Progress in the efficacy and mechanism of spinal cord stimulation in neuropathological pain [0.03%]
神经病理性疼痛的脊髓刺激疗法的有效性和机制研究进展
Shun-Lian Li,Jing Li,Hui-Chan Xu et al.
Shun-Lian Li et al.
Neuropathic pain (NP) is a long-term recurrent disease caused by somatosensory nervous system injury, with spontaneous pain, hyperalgesia, ectopic pain, and paresthesia as the main clinical manifestations. It adversely affects patients' qua...
Xiao-Xi Zhang,Nai-Xin Zhang,De-Xing Liu et al.
Xiao-Xi Zhang et al.
Esketamine is dextrorotatory ketamine, which is an enantiomer of ketamine. Compared with ketamine, it has the advantages of a fast metabolism, fewer side effects, and strong pharmacological effects, so it is more suitable for clinical use. ...
Qiu-Lin Wang,Chang-Le Fang,Xue-Yan Huang et al.
Qiu-Lin Wang et al.
Alzheimer's disease (AD) is a degenerative brain disease with complex clinical manifestations and pathogeneses such as abnormal deposition of beta-amyloid protein and inflammation caused by the excessive activation of microglia. CXC motif c...
The role of microglia in Alzheimer's disease and progress of treatment [0.03%]
小胶质细胞在阿尔茨海默病中的作用及治疗进展
Yi-Huan Guan,Ling-Jing Zhang,Shi-Ya Wang et al.
Yi-Huan Guan et al.
Microglia are permanent immune cells of the central nervous system. Microglia play an important role in the pathological process of Alzheimer's disease (AD). They are mainly involved in the uptake and clearance of amyloid-β (Aβ), as well ...
Research progress of anti-γ-aminobutyric acid B receptor encephalitis and a case report of paraneoplastic associated encephalitis and treatment analysis [0.03%]
抗γ-氨基丁酸B受体脑炎研究进展及伴发肿瘤性脑炎1例报告与治疗分析
Yi-Kun Lv,Hai-Qing Zhang,Jun Zhang
Yi-Kun Lv
Encephalitis is one of the common diseases in neurology. Early diagnosis and appropriate treatments are essential. Autoimmune encephalitis (AE) generally refers to a type of encephalitis mediated by autoimmune mechanisms. It is gradually co...
The role of intracerebral dopamine D1 and D2 receptors in sleep-wake cycles and general anesthesia [0.03%]
脑内多巴胺D1和D2受体在觉醒-睡眠周期及全麻中的作用研究
Jie Zhang,Jia Li,Cheng-Xi Liu et al.
Jie Zhang et al.
Dopamine (DA), a monoamine neurotransmitter, is synthesized and released mainly by neurons in the ventral tegmental area and the substantia nigra (SN) pars compacta of the midbrain. DA and its receptors are essential for the regulation of a...
An integrated analysis of hypoxic-ischemic encephalopathy-related cell sequencing outcomes via genes network construction [0.03%]
基于基因网络构建的缺氧缺血性脑病相关细胞测序结果的综合分析
Hong-Su Zhou,Ting-Bao Chen
Hong-Su Zhou
Hypoxic-ischemic encephalopathy (HIE) is one of the main causes of morbidity and severe neurological deficits in neonates. This study aimed to find core genes and their potential roles in HIE with the help of single-cell sequencing (SCS) te...
Lu Tong Ke Li protects neurons from injury by regulating inflammation in rats with brain trauma [0.03%]
芦通颗粒通过调控炎症反应保护脑外伤大鼠神经元损伤作用的研究
Jie Chen,Ting-Ting Li,Ting-Bao Chen et al.
Jie Chen et al.
Currently, there is no effective therapy for traumatic brain injury (TBI). Therefore, this study was conducted to determine the protective effect of Lu Tong Ke Li (LTKL), a Chinese medicine, for TBI in experimental animals. The TBI rat mode...
Intracranial hemorrhage following drainage of chronic subdural effusion and hematoma: A case report and review of the literature [0.03%]
慢性硬膜下液体和血肿引流后颅内出血的病例报告及文献回顾
Peng Wen,Wen-Long Xu,Huan Chen
Peng Wen
Acute intracranial hemorrhage (AIH) after drainage of chronic subdural hematoma is a rare but serious complication. An 86-year-old man with bilateral frontotemporal subdural effusion, hematoma, and cerebral hernia was admitted to our depart...
Case Reports
Ibrain. 2022 Feb 16;8(1):68-77. DOI:10.1002/ibra.12022 2022
Differences between cultured cortical neurons by trypsin and papain digestion [0.03%]
胰蛋白酶和木瓜酶消化法培养皮层神经元的差异性研究
Chang-Yan Hu,Ruo-Lan Du,Qiu-Xia Xiao et al.
Chang-Yan Hu et al.
The objective of this study was to compare the efficiency of trypsin and papain in neuronal digestion and determine which enzyme is more efficient. Cortical tissues were obtained from Sprague-Dawley (SD) rats. According to the different dig...