Hereditary angioedema attack trends among patients maintained on lanadelumab long-term prophylaxis [0.03%]
长期使用Lanadelumab预防治疗的HH患者发作情况趋势分析
Maeve O&#x;Connor,Joshua Jacobs,Laura Panattoni et al.
Maeve O&#x;Connor et al.
Background: Longitudinal studies using real-world data are needed to assess the effectiveness of long-term prophylaxis (LTP) for hereditary angioedema (HAE) during successive years of treatment. ...
Cumulative genetic risk for asthma contributes to disease severity in children with asthma [0.03%]
哮喘患儿的累计遗传风险贡献于疾病严重程度
Matthew Dapas,William Wentworth-Sheilds,Emma E Thompson et al.
Matthew Dapas et al.
Background: Childhood-onset asthma is highly heritable, with nearly 200 risk loci identified in genome-wide association studies. Aggregated polygenic risk scores (PRSs) can be used to quantify genetic predisposition to as...
Biologic readiness: Improving tuberculosis screening in an adult allergy and immunology clinic [0.03%]
生物医学准备情况：改善成人变态反应和免疫学门诊的结核病筛查
Kimberly Lovie Murdaugh,Alexis Flen,Raphaela Martina C Pineda et al.
Kimberly Lovie Murdaugh et al.
Background: In outpatient allergy settings serving historically underserved populations, compliance with Mycobacterium tuberculosis (TB) screening and documentation remains challenging. ...
Extended multisystem manifestations of hereditary α-tryptasemia in an allergy center cohort [0.03%]
过敏诊疗中心患者中遗传性α-胰蛋白酶血症的多系统表现扩展现象
Daniel Koch,Friederike Wortmann,Andreas Recke et al.
Daniel Koch et al.
Background: Hereditary α-tryptasemia (HαT) is a common autosomal-dominant trait caused by additional copies of the gene TPSAB1 encoding for α-tryptase. This inheritance is the most common etiology for elevated basal se...
The AIM4 Next Step study: Comparing inhaled corticosteroid dose escalation to dupilumab in patients with uncontrolled asthma and type 2 inflammation [0.03%]
AIM4下一步研究：比较哮喘未得到控制且存在2型炎症患者的吸入皮质类固醇递增剂量与Dupixent疗法
William W Busse,Melissa Iammatteo,Mena Soliman et al.
William W Busse et al.
Background: The Global Initiative for Asthma recommends patients with asthma uncontrolled on medium-dose inhaled corticosteroid (ICS) plus long-acting β2-agonist (LABA) therapy to first escalate their ICS dose before con...
Turning vaccine allergy CDSS into a global trust pipeline: Equity, auditability, and workflow safety [0.03%]
从疫苗过敏CDSS到全球信任管道：公平性、可审核性和工作流程安全
Mulavagili Srikanth,Mulavagili Vijayasimha
Mulavagili Srikanth
Simon Doré,Louis Marois
Simon Doré
This rare case of mango-dependent exercise-induced anaphylaxis underscores the role of cofactors and illustrates the diagnostic challenges in identifying uncommon food-dependent exercise-induced anaphylaxis triggers. ...
Knowledge among primary care physicians on urticaria treatment: Impact of educational interventions [0.03%]
初诊医师对荨麻疹治疗知识的了解：教育干预的影响
Jorge Sánchez,Ana Caraballo,Jaime Ocampo et al.
Jorge Sánchez et al.
Background: Primary care physicians (general practitioners, family physicians, emergency physicians, among others) are often the first point of medical contact for patients with urticaria. Appropriate initial management e...
Stability of proton pump inhibitors for use in hypersensitivity evaluation [0.03%]
质子泵抑制剂在过敏性评价中使用的稳定性
Troy Wanandy,Simon A Handley,Rahul P Patel et al.
Troy Wanandy et al.
Background: Serious adverse drug reactions, including anaphylaxis and hypersensitivity reactions to proton pump inhibitors (PPIs), have been reported and are expected to rise as a result of their widespread use and over-t...
Chronic spontaneous urticaria as an autoimmune feature in common variable immunodeficiency [0.03%]
常见变量免疫缺陷综合征的慢性自发性荨麻疹(autoimmune特征)
E C A Korevaar,A F Karim,V A S H Dalm
E C A Korevaar
In patients with chronic spontaneous urticaria, especially when it is accompanied by recurrent infections or reduced immunoglobulin levels, analysis for common variable immunodeficiency should be considered. Early diagnosis of common variab...