Aaron S Kelly,Megan O Bensignor,Daniel S Hsia et al.
Aaron S Kelly et al.
Background: Antiobesity medication may be useful for the treatment of pediatric obesity, yet few safe and effective options exist. We evaluated phentermine/topiramate (PHEN/TPM) for weight management in adolescents with o...
Statins and Left Ventricular Ejection Fraction Following Doxorubicin Treatment [0.03%]
他莫昔芬联合雷洛昔芬治疗绝经后乳腺癌的疗效及对血脂、左室射血分数的影响比较研究
W Gregory Hundley,Ralph D&#x;Agostino Jr,Teresa Crotts et al.
W Gregory Hundley et al.
Background: Statins taken for cardiovascular indications by patients with breast cancer and lymphoma during doxorubicin treatment may attenuate left ventricular ejection fraction (LVEF) decline, but the effect of statins ...
AI Estimation of Gestational Age from Blind Ultrasound Sweeps in Low-Resource Settings [0.03%]
基于盲扫超声的低资源环境下的人工智能估测孕周模型
Teeranan Pokaprakarn,Juan C Prieto,Joan T Price et al.
Teeranan Pokaprakarn et al.
Background: Ultrasound is indispensable to gestational age estimation and thus to quality obstetrical care, yet high equipment cost and the need for trained sonographers limit its use in low-resource settings. ...
Ethical Challenges to Improving Access to Human Papillomavirus Vaccines in Low- and Middle-Income Countries [0.03%]
提高低收入和中等收入国家获取人乳头瘤病毒疫苗的途径所面临的伦理挑战
Ahizechukwu C Eke,Vanessa B Kerry
Ahizechukwu C Eke
Michelle N Clements,Ian R White,Andrew J Copas et al.
Michelle N Clements et al.
Spyridon P Basourakos,Roman Gulati,Randy A Vince Jr et al.
Spyridon P Basourakos et al.
Background: Prostate-specific antigen screening has profoundly affected the epidemiology of prostate cancer in the United States. Persistent racial disparities in outcomes for Black men warrant re-examination of the harms...
Ruanne V Barnabas,Elizabeth R Brown,Maricianah A Onono et al.
Ruanne V Barnabas et al.
BACKGROUND: Single-dose human papillomavirus (HPV) vaccination, if efficacious, would be tremendously advantageous, simplifying implementation and decreasing costs. METHODS: We performed a randomized, multicenter, double-blind, controlled t...
Randomized Controlled Trial
NEJM evidence. 2022 Jun;1(5):EVIDoa2100056. DOI:10.1056/EVIDoa2100056 2022
Neonatal azithromycin administration for prevention of infant mortality [0.03%]
新生儿盐酸阿奇霉素用药以预防婴儿死亡事件
Catherine E Oldenburg,Ali Sié,Mamadou Bountogo et al.
Catherine E Oldenburg et al.
BACKGROUND: Biannual mass azithromycin administration reduces all-cause childhood mortality in some sub-Saharan African settings, with the largest effects in children 1 to 5 months of age. Azithromycin has not been distributed to children y...
Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management [0.03%]
痛风管理中阿罗普尿和非布索司特的疗效比较分析
James R O&#x;Dell,Mary T Brophy,Michael H Pillinger et al.
James R O&#x;Dell et al.
Background: The relative efficacy and safety of allopurinol and febuxostat when used according to current guidelines for the treatment of hyperuricemia are unknown. This double-blind noninferiority trial examined these is...