A review of psychedelics trials completed in depression, informed by European regulatory perspectives [0.03%]
基于欧洲监管视角的抑郁症迷幻剂临床试验述评
Francisca Silva,Florence Butlen-Ducuing,Lorenzo Guizzaro et al.
Francisca Silva et al.
There is a growing body of clinical research on the therapeutic potential of psychedelics for the treatment of mental health disorders, notably depression. Accordingly, the new revision of the European Medicines Agency guideline on the clin...
Capturing the continuum in biopsychosocial research: Measurement challenges within transdiagnostic and dimensional approaches to mental disorders [0.03%]
生物心理社会研究中连续性的捕捉：跨诊断和维度方法在精神障碍测量中的挑战
Anna Schulze,Stefanie Lis
Anna Schulze
Schizophrenia management: Systematic review of current medications and Phase-3 agents (2008-2024) [0.03%]
schizophrenia管理：当前药物和三期药物的系统回顾（2008-2024）
Salma Abdelmoteleb,Jayant Totlani,Salma Ramadan et al.
Salma Abdelmoteleb et al.
This systematic review evaluates psychiatric medications for schizophrenia approved between 2008 and 2024, considering regulatory practices and approvals across multiple regions, including the United States, Europe, and Asian countries. It ...
Conducting CNS trials during a public health emergency - Lessons learned from the COVID-19 pandemic: A joint ISCTM/ECNP working group consensus paper [0.03%]
公共卫生紧急状态下的中枢神经系统临床试验开展——COVID-19大流行期间的教训：ISCTM和ECNP工作组共识文件
Kemi Olugemo,Dragana Bugarski-Kirola,Gerard R Dawson et al.
Kemi Olugemo et al.
A joint working group between the International Society of CNS Clinical Trials and Methodology (ISCTM) and the European College of Neuropsychopharmacology (ECNP) was formed in the latter part of 2020 to explore possible ways to mitigate the...
Longitudinal development of resting-state functional connectivity in adolescents with and without internalizing disorders [0.03%]
内部化障碍青少年的功能连接纵向发展研究
Eline F Roelofs,Janna Marie Bas-Hoogendam,Anderson M Winkler et al.
Eline F Roelofs et al.
Longitudinal studies using resting-state functional magnetic resonance imaging (rs-fMRI) focused on adolescent internalizing psychopathology are scarce and have mostly investigated standardized treatment effects on functional connectivity (...
Neuroinflammation in comorbid depression in Alzheimer's disease: A pilot study using post-mortem brain tissue [0.03%]
阿尔茨海默病伴发抑郁的神经炎症：一项死后脑组织的初步研究
Jordan T Lin,Mizuki Morisaki,Srisharnitha A Sampathkumar et al.
Jordan T Lin et al.
Comorbid depression and Alzheimer's disease (AD) is associated with poorer prognosis than either condition alone. Neuroinflammation has been implicated in the pathogenesis and progression of both depression and AD, but much of the existing ...