When antibiotics turn red: A case of piperacillin-tazobactam-induced baboon syndrome [0.03%]
当抗生素变红——一例哌拉西林他唑巴坦所致类猿人综合征病例报告
Marta Bernaola,Jaime Bernaola,Patricia Majano et al.
Marta Bernaola et al.
Symmetric drug-related intertriginous and flexural exanthema, also known as baboon syndrome, is a rare cutaneous adverse drug reaction that is classified as a delayed type IV hypersensitivity reaction mediated by T lymphocytes and character...
Circulating eosinophils in patients with hypereosinophilic syndrome have heterogeneous immunophenotypes [0.03%]
异形淋巴细胞增多综合征患者的循环嗜酸性粒细胞具有不同的免疫表型特征
Krishan D Chhiba,Richard Kasjanski,Michelle A Makiya et al.
Krishan D Chhiba et al.
Background: Hypereosinophilic syndromes (HES) encompass a heterogeneous group of disorders characterized by blood and/or tissue hypereosinophilia. Despite recent advances, the diagnosis and management of HES remain challe...
Targeting CXCR1/2 suppresses TH2/TH17 cell responses and inhibits dual-pathology allergic lung inflammation [0.03%]
CXCR1/2抑制剂可通过抑制TH2和TH17反应治疗合并症哮喘
Koa Hosoki,Annamalai Govindhan,John M Knight et al.
Koa Hosoki et al.
Background: Many chronic inflammatory diseases are driven by TH2 and TH17 immune responses and represent a major public health burden. While monoclonal antibodies against individual TH2 or TH17 cytokines or receptors show...
The Michigan Sibling Immunity Birth Study (M-SIBS): Study design protocol for a unique food allergy birth cohort [0.03%]
密歇根同卵双胞胎免疫出生研究(M-SIBS):独特食物过敏出生队列的研究设计方案
Kelly M OShea,Elizabeth Brooks,Nancy Polmear-Swendris et al.
Kelly M OShea et al.
Background: Food allergy is a rapidly escalating public health concern, yet the biologic pathways that link early-life exposures with disease onset remain poorly defined. No existing food-allergy birth cohort has yet pair...
Evaluating penicillin allergy clinical decision-making tools to enhance penicillin allergy delabeling [0.03%]
评估青霉素过敏临床决策工具以增强青霉素再标签化
Chang Su,Ami P Belmont,Moeun Son et al.
Chang Su et al.
Background: Patient-reported penicillin allergy is associated with adverse outcomes. Objective: We aimed to evaluate clinical decision-...
Cycling biologic therapy with tezepelumab and mepolizumab for eosinophilic otitis media and eosinophilic pneumonia in a patient with asthma [0.03%]
用于治疗哮喘患者的嗜酸性中耳炎和嗜酸性肺炎的Tezepelumab与Mepolizumab交替生物疗法
Osamu Matsuno,Kayoko Kawashima,Yukiko Hanada et al.
Osamu Matsuno et al.
Sequential use of biologic therapies such as tezepelumab and mepolizumab may represent a steroid-sparing and effective treatment approach for managing distinct eosinophilic disorders, including eosinophilic pneumonia and eosinophilic otitis...
Sublingual allergen immunotherapy in immunosuppressed rheumatoid arthritis patients: Safety and clinical outcomes [0.03%]
免疫抑制的类风湿关节炎患者舌下过敏免疫治疗的安全性及临床疗效
Yoshiaki Kobayashi,Daiki Nakagomi,Shunichiro Hanai et al.
Yoshiaki Kobayashi et al.
Background: Allergen immunotherapy (AIT) is an effective disease-modifying treatment for allergic rhinitis. However, autoimmune diseases such as rheumatoid arthritis (RA) are traditionally considered relative contraindica...
Subacute large bowel obstruction as an unusual presentation of selective IgA deficiency [0.03%]
选择性IgA缺乏导致亚急性结肠梗阻1例报告
Elizabeth Forouzanfar,Beena Nair,Pavaladurai Vijayadurai et al.
Elizabeth Forouzanfar et al.
Nodular lymphoid hyperplasia (NLH) is a rare, benign condition of lymphoid proliferation within the gastrointestinal tract. NLH is a recognized feature of specific immunodeficiency syndromes, including common variable immunodeficiency and s...
Single-nucleus RNA sequencing identifies conserved structural cell programs in allergic lung inflammation [0.03%]
单核RNA测序识别过敏性肺部炎症中保守的结构细胞程序
Annamalai Govindhan,Aakash Sur,Koa Hosoki et al.
Annamalai Govindhan et al.
Background: Lung structural cells contribute to allergic airway inflammation; however, the lung cell type that mounts the most vigorous early transcriptional response to allergen exposure remains unclear. In this study, w...
Prevalence of adverse reactions and food allergies in Colombia: Cross-sectional national study [0.03%]
哥伦比亚不良反应和食物过敏的流行情况:横断面全国研究
Jorge Sánchez,Laura Osorio,Javier Estarita et al.
Jorge Sánchez et al.
Background: The prevalence of food allergy (FA) has been widely studied in developed countries but has been less explored in Latin American countries, where the population has unique cultural conditions, which influence d...