Suppression of SAMSN1 contributes to neuroprotection in neonatal rats suffering from hypoxic-ischemic encephalopathy injury [0.03%]
SAMSN1抑制作用有助于缺氧缺血性脑病新生大鼠的神经保护作用
Yi-Bo Wang,Zong-Jin Gan,Jun-Yan Zhang et al.
Yi-Bo Wang et al.
This article aims to detect the effect of SAM domain, SH3 domain, and nuclear localization signal 1 (SAMSN1) in neonatal rats with neurological dysfunction induced by hypoxia and ischemia (HI). The HI model was created using 7-day postnatal...
A typically progressive dissection of the internal carotid artery with recurrent hiccups: A case report with continuous 2-year data recording [0.03%]
以内科性颈内动脉夹层合并复发性呃逆为主要表现的烟雾病一例报告及两年随访
Zong-Min Zhang,Xin-Xin Yang,Li Ling et al.
Zong-Min Zhang et al.
Patients with internal carotid artery dissection (ICAD) usually report headache, neck pain, Horner's syndrome, and ischemic stroke. Because the posterior cranial nerve is involved, some patients may show different forms of posterior cranial...
Case Reports
Ibrain. 2022 Nov 9;9(1):124-129. DOI:10.1002/ibra.12074 2022
Effect of sulfonamide derivatives of phenylglycine on scopolamine-induced amnesia in rats [0.03%]
苯基甘氨酸磺胺衍生物对骚派胺致大鼠遗忘的影响
Ankit Ganeshpurkar,Ravi Singh,Pratigya Tripathi et al.
Ankit Ganeshpurkar et al.
Alzheimer's disease is a neurodegenerative disease responsible for dementia and other neuropsychiatric symptoms. In the present study, compounds 30 and 33, developed earlier in our laboratory as selective butyrylcholinesterase inhibitors, w...
Yi-Ting Peng,Cheng-Dong Yuan,Yi Zhang
Yi-Ting Peng
The basal forebrain is a group of nerve nuclei on the ventral side of the ventral ganglion, composed of γ-aminobutyric acid neurons, glutamatergic neurons, cholinergic neurons, and orexigenic neurons. Previous studies have focused on the i...
Nanoparticle delivery through the BBB in central nervous system tuberculosis [0.03%]
纳米颗粒通过BBB在中枢神经系统结核病中的传输作用
Anna Griego,Edoardo Scarpa,Valeria De Matteis et al.
Anna Griego et al.
Recent advances in Nanotechnology have revolutionized the production of materials for biomedical applications. Nowadays, there is a plethora of nanomaterials with potential for use towards improvement of human health. On the other hand, ver...
Nigella sativa and its nano-mediated approach toward management of neurodegenerative disorders: A review [0.03%]
nigella sativa及其纳米介导方法在神经退行性疾病管理中的作用：综述
Chaitali G Gawas,Sakshi Mathur,Minal Wani et al.
Chaitali G Gawas et al.
Nigella sativa L., also known as black seed or black cumin, is a plant that has been used for centuries. In the past, this flowering plant was used as a food preservative and medicinal herb. A vital component of Nigella sativa, thymoquinone...
Animal models of chemotherapy-induced peripheral neuropathy for hematological malignancies: A review [0.03%]
化疗诱导的血液系统恶性肿瘤周围神经病变动物模型的研究进展
Xiaoli Lv,Yingwei Mao,Song Cao et al.
Xiaoli Lv et al.
Chemotherapy is one of the main treatments for hematologic malignancies. However, chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common long-term toxic reactions in chemotherapy, and the occurrence of CIPN affects pati...
Ketamine as a therapeutic agent in major depressive disorder and posttraumatic stress disorder: Potential medicinal and deleterious effects [0.03%]
氯胺酮作为治疗重度抑郁症和创伤后应激障碍的药物：潜在的疗效与危害
Bhuvi Sachdeva,Punya Sachdeva,Shampa Ghosh et al.
Bhuvi Sachdeva et al.
Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are the most common causes of emotional distress that impair an individual's quality of life. MDD is a chronic mental illness that affects 300 million people across th...
The emerging mechanism behind viral infections and extracellular vesicles hypotheses leading to neuroinflammation and Alzheimer's disease pathology [0.03%]
病毒感染和细胞外囊泡诱导神经炎症及阿尔茨海默病假说及其机制研究进展
Mai M Anwar
Mai M Anwar
Despite decades of repeated and intense research, the etiology of sudden Alzheimer's disease (AD) symptoms is still unclear. AD progressive pathology mainly involves neuron damage, depositions of amyloid-beta (Aβ), and hyperphosphorylated ...
Effects of different injection methods of propofol anesthesia on the behavior and electroencephalography recording in mice [0.03%]
不同给药方式的异丙酚麻醉对小鼠行为及脑电图记录的影响
Dan Luo,Shi-Yu Chen,Yu Zhang
Dan Luo
Propofol is commonly used in mice studies on the mechanism of general anesthesia. The administration routes of propofol include intraperitoneal injection, single tail vein injection, and continuous tail vein pumping. The aim of this study i...