Safety and efficacy of graded dosing of Pfizer-BioNTech mRNA COVID-19 vaccine after an immediate hypersensitivity reaction to first dose [0.03%]
辉瑞生物科技公司mRNA新冠疫苗首次接种后即刻发生过敏反应者分阶段接种的安全性和有效性
Prudhvi Regula,David Rosenstreich,Elina Jerschow et al.
Prudhvi Regula et al.
Current guidelines do not recommend subsequent mRNA COVID-19 vaccination in patients who experience immediate allergic reactions to the first dose. Our findings indicate that graded dosing of this vaccine is safe, efficacious, and useful fo...
Cord blood sphingolipids are associated with atopic dermatitis and wheeze in the first year of life [0.03%]
脐带血鞘脂与生命第一年内特应性皮炎和喘息的关系
Aki Hoji,Rajesh Kumar,James E Gern et al.
Aki Hoji et al.
Background: Allergen-sensitized pregnant mice have increased plasma levels of the lipids β-glucosylceramides (βGlcCers) that are transplacentally transferred to the fetus, increased subsets of proinflammatory dendritic ...
Prenatal exposure to Hurricane Maria is associated with an altered infant nasal microbiome [0.03%]
prenatal暴露于飓风玛丽亚与婴儿鼻微生物群改变有关
Sandra Lee,Ai Zhang,Midnela Acevedo Flores et al.
Sandra Lee et al.
Background: Prenatal adverse exposures have been associated with increased risks of development of respiratory diseases in children. The infant nasal microbiome is an important mechanism and indicator. ...
Vaccination counseling with and without excipient skin testing in patients with suspected allergic reactions to mRNA COVID-19 vaccines and patients with atopy [0.03%]
含辅料皮肤试验和不含辅料皮肤试验在怀疑对mRNA新冠疫苗产生过敏反应的患者及特应性患者中的接种咨询作用
Dilawar Khokhar,Kelly M O&#x;Shea,Cem Akin et al.
Dilawar Khokhar et al.
Background: Allergic reactions have been reported with mRNA vaccines for COVID-19 prevention. Patients perceived to be at higher risk for a reaction may be referred to an allergist, although evaluation strategies may diff...
Lessons learned from the use of COVID-19 convalescent plasma at Kaiser Permanente [0.03%]
凯萨医疗机构COVID-19恢复期血浆使用经验教训
Kevin Tse,Qiaoling Chen,Ariadna Padilla et al.
Kevin Tse et al.
Background: In April 2020, the Mayo Clinic helped establish the US Food and Drug Administration Expanded Access Protocol for COVID-19 (coronavirus disease 2019) convalescent plasma (CCP). The effectiveness of CCP in the p...
Stability of diluted chlorhexidine for skin testing in drug allergy evaluations [0.03%]
稀释氯己定皮肤试验在药物过敏评估中的稳定性研究
Background: Chlorhexidine gluconate (CHX), a common cause of perioperative anaphylaxis, is frequently used for skin testing in allergy evaluations. Although CHX's maximal nonirritating concentrations are known, the stabil...