Special characteristics of human astrocytes and their roles in brain homeostasis [0.03%]
人类星形胶质细胞的特殊特征及其在脑内稳态中的作用
Ilari Kousa,Karo Talvio,Ulla-Kaisa Peteri et al.
Ilari Kousa et al.
Human astrocytes differ morphologically, functionally, and in their gene expression patterns from murine astrocytes. The astrocytic heterogeneity and complexity observed in the mouse brain are multiplied in humans, evident in primate-specif...
Machine learning for immune biomarkers in severe mental illness: a systematic review [0.03%]
精神疾病免疫生物标志物的机器学习研究：系统综述
Rayan Slatni,Federica Colombo,Paolo Enrico et al.
Rayan Slatni et al.
The integration of machine learning (ML) approaches with immune biomarker research may facilitate the identification of candidate markers for achieving personalized medicine approaches in severe mental illnesses (SMI). This systematic revie...
Critical uncertainties in preclinical research: Navigating trust, technology, and ethics [0.03%]
前期研究中的关键不确定性：信任、技术与伦理的考量
Indrek Heinla,Vootele Voikar,Hilary Gates et al.
Indrek Heinla et al.
Animal use in preclinical research is facing growing scientific, ethical and political scrutiny in Europe. Researchers are increasingly required to justify in vivo studies and are urged to replace them with New Approach Methodologies (NAMs)...
Positive effects of brief body exercises on mood: An interventional EMA study [0.03%]
简短的身体锻炼对情绪的积极影响：一种干预式体验抽样研究
Lea Nitzpon,Johanna Rehder,Richard Hohmann et al.
Lea Nitzpon et al.
Short bouts of physical activity in daily life are associated with affective well-being and may promote mental health. However, the causality and differential effects of distinct physical activity types remain unknown. This study investigat...
Weight matters: Higher BMI is associated with changes in the brain connectome in health and depression [0.03%]
体重很重要：较高的BMI与健康和抑郁状态下的大脑连接组变化有关
Aicha Bouzouina,Marius Gruber,Tong Zhao et al.
Aicha Bouzouina et al.
Overweight and obesity are bidirectionally associated with major depressive disorder (MDD). However, the underlying mechanisms remain unknown. Here, we investigated whether the body mass index (BMI) is associated with alterations in the str...
Application of the research domain criteria in early-phase clinical development of transdiagnostic neurotherapeutics: A multidisciplinary perspective [0.03%]
跨诊断神经治疗早期临床开发中研究领域标准的应用：多学科视角
Igor Magaraggia,Franco Di Cesare,Jordi Alonso et al.
Igor Magaraggia et al.
Transdiagnostic, dimensional frameworks such as the Research Domain Criteria (RDoC) are increasingly regarded as promising vehicles for precision neuropsychiatric drug development, yet no treatment has been approved that was explicitly deve...
Supporting mental health in war: Knowledge transfer through ECNP traumatic stress network webinars [0.03%]
战时支持心理健康：通过ECNP创伤应激网络研讨会进行知识转移
Iryna Frankova,Eric Vermetten,Olena Zhabenko et al.
Iryna Frankova et al.
On February 24, 2022, Russia's invasion of Ukraine marked a significant escalation of the armed conflict that began in 2014. In response, Traumatic Stress Network of the European College of Neuropsychopharmacology (ECNP) launched the "Hot T...
Data welfare is animal welfare: Building a WellFAIR research ecosystem [0.03%]
数据福祉即动物福祉：构建WellFAIR研究生态系统
Benoit Petit-Demoulière,Damien Huzard
Benoit Petit-Demoulière
Statistical process control for real-time monitoring in clinical psychology: State of the art and future research agenda [0.03%]
临床心理学实时监测的统计过程控制：现状与未来研究方向
Evelien Schat,Marieke J Schreuder,Eva Ceulemans
Evelien Schat
Mental disorders place a substantial burden on individuals and society, underscoring the need for preventive interventions that can be delivered to the right person at the right time. This, in turn, requires real-time monitoring of person-s...
Integrating physical healthcare into psychiatry for severe mental illness: A narrative review and position statement from the ECNP PAN-Health group [0.03%]
严重精神疾病的心理治疗中融入物理保健：ECNP PAN-健康小组的叙事性评审与立场声明
René Ernst Nielsen,Heidi Taipale,Samuele Cortese et al.
René Ernst Nielsen et al.
Individuals with severe mental illness (SMI) face significantly reduced life expectancy, mainly driven by natural causes such as cardiovascular disease, pulmonary disease, cancer, and stroke. Although medical care has advanced, the mortalit...