Associations between dietary intake and asthma outcomes: Evidence from pooled analysis in two independent multiethnic Asian cohorts [0.03%]
基于两项独立的多民族亚洲队列研究汇总分析探讨饮食摄入与哮喘结局之间的关联性
Jun Jie Lim,Zongxun Huang,Yu Qi Lee et al.
Jun Jie Lim et al.
Background: Asthma is a chronic respiratory condition that poses significant public health challenges worldwide, including Singapore. Objective: ...
Distinct blood transcriptomic profiling underlying asthma establishment and exacerbation [0.03%]
与哮喘建立和加重相关的不同血液转录组特征
Baojun Wu,Mao Yang,Donglei Hu et al.
Baojun Wu et al.
Background: Non-Hispanic Black individuals are disproportionately affected by asthma and severe asthma exacerbations. To elucidate asthma pathogenesis, it is essential to understand the dysregulated gene expression patter...
Real-world impact of mepolizumab on pediatric and adolescent patients with severe asthma [0.03%]
美柏利珠单抗对重度哮喘患儿的现实世界影响
Michelle L Hernandez,Tom Corbridge,François Laliberté et al.
Michelle L Hernandez et al.
Background: Real-world evidence on the effectiveness of mepolizumab in children and adolescents with severe asthma (SA) is limited. Objective: ...
Anesthetic procedure outcomes after initial perioperative anaphylaxis: A retrospective multicenter US review [0.03%]
美国多中心回顾性研究首次围手术期过敏的麻醉处理及结局
Saiyara S Shama,Ricardo J Estrada-Mendizabal,Christine R F Rukasin et al.
Saiyara S Shama et al.
Background: Limited information exists regarding outcomes during repeat surgical procedures in patients with perioperative anaphylaxis (POA). Although current guidelines recommend that future procedures be guided by aller...
Mutations of MRGPRX2, drug sensitivity, and genetic markers related to disease [0.03%]
MRGPRX2突变、药物敏感性及与疾病相关的遗传标志物
Subashini Hemamala Ratnayake,Kanishka Senarath,Dakshika Gangani et al.
Subashini Hemamala Ratnayake et al.
Mast cells (MCs) express the novel class A Mas-related G protein-coupled receptor X2 (MRGPRX2). Additionally, neurons and other leukocytes including basophils express MRGPRX2. MC activation dependent on IgE is a well-established and extensi...
Improved food allergy and anaphylaxis knowledge and comfort among internal medicine residents following a brief educational intervention [0.03%]
一项简短的教育干预措施改善了内科住院医师对食物过敏和过敏性休克的知识和应对能力
Stephanie Jeong,Scott H Sicherer
Stephanie Jeong
Background: Self-injectable epinephrine (SIE) is the first line of defense against anaphylaxis, a potentially life-threatening allergic reaction commonly triggered by food. Internal medicine residents play a crucial role ...
Evaluating the concordance of pollen forecasting apps against automated pollen monitoring: A single-site experience [0.03%]
花粉预报应用程序与自动化花粉监测的一致性评估：单一地点的经验报告
Freddy Gonzalez,Christina E Ciaccio,Sharmilee M Nyenhuis
Freddy Gonzalez
Background: Individuals with allergic rhinitis and asthma rely on accurate pollen forecasts to avoid allergen exposure and manage symptoms. However, many widely used weather and health applications (apps) use manual polle...
Prospective study of basophil activation test in suspected perioperative transfusion anaphylaxis [0.03%]
疑似围术期输血过敏患者外周血中肥大细胞活化功能的前瞻性研究
Yasuhiro Amano,Tasuku Fujii,Natsumi Kameyama et al.
Yasuhiro Amano et al.
Background: Identifying the causative blood product in cases of suspected perioperative transfusion anaphylaxis is challenging because no confirmatory skin tests exist, and few blood-based diagnostic tests are available, ...
Evidence for dysbiosis in the gut microbiome of patients with systemic mastocytosis [0.03%]
系统性肥大细胞增多症患者肠道微生物组失调的证据
Lauren E Krausfeldt,Vivian Cao,Richard Rodrigues et al.
Lauren E Krausfeldt et al.
Background: Limited research studies have investigated the role of the gut microbiome in systemic mastocytosis (SM), which is characterized by an aberrant expansion of clonal mast cells in specific tissues including the s...
Untangling obese asthma: Design of proof-of-concept study of semaglutide in poorly controlled asthma [0.03%]
肥胖伴支气管哮喘的病因探究：利拉鲁肽治疗控制不佳的哮喘概念验证性研究的设计
Alessandra Tomasello,Leonard B Bacharier,Patrice M Becker et al.
Alessandra Tomasello et al.
Background: The intersection of obesity and asthma represents a complex clinical challenge characterized by increased symptom burden, reduced treatment efficacy, and multifactorial pathophysiology. Obesity-associated asth...