Prospects for improved prevention and treatment of neuropsychiatric disorders: Neuroscience Applied [0.03%]
神经科学在提高神经精神疾病防治方面的前景
Andreas Meyer-Lindenberg,Suzanne L Dickson,Mark J Millan et al.
Andreas Meyer-Lindenberg et al.
Progress in Neuroscience and related fields of research is deepening our understanding of the causes and pathophysiology of neuropsychiatric disorders and opening new avenues for their improved control. Together with more refined diagnostic...
Precision psychiatry: The ultimate goal of neuroscience applied to mental health [0.03%]
精准精神病学：神经科学应用于精神卫生的最终目标
Estela Salagre,Eduard Vieta
Estela Salagre
Mechanisms underlying anxiety in Rett Syndrome: Translational insights from preclinical findings [0.03%]
雷特综合征焦虑的发生机制：前临床研究的启示
Bethan Impey,Tracey A Newman,David S Baldwin
Bethan Impey
•The role of serotonin in mechanisms of anxiety in Rett syndrome appears complex.•Mecp2 mutation alters HPA axis function but this is understudied in Rett syndrome.•Rett syndrome may inform understanding of anxiety in those with early li...
Risk-taking in traffic is associated with unhealthy lifestyle: Contribution of aggressiveness and the serotonin transporter genotype [0.03%]
交通冒险行为与不健康生活方式有关：攻击性和血清素转运蛋白基因的贡献
Tõnis Tokko,Diva Eensoo,Kadi Luht-Kallas et al.
Tõnis Tokko et al.
Objectives: Risk taking behaviour, including in traffic, is related to impulsivity and aggressiveness, and so is unhealthy lifestyle. The serotonin transporter gene promoter polymorphism (5-HTTLPR) has been associated wit...
Roger Adan
Roger Adan
Comparative effectiveness of long-acting injectable antipsychotics in a large naturalistic cohort across two European centers: Findings from the long-acting injectable antipsychotics collaborative (LAICO) study [0.03%]
欧洲两大中心自然队列中长效抗精神病药物的疗效比较：来自长效注射用抗精神病药物协作组（LAICO）研究的结果
Juan Antonio García-Carmona,Joshua Barnett,María Pilar Campos-Navarro et al.
Juan Antonio García-Carmona et al.
We aimed to evaluate and compare the use of the paliperidone palmitate-1 and 3-month (PP1M, PP3M), aripiprazole 1-month (A1M) and risperidone-LAI (RLAI) LAIs, using the following clinical outcomes: (1) the number of hospital admissions, (2)...
Microdosing with psychedelics to self-medicate for ADHD symptoms in adults: A prospective naturalistic study [0.03%]
成人使用微量迷幻剂自我治疗注意力缺陷多动障碍症状的前瞻性自然主义研究
Eline C H M Haijen,Petra P M Hurks,Kim P C Kuypers
Eline C H M Haijen
ADHD in adulthood is often overlooked, which negatively affects the individual's well-being. First-line pharmacological interventions are effective in many ADHD patients, relieving symptoms rapidly. However, there seems to be a proportion o...
A single subanaesthetic dose of the rapid-acting antidepressant S-ketamine raises presynaptic SV2A density in limbic regions of the Wistar Kyoto rat model of depression [0.03%]
单剂量麻醉剂S-氯胺酮升高抑郁模型Wistar大鼠 limbic脑区突触前SV2A密度
Simone Larsen Bærentzen,Anna Lee Waszkiewicz,Majken Thomsen et al.
Simone Larsen Bærentzen et al.
The N-methyl-D-aspartate receptor (NMDA-R) antagonist S-ketamine has been approved as a rapid-acting antidepressant for treatment-resistant depression (TRD). The antidepressant mechanisms have not fully been elucidated; however, alterations...
Polygenic scores of subcortical brain volumes as possible modulators of treatment response in depression [0.03%]
抑郁症的亚皮层脑体积多基因评分作为可能的治疗反应调节因子
Vincenzo Oliva,Alfonso Martone,Giuseppe Fanelli et al.
Vincenzo Oliva et al.
A significant proportion of patients with major depressive disorder (MDD) do not experience remission after one or more pharmacological treatments. Research has explored brain structural measures, particularly hippocampal volume, as potenti...
Neurobiological traces of grief: Examining the impact of offspring loss after birth on rat mothers' brain and stress-coping behavior in the first week postpartum [0.03%]
丧子对母亲的影响：产后初生幼鼠丧子对母鼠大脑和应对压力的行为影响的神经生物学痕迹研究
Luisa Demarchi,Alice Sanson,Oliver J Bosch
Luisa Demarchi
The bond between a mother and her infant is one of the strongest social bonds found in mammals. Consequently, the loss of an infant has immense psychological and physiological effects on the caregiver. Despite the significance of this berea...