Evidence against Neurodevelopmental Risks for Children Whose Fathers Use Valproate [0.03%]
父亲使用丙戊酸对儿童神经发育风险的证据不足
Kimford J Meador
Kimford J Meador
Jonathan D Browne,Peter W Kaplan
Jonathan D Browne
AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry...
Case Reports
NEJM evidence. 2026 Mar;5(3):EVIDmr2500286. DOI:10.1056/EVIDmr2500286 2026
Disclosure of Pregnancy-Related Privacy Risks in Clinical Research Post-Dobbs [0.03%]
多布斯裁决后临床研究中与怀孕相关的隐私风险披露
Ava Glazier,Willyanne DeCormier Plosky,Barbara E Bierer
Ava Glazier
AbstractInterventional clinical research often involves risks to participants of reproductive potential, requiring pregnancy testing, contraception, and reporting of incidental pregnancies. Since the Dobbs v. Jackson Women's Health Organiza...
Feasibility of PROSPECTOR - A Randomized Trial Evaluating Oral Challenge Duration in Penicillin Allergy Evaluation [0.03%]
关于青霉素过敏评估中口服激发持续时间的可行性研究（PROSPECTOR）——一项随机临床试验
Santiago Alvarez-Arango,Kimberly G Blumenthal
Santiago Alvarez-Arango
A Randomized Trial of Targeted Hyponatremia Correction in Hospitalized Patients [0.03%]
住院患者针对性低钠血症矫正的随机试验
Julie Refardt,Laura Potasso,Anissa Pelouto et al.
Julie Refardt et al.
Background: Chronic hyponatremia is associated with adverse outcomes, including falls, neurocognitive disorders, and mortality, but whether hyponatremia itself increases morbidity and mortality, or is simply an indicator ...
Randomized Controlled Trial
NEJM evidence. 2026 Mar;5(3):EVIDoa2500086. DOI:10.1056/EVIDoa2500086 2026
Trifluridine-Tipiracil with and without Bevacizumab in Colorectal Cancer [0.03%]
特氟瑞蒂皮拉西利联合或不联合贝伐单抗治疗结直肠癌
Maliha Nusrat,Ruizhi Zhao,Nadeem Khan et al.
Maliha Nusrat et al.
Background: In the phase 3 SUNLIGHT trial (Study of Trifluridine/Tipiracil With and Without Bevacizumab in Refractory Metastatic Colorectal Cancer Patients), trifluridine-tipiracil+bevacizumab (FTD-TPI+bev) improved the o...
Paenibacillus dendritiformis as a Cause of Destructive Meningitis in Infants [0.03%]
芽胞杆菌属树状分支细菌引起的婴儿破坏性脑膜炎病例报告
Danielle Smith,Rupa Garikipati,Kristen Bastug et al.
Danielle Smith et al.
AbstractInvasive infections due to Paenibacillus species pose a serious risk to young infants and have a high risk of neurologic sequelae. This report describes two infants with severe neurologic manifestations secondary to Paenibacillus de...
Infant Immunity after Maternal Nipocalimab in Severe Hemolytic Disease of the Fetus and Newborn [0.03%]
用于重度胎儿和新生儿溶血病的产妇尼波卡利单抗后的婴儿免疫力
Derek P de Winter,Kenneth J Moise,Leona E Ling et al.
Derek P de Winter et al.
Background: Antenatal treatment with nipocalimab, a neonatal Fc receptor (FcRn) blocker, delayed or prevented fetal anemia, as compared with a historical benchmark, in a phase 2 study of early-onset severe hemolytic disea...
Clinical Trial
NEJM evidence. 2026 Feb;5(2):EVIDoa2500097. DOI:10.1056/EVIDoa2500097 2026
Telemedicine Care on a Mobile Stroke Unit - Time and Tide Wait for No Man [0.03%]
流动中风单元的远程医疗服务——时不我待
Lee H Schwamm
Lee H Schwamm
John E Dobbs,Margaret D Krasne,Rakhi P Naik et al.
John E Dobbs et al.
AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry...
Case Reports
NEJM evidence. 2026 Feb;5(2):EVIDmr2500137. DOI:10.1056/EVIDmr2500137 2026