Michael Fralick,Kieran R Campbell
Michael Fralick
The Basics of Machine LearningWhen a person is pregnant, a key question is how to establish the "date" of the pregnancy. Classically, the date was based on the last menstrual period (LMP). For the past 3 decades or more, in high-resource co...
María-Fernanda Lorenzo-Gómez,Stephen Foley,J Curtis Nickel et al.
María-Fernanda Lorenzo-Gómez et al.
BACKGROUND: Recurrent urinary tract infections (UTIs), which consist of three or more episodes in 1 year or two or more infections in 6 months, affect 5% to 10% of women. MV140, a sublingual preparation of whole-cell inactivated bacteria, h...
The Peak Is Always in View - Observations from a Patient in a Clinical Trial in Lung Cancer [0.03%]
峰回路转——一位临床试验入组肺癌患者的感悟
Robert Barkman
Robert Barkman
The Peak Is Always in View In this Patient Platform, Professor Robert Barkman relays his experiences as a patient in a trial of immunotherapy for lung cancer.
Moses Taylor
Moses Taylor
My Experience as a SPRINT Clinical Trial Participant This Patient Platform is from Moses Taylor, a participant in the Systolic Blood Pressure Intervention Trial (SPRINT) that was published in the New England Journal of Medicine in November ...
Rebecca A Betensky
Rebecca A Betensky
Don't Be Blinded by the BlindingBlinding of participants and investigators is universally accepted as a critical component of a high-quality randomized clinical trial. In conjunction with random assignment, blinding protects against several...
Natalia E Castillo Almeida,Andre C Kalil
Natalia E Castillo Almeida
Molnupiravir: Is It Time to Move In or Move Out?With more than 250 million diagnosed cases and 5 million deaths, Covid-19 is our epoch-defining pandemic - and it is still ongoing. Despite the development of several effective Covid-19 vaccin...
Alex K Pearce,W Cameron McGuire,Atul Malhotra
Alex K Pearce
Prone Positioning in ARDSCovid-19 has greatly expanded the use of prone positioning for patients with respiratory failure. Pearce and colleagues review the physiology of prone positioning and the evidence for its use, including in nonintuba...
Can I Safely Discharge a Patient with a Substance Use Disorder Home with a Peripherally Inserted Central Catheter? [0.03%]
患有物质使用障碍的患者是否可以安全地带着外周插入的中心导管回家？
Ayesha Appa,Joshua A Barocas
Ayesha Appa
Discharging Patients Who Use Drugs Home with PICCAmid the U.S. overdose crisis, serious injection-related infections are rising. Determining where a patient goes after hospitalization can be a challenge due to the need for prolonged parente...
Amy J Romer,Sandy Johng,Jill Hsia et al.
Amy J Romer et al.
Cyanosis in a Newborn Immediately after BirthA male neonate, weighing 3.9 kg, was delivered via Cesarean section at 39 weeks of gestation. He cried immediately after birth, but his whole body appeared blue and he had low muscle tone that di...