effective alternatives for bone regeneration has spurred extensive research into biomaterials derived from marine collagen. This systematic review aimed to evaluate the feasibility of marine collagen-based com...