Constructing Bi2Te3-Ti3C2TX Schottky junction in PCL scaffold to amplify photo-thermal-electricity coupling effect for accelerating cell osteogenic differentiation [0.03%]
构建Bi2Te3-Ti3C2TX肖特基结PCL支架以增强光电热耦合效应从而加速细胞成骨分化
Xiang Chen,Huixing Li,Yidong Zhong et al.
Xiang Chen et al.
Bismuth telluride (Bi2Te3) exhibits great potential in thermoelectric therapy for bone defect repair due to its excellent thermoelectric conversion and electron-phonon decoupling properties. Nonetheless, its therapeutic efficacy is restrict...
Light-directed reprogramming of tumor-associated macrophages via STING agonist delivery [0.03%]
通过STING激动剂递送定向重组肿瘤相关巨噬细胞
Olga I Gusliakova,Lidia V Mikhailova,Olga A Inozemtseva et al.
Olga I Gusliakova et al.
Macrophages play a pivotal role in immune regulation and disease progression through their ability to polarize into pro-inflammatory M1 or anti-inflammatory M2 phenotypes. In solid tumors, tumor-associated macrophages (TAMs) are predominant...
Melt electrowriting of PCL/BaTiO3 composites: Printability, anisotropic mechanical properties, and cytocompatibility [0.03%]
聚己内酯/钛酸钡复合材料的熔融电写技术：可打印性，各向异性力学性能和细胞相容性
Yakui Liu,Dhrmendra Sablaniya,Max von Witzleben et al.
Yakui Liu et al.
Melt electrowriting (MEW) is a less-explored yet promising additive manufacturing technique for fabricating tissue-engineered scaffolds with the designed microarchitecture. One of the significant advantages of MEW is the ability to manufact...
Nanotherapeutic potential of Baicalein-encapsulated hUC-MSC exosomes in Alzheimer's disease: Modulating oxidative stress and neuroinflammation [0.03%]
baicalein-封装的hUC-MSC外泌体治疗阿尔茨海默病的纳米疗法潜力：调节氧化应激和神经炎症
Jing Xu,Ziyan He,Yaoxin Pan et al.
Jing Xu et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by excessive amyloid-β (Aβ) accumulation, neuroinflammation, and oxidative stress. Exosomes derived from human umbilical cord mesenchymal stem cells (hUC-M...
Influence of mechanical properties of agarose hydrogels on bacterial growth and secretory activity [0.03%]
琼胶水凝胶的机械性能对其细菌生长及分泌活性的影响研究
L Dupont,V S Tadimarri,R Buret et al.
L Dupont et al.
Engineered living materials (ELMs) rely on the ability to control cell behavior in material systems. ELMs containing bacteria secreting beneficial molecules are being developed for therapeutic purposes. Using commensal strains embedded in p...
Enhanced permeability and retention (EPR) effect: Advances in nanomedicine for improved tumor targeting [0.03%]
增强渗透与保留(EPR)效应：改善肿瘤靶向的纳米医学进展
Mohammad Sameer Khan,Taha Alqahtani,Humood Al Shmrany et al.
Mohammad Sameer Khan et al.
The enhanced permeability and retention (EPR) effect driven by abnormal tumor vasculature and impaired lymphatic drainage has long been considered a cornerstone of nanomedicine-based cancer therapy. While preclinical studies demonstrate sub...
Development of ellagic acid-derived bismuth MOF for targeted therapy in colitis [0.03%]
一种用于治疗结肠炎的ellagic酸衍生的铋MOFs及其制备方法和应用
Yinan Wang,Xiuxiu Huang,Xiao Luo et al.
Yinan Wang et al.
Oxidative stress plays a key role in inflammatory diseases like colitis, but traditional antioxidants are limited by poor bioavailability and non-specific actions, reducing their effectiveness. This study seeks to overcome these limitations...
A β-Si3N4/HA composite materials with biomimetic mineralized CaCO3 coating promote angiogenesis and bone regeneration through immunomodulation [0.03%]
生物矿化CaCO3涂层的β-Si3N4/HA复合材料通过免疫调节促进血管生成和骨再生
Andi Guo,Hongyu Zhao,Yixuan Zhao et al.
Andi Guo et al.
The local immune microenvironment within bone defects dynamically orchestrates bone regeneration through intricate interactions between immune cells and bone marrow mesenchymal stem cells (BMSCs). Hydroxyapatite (HA), a commonly used biocer...
Ginger extract release from 3D printed calcium phosphate scaffolds for bone regeneration [0.03%]
三维打印钙磷灰石支架中姜提取物的释放促进骨再生
Susmita Bose,Yongdeok Jo,Aditi Dahiya
Susmita Bose
The development of multifunctional bone scaffolds that promote early osteogenesis and angiogenesis is a promising strategy for treating critical-sized bone defects. In this study, 3D-printed tricalcium phosphate (3DP TCP) scaffolds were loa...
Silver-doped MoOx NPs with phytochemicals for photodynamic therapy application: Playing with the sequence of surface modification steps [0.03%]
用于光动力疗法的含银MoOx纳米颗粒与植物化学物质：表面改性步骤顺序的影响
Olena Ivashchenko,Adriana Hvizdošová Annušová,Łukasz Popenda et al.
Olena Ivashchenko et al.
Photodynamic therapy (PDT) is a promising strategy for cancer treatment, employing photosensitizers activated by light to induce cytotoxicity. Hybrid organic-inorganic nanocomplexes, which integrate the unique properties of plasmonic metals...