Identification of predictive factors for clinical remission and comparison of 3 definitions in Japanese patients with severe asthma treated with biologics [0.03%]
重度哮喘生物制剂治疗患者的临床缓解预测因素识别及三种定义的比较研究
Takanori Numata,Susumu Saito,Keitaro Okuda et al.
Takanori Numata et al.
Background: The definition and predictive factors of clinical remission (CR) in patients with severe asthma are unclear. Objective: We ...
Evaluation of drug-induced lymphocyte stimulation test in mesalazine-associated allergic drug reaction [0.03%]
5-氨基水杨酸所致药物过敏反应的淋巴细胞刺激试验诊断价值评估
Naoto Fukasawa,Hiroki Kiyohara,Takeya Adachi et al.
Naoto Fukasawa et al.
Background: 5-Aminosalicylic acid (5-ASA) is a fundamental drug for UC management; however, adverse reactions can lead to poor clinical outcomes and increased health care costs. No objective tests currently exist to predi...
Real-life safety of peanut oral immunotherapy: Results from a French multicenter observational study [0.03%]
法国多中心观察性研究中的真实世界口服免疫疗法的花生过敏治疗安全性研究结果分析
Elodie Michaud,Flore Amat,Céline Lambert et al.
Elodie Michaud et al.
Background: Peanut oral immunotherapy (POIT) has been widely used in France for more than 10 years. However, the overall "real-life" safety of POIT has not been evaluated to date. ...
An opportunity to improve the quality of care for patients with chronic spontaneous urticaria: A reimagined 3-step real-world study protocol [0.03%]
改善慢性自发性荨麻疹患者护理质量的机会：重新构想的三项现实世界研究方案
Giselle Mosnaim,Sarbjit S Saini,Michael Holden et al.
Giselle Mosnaim et al.
Background: Chronic spontaneous urticaria (CSU) is a debilitating condition of the skin that leads to significant negative impacts on patient quality of life and psychological well-being. Given the complexities of the dis...
Potential for gradual tolerance acquisition in egg yolk-induced FPIES: A case series [0.03%]
以卵黄诱导的FPIES病例系列研究中逐渐产生耐受性的潜力
Tomoaki Kunitsu,Kana Hamanaka,Midori Tagaya et al.
Tomoaki Kunitsu et al.
Background: Food protein-induced enterocolitis syndrome (FPIES) caused by egg yolk is increasingly recognized in Japan, yet the optimal timing for oral food challenge (OFC) and the process of tolerance acquisition remain ...
Specialist physician perspectives on clinical decision support to address secondary vaccine hesitancy [0.03%]
专科医师对临床决策支持的看法，以应对二次疫苗犹豫问题
Anjali Nemorin,Dylan T Norton,Chloe V Green et al.
Anjali Nemorin et al.
Background: Vaccines are an evidence-based intervention that mitigates the impact of infections, yet many Americans indicate hesitancy toward receiving vaccines. One of the most common reasons for this is the potential fo...
High levels of nonblocking anti-interferon and anticytokine autoantibodies in individuals with mRNA vaccine-induced systemic allergic reactions [0.03%]
高非干扰素和抗细胞因子自身抗体水平与mRNA疫苗诱导的全身过敏反应有关
Muge Kalaycioglu,Allan Feng,Shaurya Dhingra et al.
Muge Kalaycioglu et al.
Background: Hypersensitivity reactions following coronavirus 2019 disease (COVID-19) mRNA vaccination, although rare, have raised public concern and contributed to vaccine hesitancy. The underlying mechanisms and cofactor...
Differences in immunoglobulin utilization when treating patients with primary immune disease in the United States [0.03%]
美国治疗原发性免疫疾病患者时免疫球蛋白使用的差异性
Roxanna Farzad,Mei-Sing Ong,Jocelyn R Farmer et al.
Roxanna Farzad et al.
Background: Primary immune diseases (PI) encompass over 550 disorders that are associated with substantial risk of mortality and morbidity. Emerging evidence demonstrates significant survival disparities in PI among racia...
Rising trends in infant ER encounters for food-induced allergic reactions in the era of early allergenic food introduction [0.03%]
早期引入致敏食物时代的婴幼儿因食品诱发过敏反应而急诊就诊的新趋势
Aaron Chin,Ali Doroudchi,Derek C Pham et al.
Aaron Chin et al.
Background: Allergic reactions to food are a leading cause of pediatric emergency room (ER) visits. National guidelines now recommend early introduction of allergenic foods; however, whether these changes have affected ER...
Patient perspectives of allergic rhinitis and allergen immunotherapy: A qualitative study [0.03%]
变应性鼻炎患者的特异免疫治疗态度及影响因素的定性研究
Joshua Jacob,Caroline Joyce,Melanie Lloyd et al.
Joshua Jacob et al.
Background: Allergic rhinitis (AR) is a highly prevalent condition associated with significant morbidity globally. Few recent studies have detailed the experiences of sufferers and explored their perspectives of treatment...