Aoun Zaib Khan,Farva Zaib Khan,Ahmed Sajid et al.
Aoun Zaib Khan et al.
AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry...
Case Reports
NEJM evidence. 2026 Apr;5(4):EVIDmr2400406. DOI:10.1056/EVIDmr2400406 2026
Wrist Splinting versus a Placebo Soft Bandage for Carpal Tunnel Syndrome [0.03%]
腕托与安慰性软绷带治疗腕管综合征的疗效比较研究
Isam Atroshi,Jesper Nordenskjöld,Kamelia Möllestam
Isam Atroshi
Background: Wrist splinting is a common treatment for carpal tunnel syndrome (CTS), but there is little evidence supporting its efficacy. Methods: ...
Randomized Controlled Trial
NEJM evidence. 2026 Apr;5(4):EVIDoa2500261. DOI:10.1056/EVIDoa2500261 2026
Israel Agaku
Israel Agaku
AbstractAnalysis of 2023-2024 National Health Interview Survey data suggest that prevalence of cigarette smoking among U.S. adults declined from 10.8% of the population in 2023 to 9.9% in 2024. Use of other tobacco products, including cigar...
Jiaojiao Liu,Shuk Hang Li,Naiqing Ye et al.
Jiaojiao Liu et al.
AbstractA new H3N2 variant (named subclade K) possesses several key hemagglutinin substitutions and is circulating widely during the 2025-2026 influenza season. We sought to determine whether the 2025-2026 seasonal influenza vaccine elicits...
Multistate Infant Botulism Outbreak Associated with Powdered Infant Formula [0.03%]
与婴儿配方奶粉相关的多州婴儿肉毒杆菌病暴发事件
Connie H Chung,Jason R Barash,Jacquelin L Castonguay et al.
Connie H Chung et al.
AbstractThis report details the identification of an outbreak of infant botulism linked to powdered infant formula in the United States. In October 2025, the Infant Botulism Treatment and Prevention Program, California Department of Public ...
Valproate Use by Fathers and Risk of Neurodevelopmental Disorders in Children [0.03%]
父亲使用丙戊酸盐与儿童神经发育障碍的风险关联性研究
Lin-Chieh Meng,Marleen M H J van Gelder,Hui-Min Chuang et al.
Lin-Chieh Meng et al.
Background: There is concern about the increased risk of neurodevelopmental disorders (NDDs) among offspring of fathers taking valproate within 90 days before conception. ...
Feasibility Trial of Prolonged versus Single-Dose Challenge in Penicillin Allergy [0.03%]
长效与单剂量给药治疗青霉素过敏的可行性试验
Morgan Rose,Sara Vogrin,Elise A Mitri et al.
Morgan Rose et al.
Background: We aimed to evaluate the feasibility of conducting a multicenter, double-blind, placebo-controlled trial of prolonged (i.e., multidose) compared with single-dose amoxicillin challenge in patients with a histor...
Randomized Controlled Trial
NEJM evidence. 2026 Mar;5(3):EVIDoa2500038. DOI:10.1056/EVIDoa2500038 2026
Targeted Treatment of Moderate Hyponatremia in Hospitalized Patients - Helpful or Unnecessary? [0.03%]
中度低钠血症的靶向治疗——有益还是多余？
Alexander Kumachev,Thomas E MacMillan
Alexander Kumachev
Alena Annbalou Hasenburg,Axel Grothey
Alena Annbalou Hasenburg
Evaluating Noninferiority in Clinical Trials with a Hierarchical End Point [0.03%]
临床试验中含层次结构终点的非劣效评价方法研究
John Gregson,Bjorn Redfors,David J Cohen et al.
John Gregson et al.
AbstractThe win ratio is a method for analyzing a clinical hierarchy of outcomes. It is most commonly applied to randomized clinical trials to evaluate the superiority of an intervention versus the standard of care. Once an intervention is ...