Aberrant TDP-43 phosphorylation: a key wind gap from TDP-43 to TDP-43 proteinopathy [0.03%]
异常的TDP-43磷酸化：从TDP-43到TDP-43蛋白病的关键缺口
Zi-Qi Huang,Zhi-Sheng Ba,Nan-Qu Huang et al.
Zi-Qi Huang et al.
TDP-43 proteinopathy is a kind of neurodegenerative diseases related to the TAR DNA-binding protein of 43-kDa molecular weight (TDP-43). The typical neurodegenerative diseases include amyotrophic lateral sclerosis (ALS), frontotemporal loba...
ApoE transiently regulates hippocampus amyloid-beta deposition to stable learning and memory ability in adult rats exposed in sevoflurane [0.03%]
老年鼠短暂吸入七氟醚致学习记忆能力稳态失衡的APOE介导的调控机制研究
Shan Xu,Jun-Li Jiang,Chao Zhang et al.
Shan Xu et al.
Objective: Post-operative cognitive dysfunction (POCD) is a common central nervous system complication after surgery. Inhaled anesthetic sevoflurane is thought to have harmful effects on the developing and aged nerves, bu...
Xiu-Ying He,Ru-Rong Wang,Ting-Hua Wang
Xiu-Ying He
Parkinson's disease (PD) is a common neurodegenerative disease in the central nervous system. The pathological manifestations mainly consist of α-synuclein accumulation, degeneration and death of dopaminergic neurons, and insufficient dopa...
New progress of isoflurane, sevoflurane and propofol in hypoxic-ischemic brain injury and related molecular mechanisms based on p 75 neurotrophic factor receptor [0.03%]
基于p75神经营养因子受体在缺氧缺血性脑损伤中异氟醚、七氟烷和丙泊酚的新进展及分子机制相关研究
Yi Zhu,Hong-Su Zhou,Dong-Qin Chen et al.
Yi Zhu et al.
Hypoxic ischemic brain injury (HIBI) is one of the most common clinical disorders, especially in neonates. The complex pathophysiology of HIBI is an important cause of disability and even death of patients, however, being without effective ...
Research progress of the paraventricular thalamus in the regulation of sleep-wake and emotional behaviors [0.03%]
腹侧丘脑核在调控觉醒和情绪行为中的研究进展
Xiao-Li Bu,Cheng-Xi Liu,Bao Fu
Xiao-Li Bu
The paraventricular thalamus (PVT) is a major component of the midline structure of the thalamus. It is one of the nonspecific nuclei of the thalamus, which plays a great role in the regulation of cortical arousal. PVT, an important node in...
Zhong Luo,Jian Wang,Piao Cao et al.
Zhong Luo et al.
The aim of this article was to analyze the clinical and genetic characteristics of a patient with Huntington's disease and her family. We analyzed the clinical data of a patient with Huntington's disease and her family members in the Depart...
Case Reports
Ibrain. 2022 Jun 17;8(2):241-245. DOI:10.1002/ibra.12049 2022
Effects of subanesthesia dose S-ketamine induction on postoperative psychiatric complications after gynecological surgery [0.03%]
妇科手术中使用亚麻醉剂量的S-氯胺酮诱导对术后精神并发症的影响
Fan Zhang,Jun Ding,Man Luo et al.
Fan Zhang et al.
Ketamine may become an important drug for multimodal analgesia regime again because of its strong analgesic effects and retaining the advantage of spontaneous breathing. The present study was designed to explore the influences of different ...
The differentially expressed proteins related to clinical viral encephalitis revealed by proteomics [0.03%]
基于蛋白质组学的临床病毒性脑炎相关差异表达蛋白研究
Qian Wang,Shan-Shan Yan,Jun-Yan Zhang et al.
Qian Wang et al.
To screen out the prospective biomarkers of viral encephalitis (VE), analyze the biological process and signaling pathways involved by differentially expressed proteins (DEPs). A total of 11 cerebrospinal fluid (CSF) samples with VE and 5 w...
Qingyang Luo,Song Wen,Xinran Tan et al.
Qingyang Luo et al.
Stellate ganglion (SG) intervention is currently widely being studied in many kinds of chronic pain. As one of the convenient ways to treat the sympathetic nervous system, the indications for stellate ganglion intervention (SGI) include com...
Yu Pi,Chang-Le Fang,Zhang-Yu Su
Yu Pi
Glioma is one of the most common primary brain tumors, and mortality due to this disease is second only to cardiovascular and cerebrovascular diseases. In traditional surgery, it is difficult to eradicate glioma; often recurrence increases ...