Efficacy and safety of intravenously applied caffeine augmentation in electroconvulsive therapy [0.03%]
静脉注射咖啡因增效电休克治疗的有效性和安全性研究
Magdalena D Ridder,Sarah Ulrich,Richard Vettermann et al.
Magdalena D Ridder et al.
Electroconvulsive therapy (ECT) is a neuromodulation procedure that uses short electrical pulses causing a brief generalized seizure to treat depression, mania, schizophrenia, and catatonia. Achieving sufficient seizure length is crucial fo...
Polygenic scores and antidepressant treatment outcomes in major depression: a critical integrative review [0.03%]
抑郁症的多基因评分与抗抑郁治疗效果：批判性综合评价
Alessandro Serretti,Chiara Fabbri,Giuseppe Fanelli;European College of Neuropsychopharmacology (ECNP) Pharmacogenomics & Transcriptomics Network;Bernhard T Baune
Alessandro Serretti
Major depressive disorder (MDD) shows a large heterogeneity in antidepressant treatment outcome, a variability explained in part by common-variant liability captured by polygenic scores (PGSs). We performed a review of PubMed- and Google Sc...
Improving the diagnosis of bipolar disorder through machine learning - when is the time right? [0.03%]
机器学习改善双相情感障碍的诊断-何时才是良机？
Anna Luisa Klahn
Anna Luisa Klahn
Psychological resilience in trench warfare: Leveraging mental health frameworks for Ukrainian soldiers [0.03%]
堑壕战中的心理韧性：利用心理健康框架增强乌克兰士兵的韧性
Iryna Frankova,Vladyslav Klochkov,Marta Pyvovarenko et al.
Iryna Frankova et al.
The ongoing Russia-Ukraine War has highlighted the profound psychological toll of asymmetrical and hybrid warfare on military personnel, underscoring the need for tailored mental health interventions. This opinion paper examines the psychol...
The gut microbiota's role in bulimia nervosa and binge eating disorder: etiological insights and therapeutic implications from a scoping review [0.03%]
肠道微生物组在神经性贪食症和暴食症中的作用：系统评价的病因学见解和治疗意义
Silvia Tempia Valenta,Anna Rita Atti,Federica Marcolini et al.
Silvia Tempia Valenta et al.
This scoping review synthesizes emerging evidence on the relationship between gut microbiota and eating disorders (EDs), particularly bulimia nervosa (BN) and binge eating disorder (BED). An electronic search was conducted in the PubMed/MED...
Using the grip strength effort task to measure reward processing dysfunction in schizophrenia and major depressive disorder [0.03%]
利用握力努力任务测量精神分裂症和抑郁症的奖赏处理功能障碍
Asad Malik,Shannon N Millard,Ailidh Finlayson et al.
Asad Malik et al.
The aims of the Reward Task Optimisation Consortium (RTOC) study (Bilderbeck et al., 2020) were to explore the validity, reliability, and feasibility of a battery of reward processing tasks for the development of new treatments for anhedoni...
Implementing psychedelic-assisted therapy: History and characteristics of the Swiss limited medical use program [0.03%]
瑞士限制性医疗使用项目实施迷幻辅助治疗的历史和特点分析
Matthias E Liechti,Peter Gasser,Helena D Aicher et al.
Matthias E Liechti et al.
This article describes the Swiss limited access program for psychedelic/3,4-methylenedioxymethamphetamine (MDMA)-assisted therapy. The Swiss Federal Office of Public Health can issue authorizations for the limited medical use of otherwise p...
Methodological challenges in psychedelic drug trials: Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - Rationale and study design [0.03%]
持续性抑郁(psilocybin治疗难治性抑郁症有效性和安全性的方法学挑战(EPIsoDE)——原理与研究设计）
Lea J Mertens,Michael Koslowski,Felix Betzler et al.
Lea J Mertens et al.
Psychedelics such as psilocybin have recently gained remarkable interest in both the specialist literature and the lay press because studies suggest that these substances may have great therapeutic potential in various psychiatric disorders...
María Arroyo-Araujo,Martien J H Kas
María Arroyo-Araujo
Metabolomics analysis of cerebrospinal fluid suggests citric acid cycle aberrations in bipolar disorder [0.03%]
基于脑脊液的代谢组分析提示二𫫇英酸循环在双相情感障碍中的异常变化
Erik Smedler,Alireza M Salehi,Aurimantas Pelanis et al.
Erik Smedler et al.
Mounting evidence indicates mitochondrial dysfunction in bipolar disorder pathophysiology. Here, we employed Proton Nuclear Magnetic Resonance Spectroscopy (1H NMR) of cerebrospinal fluid (CSF) samples from well-characterized bipolar disord...