The alternative 3' splice site of GPNMB may promote neuronal survival after neonatal hypoxic-ischemic encephalopathy injury [0.03%]
缺氧缺血性脑病损伤后GPNMB的可选3'拼接位点可能促进神经元存活
Guo-Jiao Chen,Shan-Shan Yan,Jing-Han Zhang et al.
Guo-Jiao Chen et al.
This study aimed to decipher the effect of glycoprotein nonmetastatic melanoma protein B (GPNMB) on neonatal hypoxic-ischemic encephalopathy (NHIE) and its potential molecular mechanism. The hypoxic-ischemic (HI) model was established in 7-...
Downregulating EVA1C exerts the potential to promote neuron growth after neonatal hypoxic-ischemic encephalopathy injury associated with alternative splicing [0.03%]
下调EVA1C在促进新生儿缺氧缺血性脑病神经元损伤后再生中的作用及可变剪接机制研究
Yue Hu,Rong Rong,Yi Wang et al.
Yue Hu et al.
Neonatal hypoxic-ischemic encephalopathy (NHIE) is one of the major diseases in newborns during the perinatal stage, which globally is the main reason for children's morbidity and mortality. However, the mechanism of NHIE still remains poor...
Research progress on the effects and mechanisms of anesthetics on neural stem cells [0.03%]
麻醉药对神经干细胞作用及机制研究进展
Ji Zhang,Quan-Yuan Chang,Loris Rizzello et al.
Ji Zhang et al.
Exposure to anesthetic drugs has been proven to seriously affect developing animals in terms of neural stem cells' (NSCs') proliferation, differentiation, and apoptosis. This can severely hamper the development of physiological learning and...
Thoracic epidural arteriovenous malformation causing rapidly progressive myelopathy and mimicking an acute transverse myelitis: A case report [0.03%]
迅速进展性脊髓病和类似急性横贯性脊髓炎的胸廓硬膜外动静脉畸形一例报告
Hao Yuan,Yu Pi,Hong-Su Zhou et al.
Hao Yuan et al.
Clinical symptoms of spinal arteriovenous malformations (AVMs) combined with acute spontaneous hemorrhage lack specificity, which leads to misdiagnosis and delays treatment. The current study aimed to analyze the causes of misdiagnosis and ...
Case Reports
Ibrain. 2022 Oct 26;8(4):492-499. DOI:10.1002/ibra.12070 2022
Neuroscience of consciousness in the locked-in syndrome: Prognostic and diagnostic review [0.03%]
闭锁综合征意识的神经科学：预后和诊断评估
Berenika Maciejewicz
Berenika Maciejewicz
The neurological illness known as a locked-in syndrome is brought on by damage to the brainstem, usually as a consequence of a stroke. It is characterized by total paralysis with intact consciousness and cognitive capacity. The subjective e...
Efficacy of the lumbar sympathetic ganglion block in lower limb pain and its application prospects during the perioperative period [0.03%]
腰交感神经阻滞治疗下肢疼痛的有效性及其围手术期应用前景
Jing-Han Zhang,Yan-Ping Deng,Min-Jian Geng
Jing-Han Zhang
The sympathetic nervous system is involved in the physiological pathogenesis of many different types of chronic pain. Sympathetic blocks can interrupt the reflex control system by intercepting the noxious afferent fibers accompanying autono...
Protective effect of isoflurane preconditioning on neurological function in rats with HIE [0.03%]
异氟醚预处理对新生儿寒酸相关脑损伤的神经保护作用研究
Yi Fei-Sun,Miao Huang,Hao-Yue Qin et al.
Yi Fei-Sun et al.
Hypoxic-ischemic encephalopathy (HIE) is an important cause of neonatal death and disability, which can lead to long-term neurological and motor dysfunction. Currently, inhalation anesthetics are widely used in surgery, and some studies hav...
Advances in the study of the relationship between Alzheimer's disease and the gastrointestinal microbiome [0.03%]
阿尔茨海默病与肠道微生态关系的研究进展
Xin-Yan Li,Hao-Yue Qin,Ting-Ting Li
Xin-Yan Li
There are many trillions of bacteria in the gastrointestinal microbiome (GM). Their ecological dysregulation can contribute to the development of certain neurodegenerative diseases, including Alzheimer's disease (AD). AD is common dementia ...
Considering gene therapy to protect from X-linked deafness DFNX2 and associated neurodevelopmental disorders [0.03%]
针对伴X染色体隐性遗传 deafness-dementia-lymphedema 综合征的基因治疗策略研究
Jean Defourny
Jean Defourny
Mutations and deletions in the gene or upstream of the gene encoding the POU3F4 transcription factor cause X-linked progressive deafness DFNX2 and additional neurodevelopmental disorders in humans. Hearing loss can be purely sensorineural o...
Breakthroughs on the clinical management of headache and questions that need to be solved [0.03%]
头痛的临床处理的新进展及尚待解决的问题
Yu-Cong Liu,Ting-Ting Yang,Jing Li et al.
Yu-Cong Liu et al.
Headache is a common refractory disorder among adults, especially in females, which can lower the quality of life in patients and increase medical costs. Nearly 90% of people have been affected by headache disorders during their lifetime. T...