Depression in children with asthma: Testing a cholinergically mediated "endotype" [0.03%]
哮喘儿童的抑郁：测试一种胆碱能介导的“内表型”
Heather K Lehman,Beatrice L Wood,Quratulain Humayun et al.
Heather K Lehman et al.
Background: Asthma is not a single uniform disease; instead, it comprises various disease sub entities, or "endotypes," with different etiologies and pathophysiologies. As asthma endotypes are discerned, individuals with ...
Drug-induced enterocolitis syndrome with amoxicillin-containing products: A review of cases reported to the FDA adverse event reporting system and published literature [0.03%]
含氨苄西林制品所致药物性肠结肠炎综合征：FDA不良事件报告系统及已发表文献中的病例分析
Maya Beganovic,Rachna Kapoor,S Christopher Jones et al.
Maya Beganovic et al.
Background: Drug-induced enterocolitis syndrome (DIES) is a rare, non-IgE-mediated allergic reaction occurring 1 to 4 hours after drug ingestion. Objectiv...
Kelly Colas,Jennifer Namazy,Diana Johnson et al.
Kelly Colas et al.
Background: Maintaining optimal control of asthma during pregnancy is critical, as poorly controlled asthma is associated with negative health implications for both mother and baby. However, asthma medications are frequen...
Trends over a decade in the prevalence and eliciting dose of peanut and tree nut allergies in Japan [0.03%]
日本十年来花生和树坚果过敏症流行率及致敏剂量的变化趋势
Hitomi Kubota,Tatsuki Fukuie,Sayaka Hamaguchi et al.
Hitomi Kubota et al.
Background: The prevalence of tree nuts allergy is rapidly increasing in Japan, yet the eliciting dose (ED) for tree nuts, particularly in Asian populations, has not been sufficiently investigated. ...
Biomarker-guided IL-5 blockade achieves steroid-free MPO-ANCA seroconversion in EGPA [0.03%]
生物标志物指导的IL-5阻断使EGPA患者无需糖皮质激素治疗即实现MPO-ANCA血清学转换
Osamu Matsuno,Tansri Wibowo,Yutaka Ishida et al.
Osamu Matsuno et al.
This report describes a case of biopsy-confirmed EGPA in which early initiation of mepolizumab, guided by biomarker surveillance, resulted in steroid-free MPO-ANCA seroconversion. These findings suggest a potential steroid-sparing strategy ...
Indoor allergens and endotoxins in relation to cockroach infestations in low-income urban homes [0.03%]
城市低收入家庭中德国小蠊侵害情况下的室内过敏原和内毒素水平关系研究
Madhavi L Kakumanu,Zachary C DeVries,Richard G Santangelo et al.
Madhavi L Kakumanu et al.
Background: Cockroach allergens are well recognized as important risk factors in the development and prevalence of allergic rhinitis and asthma in children, especially in low-income urban households. The German cockroach ...
Specialist care improves diagnosis and treatment for patients with chronic spontaneous urticaria: A real-world survey [0.03%]
专科护理可提高慢性自发性荨麻疹患者的诊断和治疗水平-一项真实世界调研
Giselle Mosnaim,James Hetherington,Aaron Keal et al.
Giselle Mosnaim et al.
Background: Although effective treatments and guidelines for chronic spontaneous urticaria (CSU) are available, patients often experience diagnostic delays and undertreatment. ...
Sublingual immunotherapy in children with asthma: A population-based register study [0.03%]
哮喘儿童舌下免疫治疗：基于人群的注册研究
Jon R Konradsen,Cecilia Lundholm,Anna M Hedman et al.
Jon R Konradsen et al.
Background: Daily sublingual immunotherapy (SLIT) for 3 years reduces symptoms of allergic disease and induces tolerance. Real-life data from children with asthma receiving SLIT are scarce. ...
Berotralstat effectiveness and safety in patients with hereditary angioedema with normal C1 inhibitor [0.03%]
补体C1抑制物正常的遗传性血管水肿患者的伯卢司特疗效和安全性
Matthew S Buckland,Isabelle Boccon-Gibod,Claire De Moreuil et al.
Matthew S Buckland et al.
Background: Hereditary angioedema (HAE) with normal C1 inhibitor (nC1-INH) is the least common endotype of HAE, a rare disorder with localized, intermittent attacks of soft tissue swelling. Prophylactic treatments are ava...
Allergy and dermatology US treatment guidelines review for adults with atopic dermatitis [0.03%]
成人特应性皮炎过敏和皮肤病美国治疗指南综述
Constance Bindernagel,Richard Bindernagel,Baylee Fulford et al.
Constance Bindernagel et al.
Background: Atopic dermatitis (AD) is a chronic, inflammatory condition that affects patients of all ages. Dermatologists and allergists often treat these patients, with each group of specialists following distinct sets o...