Effectiveness and safety of algorithm for treating pregnant women with syphilis and history of immediate allergy to penicillin [0.03%]
应用于梅毒孕妇且有青霉素即刻过敏史患者治疗的算法的有效性和安全性
Bruna Gehlen,André Feodrippe,Juliana Fóes Bianchini Garcia et al.
Bruna Gehlen et al.
Background: Penicillin is the only proven effective treatment for pregnant women with syphilis. Objective: We evaluated the efficacy an...
Elizabeth S Brunner,Jeffrey M Chambliss,Timothy G Chow
Elizabeth S Brunner
Background: Skin testing is an important component of evaluating Hymenoptera sensitization in patients presenting with a suspected Hymenoptera systemic reaction. Accelerated skin testing protocols have been reported in ad...
Identifying therapeutic targets for allergic asthma through atopic dermatitis-associated genetic mechanisms [0.03%]
通过特应性皮炎相关遗传机制识别过敏性哮喘的治疗靶点
Yuping Pu,Jundong Liu,Adam N Bennett et al.
Yuping Pu et al.
Background: Allergic asthma (AA) is a chronic inflammatory disease with limited effective treatments, often co-occurring with atopic dermatitis (AD). Epidemiologic studies have shown a strong association between AD and AA...
Effectiveness of indacaterol/glycopyrronium/mometasone for refractory asthmatic cough after switching from inhaled corticosteroid/long-acting β2-agonist therapy [0.03%]
三联吸入制剂治疗难治性哮喘咳嗽的疗效及机制研究
Akio Niimi,Hiroyuki Ohbayashi,Hitoshi Asamoto et al.
Akio Niimi et al.
Background: Cough is a major symptom in poorly or partially controlled asthma, which persists despite treatment, thus impairing quality of life. Objective...
Idiopathic hypereosinophilic syndrome: Potential pathologic somatic gene variants identified by exome sequencing [0.03%]
基于外显子组测序的原发性高嗜酸粒细胞综合征患者潜在病理体克基因变异的研究
Alejandro Ferrer,Mrunal Dehankar,Saurabh Baheti et al.
Alejandro Ferrer et al.
Background: Hypereosinophilic syndrome (HES) is a rare group of disorders characterized by eosinophilia in blood and/or tissues. The etiology of HES is largely unknown. Characterizing the molecular pathophysiology of HES ...
Clinical and pathophysiological roles of lower lobe-dominant mucus plugs on computed tomography in patients with asthma with and without bronchiectasis [0.03%]
哮喘伴或不伴有支气管扩张患者中，CT下叶为主部分黏液栓的临床及病理生理作用研究
Naoya Tanabe,Hisako Matsumoto,Natsuko Nomura et al.
Naoya Tanabe et al.
Background: Despite the clinical relevance of mucus plugging, the role of spatial distribution of mucus plugs remains unclear in patients with asthma. Obj...
Mapping allergy research: A comprehensive visual and bibliometric analysis of socioeconomic and quality-of-life dimensions [0.03%]
过敏研究的地图：经济和社会生活质量维度的可视化和文献计量综合分析
Polat Goktas,Nicholas L Rider,Lavanya Diwakar
Polat Goktas
Background: The increasing prevalence of allergic diseases has increased attention to their socioeconomic impact and health-related quality of life. Yet, research in this domain remains dispersed and underrepresented acro...
Clinical recommendations for diagnosis and management of Mendelian susceptibility to mycobacterial disease in resource-limited settings [0.03%]
资源匮乏地区的麻风分枝杆菌易感性遗传疾病的诊断和管理的临床建议
Helena Cornelissen,Brigitte Glanzmann,Ansia van Coller et al.
Helena Cornelissen et al.
Background: Mendelian susceptibility to mycobacterial disease (MSMD) is a rare inborn error of immunity caused by defects in IL-12 or IFN-γ signaling pathways, essential for intracellular pathogen control. While classica...
Prevalence and sensitization of pollen-food allergy syndrome among adolescents in Tokyo [0.03%]
东京地区青少年花粉-食物过敏综合症的流行和致敏情况
Tomoyuki Kiguchi,Tomoki Yaguchi,Tatsuki Fukuie et al.
Tomoyuki Kiguchi et al.
Background: Allergic rhinitis and pollen sensitization typically increase with age; however, longitudinal data on the prevalence of pollen-food allergy syndrome (PFAS) among Japanese adolescents are limited. ...
Protocol design for the ACTIVATE clinical trial: Exposure to vaginal microbiome in cesarean-delivered infants at high risk for allergies [0.03%]
ACTIVATE临床试验的协议设计：通过剖宫产分娩的高过敏风险婴儿接触阴道菌群暴露方案
Angela J Tsuang,Sharon A Chung,Lisa M Wheatley et al.
Angela J Tsuang et al.
Background: Food allergy is increasingly common in the United States. Studies suggest that rising cesarean delivery rates are associated with many immune disorders, including allergic diseases. A preceding proof-of-concep...