Using the grip strength effort task to measure reward processing dysfunction in schizophrenia and major depressive disorder [0.03%]
利用握力努力任务测量精神分裂症和抑郁症的奖赏处理功能障碍
Asad Malik,Shannon N Millard,Ailidh Finlayson et al.
Asad Malik et al.
The aims of the Reward Task Optimisation Consortium (RTOC) study (Bilderbeck et al., 2020) were to explore the validity, reliability, and feasibility of a battery of reward processing tasks for the development of new treatments for anhedoni...
Implementing psychedelic-assisted therapy: History and characteristics of the Swiss limited medical use program [0.03%]
瑞士限制性医疗使用项目实施迷幻辅助治疗的历史和特点分析
Matthias E Liechti,Peter Gasser,Helena D Aicher et al.
Matthias E Liechti et al.
This article describes the Swiss limited access program for psychedelic/3,4-methylenedioxymethamphetamine (MDMA)-assisted therapy. The Swiss Federal Office of Public Health can issue authorizations for the limited medical use of otherwise p...
Methodological challenges in psychedelic drug trials: Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - Rationale and study design [0.03%]
持续性抑郁(psilocybin治疗难治性抑郁症有效性和安全性的方法学挑战(EPIsoDE)——原理与研究设计）
Lea J Mertens,Michael Koslowski,Felix Betzler et al.
Lea J Mertens et al.
Psychedelics such as psilocybin have recently gained remarkable interest in both the specialist literature and the lay press because studies suggest that these substances may have great therapeutic potential in various psychiatric disorders...
María Arroyo-Araujo,Martien J H Kas
María Arroyo-Araujo
Metabolomics analysis of cerebrospinal fluid suggests citric acid cycle aberrations in bipolar disorder [0.03%]
基于脑脊液的代谢组分析提示二𫫇英酸循环在双相情感障碍中的异常变化
Erik Smedler,Alireza M Salehi,Aurimantas Pelanis et al.
Erik Smedler et al.
Mounting evidence indicates mitochondrial dysfunction in bipolar disorder pathophysiology. Here, we employed Proton Nuclear Magnetic Resonance Spectroscopy (1H NMR) of cerebrospinal fluid (CSF) samples from well-characterized bipolar disord...
Prospects for improved prevention and treatment of neuropsychiatric disorders: Neuroscience Applied [0.03%]
神经科学在提高神经精神疾病防治方面的前景
Andreas Meyer-Lindenberg,Suzanne L Dickson,Mark J Millan et al.
Andreas Meyer-Lindenberg et al.
Progress in Neuroscience and related fields of research is deepening our understanding of the causes and pathophysiology of neuropsychiatric disorders and opening new avenues for their improved control. Together with more refined diagnostic...
Precision psychiatry: The ultimate goal of neuroscience applied to mental health [0.03%]
精准精神病学：神经科学应用于精神卫生的最终目标
Estela Salagre,Eduard Vieta
Estela Salagre
Mechanisms underlying anxiety in Rett Syndrome: Translational insights from preclinical findings [0.03%]
雷特综合征焦虑的发生机制：前临床研究的启示
Bethan Impey,Tracey A Newman,David S Baldwin
Bethan Impey
•The role of serotonin in mechanisms of anxiety in Rett syndrome appears complex.•Mecp2 mutation alters HPA axis function but this is understudied in Rett syndrome.•Rett syndrome may inform understanding of anxiety in those with early li...
Risk-taking in traffic is associated with unhealthy lifestyle: Contribution of aggressiveness and the serotonin transporter genotype [0.03%]
交通冒险行为与不健康生活方式有关：攻击性和血清素转运蛋白基因的贡献
Tõnis Tokko,Diva Eensoo,Kadi Luht-Kallas et al.
Tõnis Tokko et al.
Objectives: Risk taking behaviour, including in traffic, is related to impulsivity and aggressiveness, and so is unhealthy lifestyle. The serotonin transporter gene promoter polymorphism (5-HTTLPR) has been associated wit...
Roger Adan
Roger Adan