GLP-1 receptor agonist semaglutide reduces appetite while increasing dopamine reward signaling [0.03%]
索马鲁肽激活GLP-1受体减少摄食同时增加多巴胺的奖赏信号
Karlijn L Kooij,Derek IJsbrand Koster,Emma Eeltink et al.
Karlijn L Kooij et al.
Semaglutide, a glucagon-like peptide-1 receptor agonist, is an effective drug reducing body weight and decreasing motivation for palatable food. The mechanisms underlying its effects on food reward remain unclear. We aimed to determine the ...
What influences food choices in anorexia nervosa? Disentangling cognitive and emotional components of decision-making by translational research [0.03%]
进食障碍中的食物选择受什么影响？通过转化研究来区分决策过程中的认知和情感成分
Laura Di Lodovico,Héloise Hamelin,Lucas DeZorzi et al.
Laura Di Lodovico et al.
Anorexia nervosa is a serious mental illness characterized by voluntary restriction of food intake and avoidance of high-calorie food. Anxiety, highly comorbid with anorexia nervosa, appears to be a significant, yet underexplored, factor af...
Safety pharmacology of acute psilocybin administration in healthy participants [0.03%]
健康受试者单次使用裸盖菇素急性给药的安全药理学研究
Isabelle Straumann,Friederike Holze,Anna M Becker et al.
Isabelle Straumann et al.
Psilocybin is being studied for its therapeutic potential in various mental health disorders, such as depression, anxiety, and addiction. Initial studies suggested that psilocybin is generally safe when used under controlled conditions, but...
The dynamic influence of nutrition on prolonged cognitive healthspan across the life course: A perspective review [0.03%]
营养对生命全程持久认知健康跨度的动态影响：述评
Curie Kim,Natalia Schilder,Katie Adolphus et al.
Curie Kim et al.
Cognitive function undergoes a dynamic trajectory across the lifespan, influenced by multifaceted mechanisms encompassing genetics, lifestyle, and environmental factors. This review explores the impact of nutrition, specifically energy and ...
No association between serotonin 4 receptor brain binding and personality trait Neuroticism - A positron emission tomography study in depressed patients and healthy individuals [0.03%]
五羟色胺4受体脑内结合与神经质人格特质无相关性-抑郁症患者和健康人的正电子发射断层扫描研究
Astrid Tougaard Mikkelsen,Kristian Høj Reveles Jensen,Martin Balslev Jørgensen et al.
Astrid Tougaard Mikkelsen et al.
Serotonergic neurotransmission has been linked to normal personality functioning, including the five-factor personality trait Neuroticism, which is a robust risk factor for Major Depressive Disorder (MDD). The serotonin 4 receptor (5-HT4R) ...
Co-expression of prepulse inhibition and Schizophrenia genes in the mouse and human brain [0.03%]
schizophrenia 基因在小鼠和人类脑中的协同表达
Lillian Garrett,Dietrich Trümbach,Donghyung Lee et al.
Lillian Garrett et al.
Schizophrenia is a complex psychiatric disorder with genetic and phenotypic heterogeneity. Accumulating rare and genome-wide association study (GWAS) common risk variant information has yet to yield robust mechanistic insight. Leveraging la...
Editorial: An interdisciplinary perspective on resilience - A special section in Neuroscience Applied [0.03%]
编者按：来自神经科学中的跨学科韧性观点-一个特殊专题
Stella D Voulgaropoulou,Thomaz F S Bastiaanssen,Nuno D Alves et al.
Stella D Voulgaropoulou et al.
Experiential avoidance and obsessive-compulsive symptoms in University students [0.03%]
大学生产生回避体验和强迫症症状的原因分析
Alexandre V Silva,Renan B de Christo,Raíza Alves-Pereira et al.
Alexandre V Silva et al.
Experiential avoidance is functional diagnostic dimension which refers to the unwillingness to engage with distressing thoughts, feelings, memories, and other internal experiences, despite the subsequent impairment it may cause. The spectru...
To eat or not to eat: A role for ghrelin and LEAP2 in eating disorders? [0.03%]
吃还是不吃？胃泌素和LEAP2在饮食紊乱中的作用？
Virginie Tolle,Chloe Tezenas du Montcel,Julia Mattioni et al.
Virginie Tolle et al.
Ghrelin is an orexigenic hormone that orchestrates many diverse behaviours of relevance for feeding control. It appears to operate as a hunger hormone, organizing food intake into meals and ensuring that we seek out and consume a variety of...
Yichun Li,Rajesh Nair,Syed Mohsen Naqvi
Yichun Li
Attention Deficit Hyperactivity Disorder (ADHD) is a highly prevalent human neurobehavioral and neurodevelopmental disorder worldwide. Recently, deep learning-based techniques have been exploited in ADHD detection and diagnosis due to their...