Intraoperative methadone for postoperative pain in adult patients undergoing tonsillectomy-a randomised controlled trial [0.03%]
成人扁桃体切除术患者术中使用吗啡类止痛药甲太东治疗术后疼痛的随机对照试验
Michael Bøndergaard,Peter Gaarsdal Uhrbrand,Tutku Karaca et al.
Michael Bøndergaard et al.
Background: Tonsillectomy is a common procedure often associated with severe postoperative pain. This study hypothesised that methadone would provide superior postoperative pain relief and reduced opioid consumption compa...
Derivation and internal-external validation of clinical prediction model for postoperative clinically important hypotension in patients undergoing noncardiac surgery: an international prospective cohort study [0.03%]
非心脏手术后患者术后重要低血压的临床预测模型的派生及内部和外部验证：一项国际前瞻性队列研究
Stephen Su Yang,German Malaga,Maria Lazo-Porras et al.
Stephen Su Yang et al.
Background: Intraoperative and postoperative hypotension are associated with myocardial injury/infarction, stroke, acute kidney injury, and death. Because of its prolonged duration, postoperative hypotension contributes m...
Bader Almodibeg,Jungwoo Kang,Patrice Forget
Bader Almodibeg
Persistent opioid use after surgery is a growing concern, with existing reviews lacking strong predictors beyond prior opioid use. This scoping review aimed to identify knowledge gaps for future research, particularly regarding the impact o...
Is chronic inflammation a risk factor for perioperative myocardial injury or heart failure in pancreatic surgery patients? [0.03%]
慢性炎症是胰腺手术患者围手术期心肌损伤或心力衰竭的危险因素吗？
Ted Reniers,Thijs Rettig,Laura van Zeggeren et al.
Ted Reniers et al.
Background: Chronic inflammation is associated with cardiovascular disease. Whether cardiac risk is increased in surgical patients with chronic inflammation is unknown. We hypothesised that preoperative interleukin 6 (IL-...
Cost-effectiveness analysis of anaesthesia regimens for paediatric strabismus surgery based on multicentre retrospective cohort data from Japan [0.03%]
基于日本多中心回顾性队列数据的儿童斜视手术麻醉方案的成本效益分析
Soichiro Obara,Taiki Kojima,Yusuke Yamauchi et al.
Soichiro Obara et al.
Background: Postoperative vomiting (POV) after paediatric strabismus surgery poses both clinical and economic challenges. This study evaluates the cost-effectiveness of different anaesthesia regimens, focusing on the addi...
Preoperative submaximal cardiopulmonary exercise testing and its association with early postoperative complications [0.03%]
围术前亚极量心肺运动试验与术后早期并发症的关系
Zyad J Carr,Jean Charchaflieh,Andres Brenes-Bastos et al.
Zyad J Carr et al.
Background: Early postoperative complication risk prediction would enhance perioperative surveillance and resource allocation. Reports have described brief submaximal cardiopulmonary exercise testing (CPET) for the routin...
Evaluating the risks and benefits of continuing versus withholding renin-angiotensin system inhibitors: a systematic review and meta-analysis with trial sequential analysis [0.03%]
继续使用肾素-血管紧张素系统抑制剂与停用该类药物的风险和收益评估：系统评价和meta分析及试验序贯分析
Laila Shalabi,Ahmed Ibrahim,Sofian Zreigh et al.
Laila Shalabi et al.
Background: The best perioperative management of renin-angiotensin system inhibitors (RASi) in patients undergoing noncardiac surgery has been an ongoing debate as a result of inconclusive previous studies and insufficien...
Trends in paediatric anaesthesia research publications and the impact of author sex, country of origin, topic, and external funding [0.03%]
儿科麻醉研究论文的出版趋势及其作者性别、来源国、主题和外部资金的影响
Andy Jeon,Aine Sommerfield,Britta S von Ungern-Sternberg
Andy Jeon
Background: The current research landscape has become increasingly competitive with approximately 35% of submitted manuscripts accepted for publication by peer-review journals. It is known that studies with certain 'favou...
A bundle to prevent postinduction hypotension in high-risk noncardiac surgery patients: the ZERO-HYPOTENSION single-arm interventional proof-of-concept study [0.03%]
一种预防高危非心脏手术患者术诱导期低血压的药物组合包：一项关于“零低血压”的单臂干预概念验证性研究
Kristen K Thomsen,Alina Kröker,Linda Krause et al.
Kristen K Thomsen et al.
Background: Postinduction hypotension is common and associated with organ injury but might be largely preventable by careful anaesthetic management. We thus aimed to quantify the severity and duration of postinduction hyp...
Exploratory randomised trial of tranexamic acid to decrease postoperative delirium in adults undergoing lumbar fusion-a trial stopped early [0.03%]
降解腰椎融合术后成人术后谵妄的氨甲环酸探索性随机试验-一项提前终止的试验
Bradley J Hindman,Catherine R Olinger,Royce W Woodroffe et al.
Bradley J Hindman et al.
Background: Postoperative delirium may be mediated by systemic inflammation and neuroinflammation. By inhibiting the proinflammatory actions of plasmin, tranexamic acid (TXA) may decrease postoperative delirium. To explor...